Objective:To determine lactate dehydrogenase(LDH)level as an indicator of liver,muscular or cancer diseases in patients of more than 40 years of age.Methods:Ninety-one patients(43 females and 48 males)had been tested ...Objective:To determine lactate dehydrogenase(LDH)level as an indicator of liver,muscular or cancer diseases in patients of more than 40 years of age.Methods:Ninety-one patients(43 females and 48 males)had been tested for LDH and liver function tests(LFTs).Creatine kinase(CK)levels were measurement only in patients who had high levels of LDH.Results:As an indicator for liver diseases,high levels of LDH and one or more of LFTs,especially alkaline phosphatase,had been observed in 12 patients(8 females and 4 males).For muscular damage,measurement of CK in patients with elevated levels of LDH and normal levels of LFT revealed that CK values elevated in three males and one female.Whereas high LDH levels,as an indicator for cancer diseases,were found in three males and one female who had normal values of LFTs and CK.Conclusions:LDH can be regarded as a good biomarker for diagnosis of liver,muscular and cancer diseases.There is little variable between males and females in the elevated value of LDH.Patients who had high values of LDH,although they had normal levels of LFTs and CK are proposed to have unidentified cancer disease.展开更多
文摘Objective:To determine lactate dehydrogenase(LDH)level as an indicator of liver,muscular or cancer diseases in patients of more than 40 years of age.Methods:Ninety-one patients(43 females and 48 males)had been tested for LDH and liver function tests(LFTs).Creatine kinase(CK)levels were measurement only in patients who had high levels of LDH.Results:As an indicator for liver diseases,high levels of LDH and one or more of LFTs,especially alkaline phosphatase,had been observed in 12 patients(8 females and 4 males).For muscular damage,measurement of CK in patients with elevated levels of LDH and normal levels of LFT revealed that CK values elevated in three males and one female.Whereas high LDH levels,as an indicator for cancer diseases,were found in three males and one female who had normal values of LFTs and CK.Conclusions:LDH can be regarded as a good biomarker for diagnosis of liver,muscular and cancer diseases.There is little variable between males and females in the elevated value of LDH.Patients who had high values of LDH,although they had normal levels of LFTs and CK are proposed to have unidentified cancer disease.
