为深入探索老山芹种子休眠机理,以老山芹层积前后种子为研究对象,采用气相色谱-飞行时间质谱联用技术(gas chromatography-time of flight mass spectrometry,GC-TOF/MS)对其非层积种子(non-lamellarized seeds,NS)和层积后达到发芽状...为深入探索老山芹种子休眠机理,以老山芹层积前后种子为研究对象,采用气相色谱-飞行时间质谱联用技术(gas chromatography-time of flight mass spectrometry,GC-TOF/MS)对其非层积种子(non-lamellarized seeds,NS)和层积后达到发芽状态种子(germination seeds,GS)的差异代谢物进行分析。结果表明,共检测到995种代谢产物,NS和GS的代谢物存在明显分离,差异代谢物有126种,其中极显著差异代谢物75种,包括35种上调,40种下调。对极显著差异代谢物所在代谢通路分析表明,涉及10条关键代谢通路。和弦图分析表明,差异代谢物中脂质类化合物(含类脂分子)与苯类化合物呈极显著正相关;苯丙烷类化合物(含聚酮类化合物)与有机氧类化合物呈极显著负相关。以上研究结果为探索老山芹种子成熟后萌发提供了代谢组学理论基础,为更好地研究老山芹种子后成熟及休眠机制提供了依据和支撑。展开更多
以大轴端面锈蚀为清洗目标,采用模块化设计方法,利用Visual Studio 2017开发环境下的MFC框架开发基于视觉的激光清洗软件系统,设计图像综合、程序管理、清洗工艺管理和报警监测四大功能模块。利用该软件系统进行相关测试,结果表明:该软...以大轴端面锈蚀为清洗目标,采用模块化设计方法,利用Visual Studio 2017开发环境下的MFC框架开发基于视觉的激光清洗软件系统,设计图像综合、程序管理、清洗工艺管理和报警监测四大功能模块。利用该软件系统进行相关测试,结果表明:该软件系统各模块运行稳定,管理便捷,可视化程度高,能够满足大轴端面锈蚀的激光清洗功能需求。展开更多
A strong electric (E) field sounding system was designed to measure the vertical component of the E-fields, temperature, relative humidity and GPS data along the sounding path. In the summer of 2008, in situ measureme...A strong electric (E) field sounding system was designed to measure the vertical component of the E-fields, temperature, relative humidity and GPS data along the sounding path. In the summer of 2008, in situ measurements of E-field inside the thunderstorms were conducted in Pingliang, Gansu Provience, with the cooperation of an X-band weather radar. One E-field profile inside a thunderstorm was successfully acquired. The sounding data indicated four charge layers along the sounding trajectory, three in-side the thuderstorm and one at its lower boundary. The lower cloud boundary charge layer was negative, acting as a screening layer, and laid between 4.3 to 4.5 km a.s.l. The lower positive charge center (LPCC) existed between 4.5–5.3 km a.s.l. (from 3°C to -2°C); the main negative charge area was present between 5.4–6.6 km a.s.l. (-3°C to -10°C); the upper positive charge layer was between 6.7–7.2 km a.s.l. (-11°C to -14°C). The results support the tripole charge structure inside thunderstorms (above 0°C isotherm altitude), but the LPCC is much larger-than-usual in Chinese inland plateau.展开更多
Considering the issues of energy saving and environment protection,the performance of refrigeration systems requires to be improved.In recent years,nano-fluids have attracted greatly attention from the researchers due...Considering the issues of energy saving and environment protection,the performance of refrigeration systems requires to be improved.In recent years,nano-fluids have attracted greatly attention from the researchers due to their outstanding thermal characteristics.In this work,the published investigations on the preparation and characterization of nano-fluids have been discussed at first.Furthermore,the key thermo-physical properties of nano-fluids,such as thermal conductivity,viscosity,specific heat and density have been summarized.Finally,the performance enhancements in different types of refrigeration systems by using nano-fluids have been reviewed.It is concluded that nano-fluids as refrigerant,lubricant or secondary fluid have wide potential application in refrigeration systems.展开更多
目的应用meta分析明确5-羟色胺2A受体(5-HTR2A)基因rs6311(-1438A>G)和rs6313(102T>C)位点多态性与抗精神分裂症药物疗效的相关性。方法计算机检索PubMed、Embase、ScienceDirect、Web of Science和中国知网、万方、维普、中国生...目的应用meta分析明确5-羟色胺2A受体(5-HTR2A)基因rs6311(-1438A>G)和rs6313(102T>C)位点多态性与抗精神分裂症药物疗效的相关性。方法计算机检索PubMed、Embase、ScienceDirect、Web of Science和中国知网、万方、维普、中国生物医学文献数据库,获取近20年有关5-HTR2A基因多态性与抗精神分裂症药物疗效关系的相关文献,提取数据。采用Review Manager 5.3软件进行meta分析。结果共纳入27篇文献。分别对5-HTR2A基因rs6311、rs6313位点的等位基因和基因型多态性与抗精神分裂症药物治疗有效率、减分率的关联性进行meta分析,并以时间、药物、地区3种因素分别进行亚组分析。rs6311位点有效率数据合并显示,等位基因A>G多态性与抗精神病药疗效无关,而亚组分析显示中国人群中等位基因A患者的有效率更高;减分率数据合并显示AG基因型患者的抗精神病药物减分率高于GG。对于rs6313位点,等位基因T>C多态性与抗精神病药有效率无关,而与基因型多态性存在关联,TC基因型患者的氯丙嗪有效率高于TT基因型患者;减分率数据也显示TC患者的药物减分率比TT患者高,亚组分析显示在中国群体中基因型TC患者减分率高于TT患者,而其他国家群体中CC基因型患者减分率高于TT患者,在利培酮和1999—2009群体中TC基因型患者的减分率均高于CC基因型患者。结论5-HTR2A基因多态性与抗精神分裂症药物疗效的关联受时间、药物、地区的影响,但总体而言rs6311位点AG基因型、rs6313位点TC基因型是抗精神分裂症药物疗效好的预测因子。展开更多
