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Response of runoff and its components to climate change in the Manas River of the Tian Shan Mountains
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作者 ze-long yang Peng BAI 《Advances in Climate Change Research》 SCIE CSCD 2024年第1期62-74,共13页
A warming-wetting climate trend has led to increased runoff in most watersheds in the Tian Shan Mountains over the past few decades.However,it remains unclear how runoff components,that is,rainfall runoff(Rrain),snowm... A warming-wetting climate trend has led to increased runoff in most watersheds in the Tian Shan Mountains over the past few decades.However,it remains unclear how runoff components,that is,rainfall runoff(Rrain),snowmelt runoff(Rsnow),and glacier meltwater(Rglacier),responded to historical climate change and how they will evolve under future climate change scenarios.Here,we used a modified Hydrologiska Byrans Vattenbalansavdelning(HBV)model and a detrending method to quantify the impact of precipitation and temperature changes on runoff components in the largest river(Manas River)on the northern slope of the Tian Shan Mountains from 1982 to 2015.A multivariate calibration strategy,including snow cover,glacier area,and runoff was implemented to constrain model parameters associated with runoff components.The downscaled outputs of 12 general circulation models(GCMs)from the Sixth Coupled Model Intercomparison Project(CMIP6)were also used to force the modified HBV model to project the response of runoff and its components to future(2016-2100)climate change under three common socio-economic pathways(SSP126,SSP245,and SSP585).The results indicate that Rrain dominates mean annual runoff with a proportion of 42%,followed by Rsnow(37%)and Rglacier(21%).In terms of inter-annual variation,Rrain and Rsnow show increasing trends(0.93(p<0.05)and 0.31(p>0.05)mm per year),while Rglacier exhibits an insignificant(p>0.05)decreasing trend(-0.12 mm per year),leading to an increasing trend in total runoff(1.12 mm per year,p>0.05).The attribution analysis indicates that changes in precipitation and temperature contribute 8.16 and 10.37 mm,respectively,to the increase in runoff at the mean annual scale.Climate wetting(increased precipitation)increases Rrain(5.03 mm)and Rsnow(3.19 mm)but has a limited effect on Rglacier(-0.06 mm),while warming increases Rrain(10.69 mm)and Rglacier(5.79 mm)but decreases Rsnow(-6.12 mm).The negative effect of glacier shrinkage on Rglacier has outweighed the positive effect of warming on Rglaciers resulting in the tipping point(peak water)for Rglacier having passed.Runoff projections indicate that future decreases in Rglacier and Rsnow could be offset by increases in Rrain due to increased precipitation projections,reducing the risk of shortages of available water resources.However,management authorities still need to develop adequate adaptation strategies to cope with the continuing decline in Rgacier in the future,considering the large inter-annual fluctuations and high uncertainty in precipitation projection. 展开更多
关键词 Tian Shan Rainfall runoff Snowmelt runoff Glacier meltwater Warming-wetting Tipping point
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新型壳聚糖水凝胶结合软骨细胞修复兔关节软骨缺损的实验研究(英文) 被引量:5
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作者 Ming ZHAO Zhu CHEN +6 位作者 Kang LIU Yu-qing WAN Xu-dong LI Xu-wei LUO Yi-guang BAI ze-long yang Gang FENG 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2015年第11期914-923,共10页
目的:评估壳聚糖水凝胶结合肋软骨细胞构建的新型组织工程软骨对兔关节软骨缺损的修复效果。创新点:利用自主研发的具有良好生物相容性和稳定性的壳聚糖水凝胶与软骨细胞,在体外初步构建组织工程软骨,并尝试利用其修复缺损的关节软... 目的:评估壳聚糖水凝胶结合肋软骨细胞构建的新型组织工程软骨对兔关节软骨缺损的修复效果。创新点:利用自主研发的具有良好生物相容性和稳定性的壳聚糖水凝胶与软骨细胞,在体外初步构建组织工程软骨,并尝试利用其修复缺损的关节软骨,从而为关节软骨缺损的修复提供了一种新的治疗方法。方法:取兔肋软骨体外培养扩增,获得P2代软骨细胞,将其种植到冻干的壳聚糖水凝胶上,体外培养一周,获得初步构建的组织工程软骨。构建兔膝关节软骨缺损模型,并分为3组:实验组植入组织工程软骨;对照组植入壳聚糖水凝胶;空白组不做任何处理。分别于术后4、8和12周取材,通过大体观察、苏木精.伊红染色、番红-O染色及Ⅱ型胶原免疫组化染色等方法观察缺损关节软骨的修复情况,并用国际关节软骨修复协会(ICRS)制定的评分法进行大体及组织学评分。结论:兔肋软骨细胞能在实验室自主构建的壳聚糖水凝胶上增殖并分泌细胞外基质(图2),植入到兔关节软骨缺损处后,对缺损关节软骨具有良好的修复作用(图3和5),且修复是一种完全的结构性的修复(图5~7)。 展开更多
关键词 关节软骨修复 组织工程软骨 壳聚糖水凝胶
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Risk factors of portal vein thrombosis after splenectomy in patients with liver cirrhosis 被引量:2
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作者 ze-long yang Ting Guo +3 位作者 Dong-Lie Zhu Shi Zheng Dan-Dan Han Yong Chen 《Hepatoma Research》 2020年第7期1-13,共13页
Portal vein thrombosis(PVT)is a common complication after splenectomy,causing a possible negative impact on the prognosis of patients with liver cirrhosis.However,the risk factors of PVT are not completely clear.Many ... Portal vein thrombosis(PVT)is a common complication after splenectomy,causing a possible negative impact on the prognosis of patients with liver cirrhosis.However,the risk factors of PVT are not completely clear.Many factors are related to the occurrence of postoperative PVT,such as hemodynamic changes,splenomegaly,splenectomy,coagulation and anticoagulation disorder,liver cirrhosis,platelet count,D-dimer level,infection,inflammation,and other factors.Hemodynamic changes are mainly caused by thicker portal and splenic vein diameters,larger spleen,slower portal vein blood flow rate,lower portal vein pressure before and after surgery,etc.It is timely detection and advanced prevention that really matter in reducing PVT incidence and improving patient prognosis.We systematically reviewed the researches on the risk factors and therapies of PVTto provide useful information on a comprehensive understanding for researchers. 展开更多
关键词 Liver cirrhosis SPLENECTOMY portal vein thrombosis risk factors TREATMENTS PROPHYLAXIS
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