Wearable biosensors,which aim at providing continuous,real-time physiological information via monitoring and screening biomarkers in human body,are receiving increasing attention among various fields including dis-eas...Wearable biosensors,which aim at providing continuous,real-time physiological information via monitoring and screening biomarkers in human body,are receiving increasing attention among various fields including dis-ease treatment,diagnosis and self-health management.The ongoing development in this realm starves for the exploration of fully-integrated,non-invasive devices.In this paper,we review the latest achievements with break-through significance on the wearable biosensors.We start with the classification of different types of wearable electronic devices and analyze their characteristics and application values.Subsequently,we introduce a fully-integrated microneedle-based sensor and provide an in-depth look at its structure,subcomponents and in vivo performances.Finally,we put forward critical commentaries and clarify the direction of future researches.展开更多
基金supported by the National Natural Science Foun-dation of China(Grant 82102511)the Natural Science Foundation of Jiangsu(Grants BK20210021 and BK20210010)Research Project of Jiangsu Province Health Committee(Grant M2021031).
文摘Wearable biosensors,which aim at providing continuous,real-time physiological information via monitoring and screening biomarkers in human body,are receiving increasing attention among various fields including dis-ease treatment,diagnosis and self-health management.The ongoing development in this realm starves for the exploration of fully-integrated,non-invasive devices.In this paper,we review the latest achievements with break-through significance on the wearable biosensors.We start with the classification of different types of wearable electronic devices and analyze their characteristics and application values.Subsequently,we introduce a fully-integrated microneedle-based sensor and provide an in-depth look at its structure,subcomponents and in vivo performances.Finally,we put forward critical commentaries and clarify the direction of future researches.