目的系统评价坦索罗辛联合丁溴东莨菪碱在泌尿系结石体外冲击波碎石(ESWL)后辅助排石的效果及安全性。方法计算机检索中国知网、万方、VIP、CBM、PubMed、Cochrane Library、Web of Science核心合集数据库,检索时限从建库至2022年4月,...目的系统评价坦索罗辛联合丁溴东莨菪碱在泌尿系结石体外冲击波碎石(ESWL)后辅助排石的效果及安全性。方法计算机检索中国知网、万方、VIP、CBM、PubMed、Cochrane Library、Web of Science核心合集数据库,检索时限从建库至2022年4月,查找坦索罗辛联合丁溴东莨菪碱辅助ESWL治疗泌尿系结石的随机对照试验,试验组ESWL后给予坦索罗辛+丁溴东莨菪碱,对照组ESWL后给予丁溴东莨菪碱。采用RevMan 5.4软件进行meta分析,分析两组有效率、排石时间、肾绞痛消失时间、疼痛评分及不良反应情况,其中根据排石时间单位选择分为小时组、天数组;根据评分量表选择分为视觉模拟评分法(VAS)组、数字疼痛评分法(NPRS)组。结果共纳入8篇文献,1762例患者。试验组有效率高于对照组(RR=1.21,95%CI:1.16,1.26,P<0.00001)。小时组排石时间短于对照组(SMD=-5.50,95%CI:-6.59,-4.41,P<0.00001)。天数组排石时间短于对照组(SMD=-4.21,95%CI:-6.40,-2.03,P=0.0002)。试验组肾绞痛消失时间短于对照组(SMD=-2.04,95%CI:-2.18,-1.91,P<0.00001)。VAS组疼痛程度低于对照组(SMD=-0.65,95%CI:-0.90,-0.39,P<0.00001)。NPRS组疼痛程度低于对照组(SMD=-1.59,95%CI:-1.80,-1.38,P<0.00001)。两组不良反应比较,差异无统计学意义(P>0.05)。结论坦索罗辛联合丁溴东莨菪碱辅助ESWL治疗泌尿系结石可以提高治疗的有效率,促进结石排出、缩短疼痛时间及减轻患者疼痛症状,是一种安全有效的方法。展开更多
The year 2017 marked not only the 45th anniversary of the establishment of China-Australia diplomatic relations,but also significant turbulence in the relationship.While bilateral economic and trade relations,as well ...The year 2017 marked not only the 45th anniversary of the establishment of China-Australia diplomatic relations,but also significant turbulence in the relationship.While bilateral economic and trade relations,as well as people-to-people communication and cooperation continue to grow,a series of dramatic and negative events unfolded in Australia,advocating the so-called"China threat",and instigated by anti-China sentiments.The recent anti-China backlash in Australia was caused by a combination of deep structural change in the current international system,and instability in Australia’s domestic politics.It is also the outcome of Australia’s dependence on the US-Australia alliance,while balancing between its own economic and security interests.It is worth noting that in comparison to the past,the current anti-China movement in Australia has been more profound and more focused,demonstrating new characteristics.This includes Australia collaborating with certain Western nations against China’s influence,as well as strategic warnings with more political and policy implications.Although Australia’s anti-China backlash will not have a fundamental impact on China-Australia relations,Australia’s anti-China stance and behavior is characteristic of an increasingly prevalent trend among the Western nations of concern about China’s rising influence,and new defense strategies against this.China must proceed with caution when dealing with the negative repercussions of this.展开更多
文摘目的系统评价坦索罗辛联合丁溴东莨菪碱在泌尿系结石体外冲击波碎石(ESWL)后辅助排石的效果及安全性。方法计算机检索中国知网、万方、VIP、CBM、PubMed、Cochrane Library、Web of Science核心合集数据库,检索时限从建库至2022年4月,查找坦索罗辛联合丁溴东莨菪碱辅助ESWL治疗泌尿系结石的随机对照试验,试验组ESWL后给予坦索罗辛+丁溴东莨菪碱,对照组ESWL后给予丁溴东莨菪碱。采用RevMan 5.4软件进行meta分析,分析两组有效率、排石时间、肾绞痛消失时间、疼痛评分及不良反应情况,其中根据排石时间单位选择分为小时组、天数组;根据评分量表选择分为视觉模拟评分法(VAS)组、数字疼痛评分法(NPRS)组。结果共纳入8篇文献,1762例患者。试验组有效率高于对照组(RR=1.21,95%CI:1.16,1.26,P<0.00001)。小时组排石时间短于对照组(SMD=-5.50,95%CI:-6.59,-4.41,P<0.00001)。天数组排石时间短于对照组(SMD=-4.21,95%CI:-6.40,-2.03,P=0.0002)。试验组肾绞痛消失时间短于对照组(SMD=-2.04,95%CI:-2.18,-1.91,P<0.00001)。VAS组疼痛程度低于对照组(SMD=-0.65,95%CI:-0.90,-0.39,P<0.00001)。NPRS组疼痛程度低于对照组(SMD=-1.59,95%CI:-1.80,-1.38,P<0.00001)。两组不良反应比较,差异无统计学意义(P>0.05)。结论坦索罗辛联合丁溴东莨菪碱辅助ESWL治疗泌尿系结石可以提高治疗的有效率,促进结石排出、缩短疼痛时间及减轻患者疼痛症状,是一种安全有效的方法。
基金financial support from the Young Faculty Research Fund of Beijing Foreign Studies University(2015JT003)
文摘The year 2017 marked not only the 45th anniversary of the establishment of China-Australia diplomatic relations,but also significant turbulence in the relationship.While bilateral economic and trade relations,as well as people-to-people communication and cooperation continue to grow,a series of dramatic and negative events unfolded in Australia,advocating the so-called"China threat",and instigated by anti-China sentiments.The recent anti-China backlash in Australia was caused by a combination of deep structural change in the current international system,and instability in Australia’s domestic politics.It is also the outcome of Australia’s dependence on the US-Australia alliance,while balancing between its own economic and security interests.It is worth noting that in comparison to the past,the current anti-China movement in Australia has been more profound and more focused,demonstrating new characteristics.This includes Australia collaborating with certain Western nations against China’s influence,as well as strategic warnings with more political and policy implications.Although Australia’s anti-China backlash will not have a fundamental impact on China-Australia relations,Australia’s anti-China stance and behavior is characteristic of an increasingly prevalent trend among the Western nations of concern about China’s rising influence,and new defense strategies against this.China must proceed with caution when dealing with the negative repercussions of this.
