目的分析入住神经内科重症监护室(NICU)的脑卒中患者高血糖控制状况并探讨血糖水平与死亡风险的关系。方法纳入2017年7月~2018年12月入住NICU时发生高血糖的脑卒中患者进行回顾性分析,将其分为死亡组和存活组,比较两组之间血糖控制状况...目的分析入住神经内科重症监护室(NICU)的脑卒中患者高血糖控制状况并探讨血糖水平与死亡风险的关系。方法纳入2017年7月~2018年12月入住NICU时发生高血糖的脑卒中患者进行回顾性分析,将其分为死亡组和存活组,比较两组之间血糖控制状况的差异,及其与死亡风险的关系。结果共纳入395例高血糖患者,其中死亡组22例,存活组373例。与存活组相比,死亡组的平均年龄(岁)(78.86±11.13 vs 67.81±16.04,P<0.01)、APACHEⅡ评分(分)(12.9±3.92 vs 10.78±3.01,P<0.05)、平均血糖值(mmol/L)(12.93±5.49 vs 10.7±4.56,P<0.01)、高血糖发生率(血糖>7.8 mmol/L)(83.31%vs 68.55%,P<0.01)、严重高血糖发生率(血糖>13.9 mmol/L)(36.01%vs 21.65%,P<0.01)、临床显著低血糖发生率(血糖<3.0 mmol/L)(0.28%vs 0.18%,P<0.05)、血糖漂移度(mmol/L)(4.20±1.44 vs 2.84±1.44,P<0.01)、最大血糖波动幅度(mmol/L)(17.34±8.48 vs 11.22±6.45,P<0.01)均明显增加,而目标血糖达标率(62.47%vs 78.07%,P<0.01)明显降低。多因素分析显示年龄(OR=1.083)、APACHEⅡ评分(OR=1.282)、平均血糖值(OR=1.424)是脑卒中合并高血糖患者死亡的独立危险因素。结论NICU住院脑卒中患者高血糖发生率高,血糖波动幅度大,尤其在死亡患者中更为明显,应重视血糖管理;其年龄、APACHEⅡ评分、平均血糖水平可能是死亡率增加的独立危险因素。展开更多
Samples of LiNi0.95-xCoxAl0.05O2 （x = 0.10 and 0.15） and LiNiO2, synthesized by the solid-state reaction at 725℃ for 24 h from LiOH-H2O, Ni2O3, Co2O3, and AI（OH）3 under an oxygen stream, were characterized by TG-...Samples of LiNi0.95-xCoxAl0.05O2 （x = 0.10 and 0.15） and LiNiO2, synthesized by the solid-state reaction at 725℃ for 24 h from LiOH-H2O, Ni2O3, Co2O3, and AI（OH）3 under an oxygen stream, were characterized by TG-DTA, XRD, SEM, and electrochemical tests. Simultaneous doping of cobalt and aluminum at the Ni-site in LiNiO2 was tried to improve the cathode performance for lithium-ion batteries. The results showed that co-doping （especially, 5 at.% A1 and 10 at.% Co） definitely had a large beneficial effect in increasing the capacity （186.2 mA.h/g of the first discharge capacity for LiNio.s.42OoaoAlo.0502） and cycling behavior （180.1 mA-h/g after 10 cycles for LiNio.85CooaoAlo.osO2） compared with 180.7 mA.h/g of the first discharge capacity and 157.7 mA.h/g of the tenth discharge capacity for LiNiO2, respectively. Differen- tial capacity versus voltage curves showed that the co-doped LiNio.95_xCoxmlo.osO2 had less intensity of the phase transitions than the pristine LiNiO2.展开更多
Samples of LiNi0.95-xCoxAl0.05O2（x=0.10 and 0.15） and LiNiO2,synthesized by the solid-state reaction at 725?℃ for 24?h from LiOH·H2O,Ni2O3,Co2O3,and Al（OH）3 under an oxygen stream,were characterized by TG-DT...Samples of LiNi0.95-xCoxAl0.05O2（x=0.10 and 0.15） and LiNiO2,synthesized by the solid-state reaction at 725?℃ for 24?h from LiOH·H2O,Ni2O3,Co2O3,and Al（OH）3 under an oxygen stream,were characterized by TG-DTA,XRD,SEM,and electrochemical tests. Simultaneous doping of cobalt and aluminum at the Ni-site in LiNiO2 was tried to improve the cathode performance for lithium-ion batteries. The results showed that co-doping （especially,5% Al and 10% Co in atomic fraction） definitely had a large beneficial effect in increasing the capacity （186.2?mA·h/g of the first discharge capacity for LiNi 0.85 Co 0.1 0Al 0.05 O2） and cycling behavior (180.1?mA·h/g after 10 cycles for LiNi0.95-xCoxAl0.05O2) compared with 180.7?mA·h/g of the first discharge capacity and 157.7?mA·h/g of the tenth discharge capacity for LiNiO2,respectively. Differential capacity versus voltage curves showed that the co-doped LiNi0.95-xCoxAl0.05O2 had less intensity of the phase transitions than the pristine LiNiO2.展开更多
