Dear Editor,COVID-19(Coronavirus Disease 2019)is causing an unprecedented public health crisis.Protein translation is crucial for virus lifecycle.Nucleocapsid(N)protein is among the most abundant SARS-CoV-2 proteins a...Dear Editor,COVID-19(Coronavirus Disease 2019)is causing an unprecedented public health crisis.Protein translation is crucial for virus lifecycle.Nucleocapsid(N)protein is among the most abundant SARS-CoV-2 proteins and highly conserved across coronavirus genus.1 However,its function in subverting host translation machinery is still elusive.展开更多
基金National Key Research and Development Program of China,Stem Cell and Translation Research[2018YFA0109300 to P.Q.]National Natural Science Foundation of China[82222003,81870080,91949115,82161138028 to P.Q.+3 种基金31900815 to H.W.]Natural Science Foundation of Zhejiang Province[LR19H080001 to P.Q.]Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang[2020R01006 to P.Q.]Zhejiang Provincial Key Research and Development Program[2021C03043 to H.Y.].We are grateful to W.P.H.(Shandong University)for providing original SARS-CoV-2 protein expressing plasmids.
文摘Dear Editor,COVID-19(Coronavirus Disease 2019)is causing an unprecedented public health crisis.Protein translation is crucial for virus lifecycle.Nucleocapsid(N)protein is among the most abundant SARS-CoV-2 proteins and highly conserved across coronavirus genus.1 However,its function in subverting host translation machinery is still elusive.