A number of tetrazoles derivatives were prepared by series of steps, the first step includes react (4,5-dichloroimidazole) with (4-aminoacetophenone) to form 1-(4-((4,5-dichloro-lH-imidazol-2yl)diazenyl)ethan...A number of tetrazoles derivatives were prepared by series of steps, the first step includes react (4,5-dichloroimidazole) with (4-aminoacetophenone) to form 1-(4-((4,5-dichloro-lH-imidazol-2yl)diazenyl)ethanone (1). The second step was (1) reaction with (Amines derivatives) to get Schiff bases (2-7). The third step was reaction of Shciff base with sodiumazide to form tetrazoles derivatives (8-13). then study the biological activity for all compounds to word two type of bacteria.展开更多
文摘A number of tetrazoles derivatives were prepared by series of steps, the first step includes react (4,5-dichloroimidazole) with (4-aminoacetophenone) to form 1-(4-((4,5-dichloro-lH-imidazol-2yl)diazenyl)ethanone (1). The second step was (1) reaction with (Amines derivatives) to get Schiff bases (2-7). The third step was reaction of Shciff base with sodiumazide to form tetrazoles derivatives (8-13). then study the biological activity for all compounds to word two type of bacteria.