目的:探讨大剂量阿托伐他汀联合阿替普酶对急性脑梗死患者血清炎症因子及神经功能的影响。方法:选取2017年3月至2021年3月广西医科大学附属武鸣医院收治的急性脑梗死患者196例作为研究对象。通过随机数字表法,患者被分为观察组和对照组...目的:探讨大剂量阿托伐他汀联合阿替普酶对急性脑梗死患者血清炎症因子及神经功能的影响。方法:选取2017年3月至2021年3月广西医科大学附属武鸣医院收治的急性脑梗死患者196例作为研究对象。通过随机数字表法,患者被分为观察组和对照组。观察组98例患者的治疗方式为大剂量阿托伐他汀联合阿替普酶,对照组98例患者的治疗方式为大剂量阿托伐他汀联合尿激酶。观察两组患者的临床疗效,治疗前后美国国立卫生院卒中神经功能缺损评分量表(national institutes of health stroke scale,NIHSS)评分、日常生活活动(activity of daily living,ADL)评分,总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)及高密度脂蛋白胆固醇(HDL-C)水平,血清肿瘤坏死因子α(TNF-α)、超敏C反应蛋白(hs-CRP)和基质金属蛋白酶9(MMP-9)水平。结果:观察组患者的总有效率为95.92%(94/98),对照组患者的总有效率为91.84%(90/98),两组比较,差异无统计学意义(P>0.05)。治疗42 d后,两组患者的NIHSS评分较治疗前明显降低,且观察组患者明显更低;两组患者的ADL评分较治疗前明显升高,且观察组患者明显更高,上述差异均有统计学意义(P<0.05)。两组患者治疗42 d后的TC、TG和LDL-C水平较治疗前明显更低,HDL-C水平较治疗前明显更高,差异均有统计学意义(P<0.05);两组患者治疗42 d后的TC、TG、LDL-C和HDL-C比较,差异均无统计学意义(P>0.05)。两组患者治疗42 d后的TNF-α、hs-CRP和MMP-9水平较治疗前明显降低,且观察组患者的降低程度较对照组明显更大,差异均有统计学意义(P<0.05)。结论:与大剂量阿托伐他汀联合尿激酶相比,大剂量阿托伐他汀联合阿替普酶在改善急性脑梗死患者神经功能损伤、恢复日常生活能力和降低炎症反应方面更具优势。展开更多
The Forum on China-Africa Cooperation （FOCAC） is an effective platform and multilateral mechanism for China and African countries to conduct collective consultations and carry out pragmatic cooperation. Since its es...The Forum on China-Africa Cooperation （FOCAC） is an effective platform and multilateral mechanism for China and African countries to conduct collective consultations and carry out pragmatic cooperation. Since its establishment in 2000, six ministerial conferences, convened every three years, have been successfully held so far. Chinese and African cities have been taking turns to host the conferences. Beijing was the host city of the first （2000）, third （2006） and fifth （2012） ministerial conferences.展开更多
Major changes unseen in a century are taking place in our world,and the COVID-19 pandemic has even accelerated this process.Global governance faces a real test of multipolarity versus unipolarity,openness versus isola...Major changes unseen in a century are taking place in our world,and the COVID-19 pandemic has even accelerated this process.Global governance faces a real test of multipolarity versus unipolarity,openness versus isolation,and cooperation versus confrontation.With the changing international landscape,the fourth session of the 13th National People’s Congress in March 2021 adopted the Outline of the 14th Five-Year Plan(2021-2025)for National Economic and Social Development and the Long-Range Objectives Through the Year 2035.With a long-term and holistic perspective,the Outline echoes China’s pursuit of high-quality Belt and Road cooperation.1 This requires China and other countries to empower the Belt and Road cooperation,among which there is a pressing need for global health governance cooperation.When COVID-19 as a once-in-a-century health crisis broke out at the beginning of 2020,we human beings have once again witnessed how ruthless a disease can be and how precious lives are.Therefore,building the Health Silk Road is in urgent need and of particular significance during the pandemic.展开更多
文摘目的:探讨大剂量阿托伐他汀联合阿替普酶对急性脑梗死患者血清炎症因子及神经功能的影响。方法:选取2017年3月至2021年3月广西医科大学附属武鸣医院收治的急性脑梗死患者196例作为研究对象。通过随机数字表法,患者被分为观察组和对照组。观察组98例患者的治疗方式为大剂量阿托伐他汀联合阿替普酶,对照组98例患者的治疗方式为大剂量阿托伐他汀联合尿激酶。观察两组患者的临床疗效,治疗前后美国国立卫生院卒中神经功能缺损评分量表(national institutes of health stroke scale,NIHSS)评分、日常生活活动(activity of daily living,ADL)评分,总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)及高密度脂蛋白胆固醇(HDL-C)水平,血清肿瘤坏死因子α(TNF-α)、超敏C反应蛋白(hs-CRP)和基质金属蛋白酶9(MMP-9)水平。结果:观察组患者的总有效率为95.92%(94/98),对照组患者的总有效率为91.84%(90/98),两组比较,差异无统计学意义(P>0.05)。治疗42 d后,两组患者的NIHSS评分较治疗前明显降低,且观察组患者明显更低;两组患者的ADL评分较治疗前明显升高,且观察组患者明显更高,上述差异均有统计学意义(P<0.05)。两组患者治疗42 d后的TC、TG和LDL-C水平较治疗前明显更低,HDL-C水平较治疗前明显更高,差异均有统计学意义(P<0.05);两组患者治疗42 d后的TC、TG、LDL-C和HDL-C比较,差异均无统计学意义(P>0.05)。两组患者治疗42 d后的TNF-α、hs-CRP和MMP-9水平较治疗前明显降低,且观察组患者的降低程度较对照组明显更大,差异均有统计学意义(P<0.05)。结论:与大剂量阿托伐他汀联合尿激酶相比,大剂量阿托伐他汀联合阿替普酶在改善急性脑梗死患者神经功能损伤、恢复日常生活能力和降低炎症反应方面更具优势。
文摘The Forum on China-Africa Cooperation （FOCAC） is an effective platform and multilateral mechanism for China and African countries to conduct collective consultations and carry out pragmatic cooperation. Since its establishment in 2000, six ministerial conferences, convened every three years, have been successfully held so far. Chinese and African cities have been taking turns to host the conferences. Beijing was the host city of the first （2000）, third （2006） and fifth （2012） ministerial conferences.
文摘Major changes unseen in a century are taking place in our world,and the COVID-19 pandemic has even accelerated this process.Global governance faces a real test of multipolarity versus unipolarity,openness versus isolation,and cooperation versus confrontation.With the changing international landscape,the fourth session of the 13th National People’s Congress in March 2021 adopted the Outline of the 14th Five-Year Plan(2021-2025)for National Economic and Social Development and the Long-Range Objectives Through the Year 2035.With a long-term and holistic perspective,the Outline echoes China’s pursuit of high-quality Belt and Road cooperation.1 This requires China and other countries to empower the Belt and Road cooperation,among which there is a pressing need for global health governance cooperation.When COVID-19 as a once-in-a-century health crisis broke out at the beginning of 2020,we human beings have once again witnessed how ruthless a disease can be and how precious lives are.Therefore,building the Health Silk Road is in urgent need and of particular significance during the pandemic.