The rapid development of portable and wearable electronic devices is responding to the urgent demand for high-efficiency flexible energy storage devices.Flexible supercapacitors,showing long cycle life,high power dens...The rapid development of portable and wearable electronic devices is responding to the urgent demand for high-efficiency flexible energy storage devices.Flexible supercapacitors,showing long cycle life,high power density,and good safety,are considered ideal candidates.Nevertheless,the relatively low energy density restricts their practical applications.With a large dielectric constant of 18-46,Ta_(2)O_(5)-based materials typically exhibit excellent electron-binding ability,which is critical for enhancing the energy density of supercapacitors.In this work,the free-standingβ-Ta_(2)O_(5)/single-walled carbon nanotubes(SWCNTs)composite film was prepared,with a highβ-Ta_(2)O_(5)loading of over 70%.By anchoringβ-Ta_(2)O_(5)nanoparticles onto the surface of SWCNTs,the system’s flexibility and conductivity were significantly enhanced,which also facilitated the intercalation electrodynamics of metal cations.As a result,the flexibleβ-Ta_(2)O_(5)/SWCNTs film exhibits excellent Li-ion storage performance,with a high volumetric specific capacitance of 392.3 F cm^(-3)at the scan rate of 10 mV s^(-1)and 198.9 F cm^(-3)at 500 mV s^(-1).In addition,the asymmetric device,assembled by theβ-Ta_(2)O_(5)/SWCNTs and activated carbon films,shows a high energy density of 45.5 Wh kg^(-1)at the power density of 10.8 kW kg^(-1).This technique opens up a new avenue for improving the energy density and rate performance of flexible supercapacitors.展开更多
文摘目的分析入住神经内科重症监护室(NICU)的脑卒中患者高血糖控制状况并探讨血糖水平与死亡风险的关系。方法纳入2017年7月~2018年12月入住NICU时发生高血糖的脑卒中患者进行回顾性分析,将其分为死亡组和存活组,比较两组之间血糖控制状况的差异,及其与死亡风险的关系。结果共纳入395例高血糖患者,其中死亡组22例,存活组373例。与存活组相比,死亡组的平均年龄(岁)(78.86±11.13 vs 67.81±16.04,P<0.01)、APACHEⅡ评分(分)(12.9±3.92 vs 10.78±3.01,P<0.05)、平均血糖值(mmol/L)(12.93±5.49 vs 10.7±4.56,P<0.01)、高血糖发生率(血糖>7.8 mmol/L)(83.31%vs 68.55%,P<0.01)、严重高血糖发生率(血糖>13.9 mmol/L)(36.01%vs 21.65%,P<0.01)、临床显著低血糖发生率(血糖<3.0 mmol/L)(0.28%vs 0.18%,P<0.05)、血糖漂移度(mmol/L)(4.20±1.44 vs 2.84±1.44,P<0.01)、最大血糖波动幅度(mmol/L)(17.34±8.48 vs 11.22±6.45,P<0.01)均明显增加,而目标血糖达标率(62.47%vs 78.07%,P<0.01)明显降低。多因素分析显示年龄(OR=1.083)、APACHEⅡ评分(OR=1.282)、平均血糖值(OR=1.424)是脑卒中合并高血糖患者死亡的独立危险因素。结论NICU住院脑卒中患者高血糖发生率高,血糖波动幅度大,尤其在死亡患者中更为明显,应重视血糖管理;其年龄、APACHEⅡ评分、平均血糖水平可能是死亡率增加的独立危险因素。
基金The project is financially supported by the National Natural Science Foundation of China (No. 20371038).
