智慧伊春时空信息云平台常态化运行与应用趋势探索

智慧伊春时空信息云平台项目建设的意义在于构建统一权威的智慧伊春时空信息基础设施,进而推动智慧城市建设,促进数据交换与共享,破解城市难题,提升治理能力。本文针对智慧伊春时空信息云平台,分析常态化运行的关键问题,对应用趋势和发展方向进行探索,为科学评价和持续发展提供参考。

双重领导体制下黑龙江应急测绘保障体系建设与运营机制探讨

随着国家机构改革的深入和职责日益清晰,完成好“国家应急测绘保障能力建设”重大项目,将职能与任务结合,做好国家、省级双向应急测绘保障工作,是应急测绘保障体系建设的核心任务。本文梳理了黑龙江应急测绘保障体系建设的三大核心,对运营机制进行探讨,可为双重领导体制下的应急测绘保障体系建设发展提供参考。

Point Cloud Classification and Accuracy Analysis Based on Feature Fusion

A method for land-cover classification was proposed based on the fusion of features generated from waveform data and point cloud respectively.It aims to partially overcome the ineffectiveness of many traditional classifiers caused by the fact that point cloud is lacking spectral information.The whole flowchart of the method is as follows:Firstly,Gaussian decomposition was applied to fit an echo full-waveform.The parameters associated with the Gaussian function were optimized by LM(Levenberg-Marquard)algorithm.Six and thirteen features were generated to describe the waveform characteristics and the local geometry of point cloud,respectively.Secondly,a random forest was selected as the classifier to which the generated features were input.Relief-F was used to rank the weights of all the features generated.Finally,features were input to the classifier one by one according to the weights calculated from feature ranking,where classification accuracies were evaluated.The experimental results show that the effectiveness of the fusion of features generated from waveform and point cloud for LiDAR data classification,with 95.4%overall accuracy,0.90 kappa coefficient,which outperform the results obtained by a single class of features,no matter whether they were generated from point cloud or waveform data.

土槿乙酸C-18醇酯衍生物的合成及其体外免疫抑制活性研究

目的:将土瑾乙酸C-18位进行结构改造,筛选出具有高效、低毒、水溶性好等优点的新型免疫抑制化合物。方法:将C-18位还原为醇羟基,通过缩合酰化反应引入苯环、呋喃环、吡啶环羧酸,得到土槿乙酸C-18醇酯衍生物。经MTT法对小鼠T、B淋巴细胞的免疫抑制活性和对小鼠正常脾细胞毒性体外细胞实验筛选。结果:合成得到10个未见文献报道的土瑾乙酸C-18醇酯衍生物B1-B10,所合成的目标化合物均经~1H-NMR, ^(13)C-NMR, HR-ESI进行结构确定,并测定了其体外免疫抑制活性,结果显示其中衍生物B2、B6、B7对T淋巴细胞增殖抑制活性强于土槿乙酸,衍生物B6、B7对B淋巴细胞抑制活性明显强于土槿乙酸。尤其是大多数化合物对正常细胞作用很弱,远低于阳性对照药,呈现高效低毒特性。结论:土槿乙酸C-18醇酯衍生物,引入呋喃环,抑制T、B淋巴细胞增殖活性明显增加,引入具有共轭体系的呋喃环时活性更佳,并且毒性降低。