Dear Editor, The scarce number of secondary spermatocytes in human seminiferous tubules and the complexity of analyzing chromosomes at metaphase II are the main causes of the limited knowledge we have about chromosom...Dear Editor, The scarce number of secondary spermatocytes in human seminiferous tubules and the complexity of analyzing chromosomes at metaphase II are the main causes of the limited knowledge we have about chromosome characteristics at this stage. In this study, we have performed a comprehensive analysis of meiotic abnormalities in metaphase II spermatocytes combining Leishman＇s staining protocols and multiplex fluorescent in situ hybridization procedures. Results indicated that infertile individuals showed different susceptibilities to meiotic abnormalities in secondary spermatocytes without a preferentially effect on any particular chromosome.展开更多
Dear Editor, In interphase nuclei, chromosomes occupy specific localizations called chromosome territories （CTs）. Distribution of CTs has been related to chromosome size and gene density and is known to influence g...Dear Editor, In interphase nuclei, chromosomes occupy specific localizations called chromosome territories （CTs）. Distribution of CTs has been related to chromosome size and gene density and is known to influence gene expression.~ This pattern of organization appears to be a widespread nuclear feature, both in somatic and germ ceils.展开更多
文摘Dear Editor, The scarce number of secondary spermatocytes in human seminiferous tubules and the complexity of analyzing chromosomes at metaphase II are the main causes of the limited knowledge we have about chromosome characteristics at this stage. In this study, we have performed a comprehensive analysis of meiotic abnormalities in metaphase II spermatocytes combining Leishman＇s staining protocols and multiplex fluorescent in situ hybridization procedures. Results indicated that infertile individuals showed different susceptibilities to meiotic abnormalities in secondary spermatocytes without a preferentially effect on any particular chromosome.
文摘Dear Editor, In interphase nuclei, chromosomes occupy specific localizations called chromosome territories （CTs）. Distribution of CTs has been related to chromosome size and gene density and is known to influence gene expression.~ This pattern of organization appears to be a widespread nuclear feature, both in somatic and germ ceils.