文摘Samples of LiNi0.95-xCoxAl0.05O2 （x = 0.10 and 0.15） and LiNiO2, synthesized by the solid-state reaction at 725℃ for 24 h from LiOH-H2O, Ni2O3, Co2O3, and AI（OH）3 under an oxygen stream, were characterized by TG-DTA, XRD, SEM, and electrochemical tests. Simultaneous doping of cobalt and aluminum at the Ni-site in LiNiO2 was tried to improve the cathode performance for lithium-ion batteries. The results showed that co-doping （especially, 5 at.% A1 and 10 at.% Co） definitely had a large beneficial effect in increasing the capacity （186.2 mA.h/g of the first discharge capacity for LiNio.s.42OoaoAlo.0502） and cycling behavior （180.1 mA-h/g after 10 cycles for LiNio.85CooaoAlo.osO2） compared with 180.7 mA.h/g of the first discharge capacity and 157.7 mA.h/g of the tenth discharge capacity for LiNiO2, respectively. Differen- tial capacity versus voltage curves showed that the co-doped LiNio.95_xCoxmlo.osO2 had less intensity of the phase transitions than the pristine LiNiO2.
文摘Samples of LiNi0.95-xCoxAl0.05O2（x=0.10 and 0.15） and LiNiO2,synthesized by the solid-state reaction at 725?℃ for 24?h from LiOH·H2O,Ni2O3,Co2O3,and Al（OH）3 under an oxygen stream,were characterized by TG-DTA,XRD,SEM,and electrochemical tests. Simultaneous doping of cobalt and aluminum at the Ni-site in LiNiO2 was tried to improve the cathode performance for lithium-ion batteries. The results showed that co-doping （especially,5% Al and 10% Co in atomic fraction） definitely had a large beneficial effect in increasing the capacity （186.2?mA·h/g of the first discharge capacity for LiNi 0.85 Co 0.1 0Al 0.05 O2） and cycling behavior (180.1?mA·h/g after 10 cycles for LiNi0.95-xCoxAl0.05O2) compared with 180.7?mA·h/g of the first discharge capacity and 157.7?mA·h/g of the tenth discharge capacity for LiNiO2,respectively. Differential capacity versus voltage curves showed that the co-doped LiNi0.95-xCoxAl0.05O2 had less intensity of the phase transitions than the pristine LiNiO2.
基金financial support from the National Natural Science Foundation of China(Grant No.22105106)the Natural Science Foundation of Jiangsu Province of China(Grant No.BK20210603)+1 种基金Nanjing Science and Technology Innovation Project for Overseas Students(Grant No.NJKCZYZZ2022-05)Start-up Funding from NUPTSF(Grant No.NY221003)。
文摘The rapid development of portable and wearable electronic devices is responding to the urgent demand for high-efficiency flexible energy storage devices.Flexible supercapacitors,showing long cycle life,high power density,and good safety,are considered ideal candidates.Nevertheless,the relatively low energy density restricts their practical applications.With a large dielectric constant of 18-46,Ta_(2)O_(5)-based materials typically exhibit excellent electron-binding ability,which is critical for enhancing the energy density of supercapacitors.In this work,the free-standingβ-Ta_(2)O_(5)/single-walled carbon nanotubes(SWCNTs)composite film was prepared,with a highβ-Ta_(2)O_(5)loading of over 70%.By anchoringβ-Ta_(2)O_(5)nanoparticles onto the surface of SWCNTs,the system’s flexibility and conductivity were significantly enhanced,which also facilitated the intercalation electrodynamics of metal cations.As a result,the flexibleβ-Ta_(2)O_(5)/SWCNTs film exhibits excellent Li-ion storage performance,with a high volumetric specific capacitance of 392.3 F cm^(-3)at the scan rate of 10 mV s^(-1)and 198.9 F cm^(-3)at 500 mV s^(-1).In addition,the asymmetric device,assembled by theβ-Ta_(2)O_(5)/SWCNTs and activated carbon films,shows a high energy density of 45.5 Wh kg^(-1)at the power density of 10.8 kW kg^(-1).This technique opens up a new avenue for improving the energy density and rate performance of flexible supercapacitors.
