Over the recent past,fluoroquinolone antibiotics(FQs)have raised extensive attention due to their potential to induce the formation of resistance genes and"superbugs",thus various advanced oxidation techniqu...Over the recent past,fluoroquinolone antibiotics(FQs)have raised extensive attention due to their potential to induce the formation of resistance genes and"superbugs",thus various advanced oxidation techniques have been developed to eliminate their release into the environment.In the present study,the prototype tetraamido macrocyclic ligand(Fe^Ⅲ-TAML)/hydrogen peroxide(H2O_(2))system is employed to degrade FQs(i.e.,norfloxacin and ciprofloxacin)over a wide p H range(i.e.,p H 6-10),and the reaction rate increases with the increase in p H level.The effect of dosage of Fe^Ⅲ-TAML and H2O_(2) on the degradation of FQs is evaluated,and the reaction rate is linearly correlated with the added amount of chemicals.Moreover,the impact of natural organic matters(NOM)on the removal of FQs is investigated,and the degradation kinetics show that both NOM type and experimental concentration exhibit negligible influence on the oxidative degradation of selected antibiotics.Based on the results of liquid chromatography-high resolution mass spectrometry and theoretical calculations,the reaction sites and pathways of FQs by Fe^Ⅲ-TAML/H2O_(2) system are further predicted and elucidated.展开更多
基金financially supported by the National Key Research and Development Plans of Special Project for Site Soil(No.2018YFC1802003)the National Science Foundation of China(Nos.21906079,21777066 and 41703090)the Natural Science Foundation of Jiangsu Province of China(No.BK20170634)。
文摘Over the recent past,fluoroquinolone antibiotics(FQs)have raised extensive attention due to their potential to induce the formation of resistance genes and"superbugs",thus various advanced oxidation techniques have been developed to eliminate their release into the environment.In the present study,the prototype tetraamido macrocyclic ligand(Fe^Ⅲ-TAML)/hydrogen peroxide(H2O_(2))system is employed to degrade FQs(i.e.,norfloxacin and ciprofloxacin)over a wide p H range(i.e.,p H 6-10),and the reaction rate increases with the increase in p H level.The effect of dosage of Fe^Ⅲ-TAML and H2O_(2) on the degradation of FQs is evaluated,and the reaction rate is linearly correlated with the added amount of chemicals.Moreover,the impact of natural organic matters(NOM)on the removal of FQs is investigated,and the degradation kinetics show that both NOM type and experimental concentration exhibit negligible influence on the oxidative degradation of selected antibiotics.Based on the results of liquid chromatography-high resolution mass spectrometry and theoretical calculations,the reaction sites and pathways of FQs by Fe^Ⅲ-TAML/H2O_(2) system are further predicted and elucidated.
