One new isobenzofuranone derivative, 1,4-dimethoxy-3-（3R＊-hydroxy-3R＊-methyl-1-tetralone）-1 （3H）-isobenzofuran （1）, was isolated from the broth of marine Streptomyces sp. M268. The structure was elucidated by ...One new isobenzofuranone derivative, 1,4-dimethoxy-3-（3R＊-hydroxy-3R＊-methyl-1-tetralone）-1 （3H）-isobenzofuran （1）, was isolated from the broth of marine Streptomyces sp. M268. The structure was elucidated by spectroscopy characteristics as well as comparison with the literature. Compound 1 exhibited cytotoxicities against human cancer cell, HL-60, A549, and BEL-7402.展开更多
基金supported by the Public Science and Technology Research Funds Projects of Ocean (No.200905021-3)the National Natural Science Foundation of China (No. 31000037)+1 种基金the Key Knowledge Innovation Project of Chinese Academy of Science (No. KZCX2-YW-JC201)the National Science & Technology Pillar Program of China (No. 2011BAE06B004-05)
文摘One new isobenzofuranone derivative, 1,4-dimethoxy-3-（3R＊-hydroxy-3R＊-methyl-1-tetralone）-1 （3H）-isobenzofuran （1）, was isolated from the broth of marine Streptomyces sp. M268. The structure was elucidated by spectroscopy characteristics as well as comparison with the literature. Compound 1 exhibited cytotoxicities against human cancer cell, HL-60, A549, and BEL-7402.