文摘为深入探索老山芹种子休眠机理,以老山芹层积前后种子为研究对象,采用气相色谱-飞行时间质谱联用技术(gas chromatography-time of flight mass spectrometry,GC-TOF/MS)对其非层积种子(non-lamellarized seeds,NS)和层积后达到发芽状态种子(germination seeds,GS)的差异代谢物进行分析。结果表明,共检测到995种代谢产物,NS和GS的代谢物存在明显分离,差异代谢物有126种,其中极显著差异代谢物75种,包括35种上调,40种下调。对极显著差异代谢物所在代谢通路分析表明,涉及10条关键代谢通路。和弦图分析表明,差异代谢物中脂质类化合物(含类脂分子)与苯类化合物呈极显著正相关;苯丙烷类化合物(含聚酮类化合物)与有机氧类化合物呈极显著负相关。以上研究结果为探索老山芹种子成熟后萌发提供了代谢组学理论基础,为更好地研究老山芹种子后成熟及休眠机制提供了依据和支撑。
文摘以大轴端面锈蚀为清洗目标,采用模块化设计方法,利用Visual Studio 2017开发环境下的MFC框架开发基于视觉的激光清洗软件系统,设计图像综合、程序管理、清洗工艺管理和报警监测四大功能模块。利用该软件系统进行相关测试,结果表明:该软件系统各模块运行稳定,管理便捷,可视化程度高,能够满足大轴端面锈蚀的激光清洗功能需求。
基金supported by the National Natural Science Foundation of China (Grant No. 40675008) Knowledge Innovation Project of Chinese Academy of Sciences (Grant No. KZCX2-YW-206)Hundred Tal-ents Program of CAS
文摘A strong electric (E) field sounding system was designed to measure the vertical component of the E-fields, temperature, relative humidity and GPS data along the sounding path. In the summer of 2008, in situ measurements of E-field inside the thunderstorms were conducted in Pingliang, Gansu Provience, with the cooperation of an X-band weather radar. One E-field profile inside a thunderstorm was successfully acquired. The sounding data indicated four charge layers along the sounding trajectory, three in-side the thuderstorm and one at its lower boundary. The lower cloud boundary charge layer was negative, acting as a screening layer, and laid between 4.3 to 4.5 km a.s.l. The lower positive charge center (LPCC) existed between 4.5–5.3 km a.s.l. (from 3°C to -2°C); the main negative charge area was present between 5.4–6.6 km a.s.l. (-3°C to -10°C); the upper positive charge layer was between 6.7–7.2 km a.s.l. (-11°C to -14°C). The results support the tripole charge structure inside thunderstorms (above 0°C isotherm altitude), but the LPCC is much larger-than-usual in Chinese inland plateau.
基金National Natural Science Foundation of China(No.51906013)The Pyramid Talent Training Project of Beijing University of Civil Engineering and Architecture,China(JDYC20200316)。
文摘Considering the issues of energy saving and environment protection,the performance of refrigeration systems requires to be improved.In recent years,nano-fluids have attracted greatly attention from the researchers due to their outstanding thermal characteristics.In this work,the published investigations on the preparation and characterization of nano-fluids have been discussed at first.Furthermore,the key thermo-physical properties of nano-fluids,such as thermal conductivity,viscosity,specific heat and density have been summarized.Finally,the performance enhancements in different types of refrigeration systems by using nano-fluids have been reviewed.It is concluded that nano-fluids as refrigerant,lubricant or secondary fluid have wide potential application in refrigeration systems.
文摘目的应用meta分析明确5-羟色胺2A受体(5-HTR2A)基因rs6311(-1438A>G)和rs6313(102T>C)位点多态性与抗精神分裂症药物疗效的相关性。方法计算机检索PubMed、Embase、ScienceDirect、Web of Science和中国知网、万方、维普、中国生物医学文献数据库,获取近20年有关5-HTR2A基因多态性与抗精神分裂症药物疗效关系的相关文献,提取数据。采用Review Manager 5.3软件进行meta分析。结果共纳入27篇文献。分别对5-HTR2A基因rs6311、rs6313位点的等位基因和基因型多态性与抗精神分裂症药物治疗有效率、减分率的关联性进行meta分析,并以时间、药物、地区3种因素分别进行亚组分析。rs6311位点有效率数据合并显示,等位基因A>G多态性与抗精神病药疗效无关,而亚组分析显示中国人群中等位基因A患者的有效率更高;减分率数据合并显示AG基因型患者的抗精神病药物减分率高于GG。对于rs6313位点,等位基因T>C多态性与抗精神病药有效率无关,而与基因型多态性存在关联,TC基因型患者的氯丙嗪有效率高于TT基因型患者;减分率数据也显示TC患者的药物减分率比TT患者高,亚组分析显示在中国群体中基因型TC患者减分率高于TT患者,而其他国家群体中CC基因型患者减分率高于TT患者,在利培酮和1999—2009群体中TC基因型患者的减分率均高于CC基因型患者。结论5-HTR2A基因多态性与抗精神分裂症药物疗效的关联受时间、药物、地区的影响,但总体而言rs6311位点AG基因型、rs6313位点TC基因型是抗精神分裂症药物疗效好的预测因子。
