目的推动印刷行业朝更高效的方向迈进,提高印刷设备的易操作性和视觉识别性。方法将Kano和FAST(Function Analysis System Technique)模型引入瓦楞纸激光打印设备设计的前期应用需求分析中,通过问卷的方法获取用户的基本要求,并划分为...目的推动印刷行业朝更高效的方向迈进,提高印刷设备的易操作性和视觉识别性。方法将Kano和FAST(Function Analysis System Technique)模型引入瓦楞纸激光打印设备设计的前期应用需求分析中,通过问卷的方法获取用户的基本要求,并划分为几个子类型,进而建立Kano的二维功能属性模型。采用FAST法建立功能树,辅助使用Kano模型,从而更精准地分析用户需求,并更好地根据其需求进行优化设计。结果综合运用设计原理,针对性地挖掘瓦楞纸激光印刷设备在造型识别性、操作易用性、生产安全性上存在的问题,进而输出更优解。结论该设计方法的引入有助于为同类型的印刷设备设计提供参考,并引起更多相关厂家的重视,推动印刷行业向更积极的方向发展。展开更多
目的观察补阳还五汤(BYHW)对过氧化氢(H_(2)O_(2))诱导的衰老内皮细胞沉默信息调节因子1(silent information regulator 1,SIRT1)-自噬通路的作用。方法以人脐静脉内皮细胞(HUVEC)作为研究对象,H_(2)O_(2)诱导的内皮细胞作为模型,体外培...目的观察补阳还五汤(BYHW)对过氧化氢(H_(2)O_(2))诱导的衰老内皮细胞沉默信息调节因子1(silent information regulator 1,SIRT1)-自噬通路的作用。方法以人脐静脉内皮细胞(HUVEC)作为研究对象,H_(2)O_(2)诱导的内皮细胞作为模型,体外培养HUVECs,并将细胞分为正常组、模型组(H_(2)O_(2)400μmol/L)、BYHW组(H_(2)O_(2)400μmol/L+BYHW 2500μg/mL)。衰老相关β半乳糖苷酶(SA-β-Gal)染色检测细胞衰老,蛋白质免疫印迹法检测SIRT1、纤溶酶原激活物抑制因子1(PAI-1)、泛素结合蛋白p62及微管相关蛋白1轻链3β(LC3)蛋白的表达,ELISA法检测细胞上清液中超氧化物歧化酶(superoxide dismutase,SOD)、丙二醛(malondialdehyde,MDA)含量,免疫荧光观察SIRT1、LC3的表达。结果400μmol/L的H_(2)O_(2)处理可成功诱导HUVECs衰老。与正常组相比,衰老模型组中SA-β-Gal阳染率增加,SIRT1、LC3蛋白表达降低,SOD含量降低,PAI-1、p62蛋白表达升高,MDA含量升高,细胞免疫荧光显示SIRT1、LC3表达降低。与模型组比较,BYHW组细胞蓝染比率降低,PAI-1、p62蛋白表达降低,SOD水平升高,SIRT1、LC3蛋白表达升高,细胞免疫荧光BYHW组SIRT1、LC3表达明显升高。结论在过氧化氢诱导的HUVECs衰老模型中,补阳还五汤能够上调SIRT1,激活自噬,从而对衰老的内皮细胞起到保护作用。展开更多
As the unmanned weap system-of systems(UWSoS)becomes complex,the inevitable uncertain interference gradu-ally increases,which leads to a strong emphasis on the resilience of UWSoS.Hence,this paper presents a resilienc...As the unmanned weap system-of systems(UWSoS)becomes complex,the inevitable uncertain interference gradu-ally increases,which leads to a strong emphasis on the resilience of UWSoS.Hence,this paper presents a resilience-driven cooperative reconfiguration strategy to enhance the resilience of UWSoS.First,a unified resilience-driven coopera-tive reconfiguration strategy framework is designed to guide the UWSoS resilience enhancement.Subsequently,a cooperative reconfiguration strategy algorithm is proposed to identify the optimal cooperative reconfiguration sequence,combining the cooperative pair resilience contribution index(CPRCI)and coop-erative pair importance index(CPII).At last,the effectiveness and superiority of the proposed algorithm are demonstrated through various attack scenario simulations that include differ-ent attack modes and intensities.The analysis results can pro-vide a reference for decision-makers to manage UWSoS.展开更多
文摘目的推动印刷行业朝更高效的方向迈进,提高印刷设备的易操作性和视觉识别性。方法将Kano和FAST(Function Analysis System Technique)模型引入瓦楞纸激光打印设备设计的前期应用需求分析中,通过问卷的方法获取用户的基本要求,并划分为几个子类型,进而建立Kano的二维功能属性模型。采用FAST法建立功能树,辅助使用Kano模型,从而更精准地分析用户需求,并更好地根据其需求进行优化设计。结果综合运用设计原理,针对性地挖掘瓦楞纸激光印刷设备在造型识别性、操作易用性、生产安全性上存在的问题,进而输出更优解。结论该设计方法的引入有助于为同类型的印刷设备设计提供参考,并引起更多相关厂家的重视,推动印刷行业向更积极的方向发展。
基金This work was supported by Ph.D.Intelligent Innovation Foundation Project(201-CXCY-A01-08-19-01)Science and Technology on Information System Engineering Laboratory(05202007).
文摘As the unmanned weap system-of systems(UWSoS)becomes complex,the inevitable uncertain interference gradu-ally increases,which leads to a strong emphasis on the resilience of UWSoS.Hence,this paper presents a resilience-driven cooperative reconfiguration strategy to enhance the resilience of UWSoS.First,a unified resilience-driven coopera-tive reconfiguration strategy framework is designed to guide the UWSoS resilience enhancement.Subsequently,a cooperative reconfiguration strategy algorithm is proposed to identify the optimal cooperative reconfiguration sequence,combining the cooperative pair resilience contribution index(CPRCI)and coop-erative pair importance index(CPII).At last,the effectiveness and superiority of the proposed algorithm are demonstrated through various attack scenario simulations that include differ-ent attack modes and intensities.The analysis results can pro-vide a reference for decision-makers to manage UWSoS.