CFSFDP(Clustering by fast search and find of density peak)is a simple and crisp density clustering algorithm.It does not only have the advantages of density clustering algorithm,but also can find the peak of cluster a...CFSFDP(Clustering by fast search and find of density peak)is a simple and crisp density clustering algorithm.It does not only have the advantages of density clustering algorithm,but also can find the peak of cluster automatically.However,the lack of adaptability makes it difficult to apply in intrusion detection.The new input cannot be updated in time to the existing profiles,and rebuilding profiles would waste a lot of time and computation.Therefore,an adaptive anomaly detection algorithm based on CFSFDP is proposed in this paper.By analyzing the influence of new input on center,edge and discrete points,the adaptive problem mainly focuses on processing with the generation of new cluster by new input.The improved algorithm can integrate new input into the existing clustering without changing the original profiles.Meanwhile,the improved algorithm takes the advantage of multi-core parallel computing to deal with redundant computing.A large number of experiments on intrusion detection on Android platform and KDDCUP 1999 show that the improved algorithm can update the profiles adaptively without affecting the original detection performance.Compared with the other classical algorithms,the improved algorithm based on CFSFDP has the good basic performance and more room of improvement.展开更多
Summary What is already known about this topic?People are likely to engage in collective behaviors online during extreme events,such as the coronavirus disease 2019(COVID-19)crisis,to express awareness,take action,and...Summary What is already known about this topic?People are likely to engage in collective behaviors online during extreme events,such as the coronavirus disease 2019(COVID-19)crisis,to express awareness,take action,and work through concerns.展开更多
The rapid emergence and widespread transmission of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)have prompted governments worldwide to enact policies and measures to manage the virus’s spread.These inte...The rapid emergence and widespread transmission of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)have prompted governments worldwide to enact policies and measures to manage the virus’s spread.These interventions have substantially contributed to controlling disease transmission.However,they have also significantly disrupted daily life,leading to increased public fatigue and resistance to sustained control measures,a phenomenon known as pandemic fatigue.To develop a comprehensive understanding of pandemic fatigue,this review systematically explores the concept and identifies quantitative indicators for measuring it.We reviewed studies on pandemic fatigue across various countries,summarized the contributing factors,and analyzed its impact on personal protective behaviors.Our findings indicate that the enforcement of health measures significantly influences the onset of pandemic fatigue,while individual perceptions of risk can negatively affect personal protective behaviors,creating a feedback loop with increasing fatigue.These results underscore the importance of considering the current severity of the pandemic and individual decisionmaking processes in the implementation of interventions.Enhancing our understanding of pandemic fatigue is essential for developing effective policy responses in preparation for future potential epidemics.展开更多
Wearing masks is an easy way to operate and popular measure for preventing epidemics.Although masks can slow down the spread of viruses,their efficacy in gathering environments involving heterogeneous person-to-person...Wearing masks is an easy way to operate and popular measure for preventing epidemics.Although masks can slow down the spread of viruses,their efficacy in gathering environments involving heterogeneous person-to-person contacts remains unknown.Therefore,we aim to investigate the epidemic prevention effect of masks in different real-life gathering environments.This study uses four real interpersonal contact datasets to construct four empirical networks to represent four gathering environments.The transmission of COVID-19 is simulated using the Monte Carlo simulation method.The heterogeneity of individuals can cause mask efficacy in a specific gathering environment to be different from the baseline efficacy in general society.Furthermore,the heterogeneity of gathering environments causes the epidemic prevention effect of masks to differ.Wearing masks can greatly reduce the probability of clustered epidemics and the infection scale in primary schools,high schools,and hospitals.However,the use of masks alone in primary schools and hospitals cannot control outbreaks.In high schools with social distancing between classes and in workplaces where the interpersonal contact is relatively sparse,masks can meet the need for prevention.Given the heterogeneity of individual behavior,if individuals who are more active in terms of interpersonal contact are prioritized for mask-wearing,the epidemic prevention effect of masks can be improved.Finally,asymptomatic infection has varying effects on the prevention effect of masks in different environments.The effect can be weakened or eliminated by increasing the usage rate of masks in high schools and workplaces.However,the effect on primary schools and hospitals cannot be weakened.This study contributes to the accurate evaluation of mask efficacy in various gathering environments to provide scientific guidance for epidemic prevention.展开更多
Background:Seasonal influenza resurged in China in February 2023,causing a large number of hospitalizations.While influenza epidemics occurred across China during the coronavirus disease 2019(COVID-19)pandemic,the rel...Background:Seasonal influenza resurged in China in February 2023,causing a large number of hospitalizations.While influenza epidemics occurred across China during the coronavirus disease 2019(COVID-19)pandemic,the relaxation of COVID-19 containment measures in December 2022 may have contributed to the spread of acute respiratory infections in winter 2022/2023.Methods:Using a mathematical model incorporating influenza activity as measured by influenza-like illness(ILI)data for northern and southern regions of China,we reconstructed the seasonal influenza incidence from October 2015 to September 2019 before the COVID-19 pandemic.Using this trained model,we predicted influenza activities in northern and southern China from March to September 2023.Results:We estimated the effective reproduction number Re as 1.08[95%confidence interval(CI):0.51,1.65]in northern China and 1.10(95%CI:0.55,1.67)in southern China at the start of the 2022-2023 influenza season.We estimated the infection attack rate of this influenza wave as 18.51%(95%CI:0.00%,37.78%)in northern China and 28.30%(95%CI:14.77%,41.82%)in southern China.Conclusions:The 2023 spring wave of seasonal influenza in China spread until July 2023 and infected a substantial number of people.展开更多
Introduction:Minimizing the importation and exportation risks of coronavirus disease 2019(COVID-19)is a primary concern for sustaining the“Dynamic COVID-zero”strategy in China.Risk estimation is essential for cities...Introduction:Minimizing the importation and exportation risks of coronavirus disease 2019(COVID-19)is a primary concern for sustaining the“Dynamic COVID-zero”strategy in China.Risk estimation is essential for cities to conduct before relaxing border control measures.Methods:Informed by the daily number of passengers traveling between 367 prefectures(cities)in China,this study used a stochastic metapopulation model parameterized with COVID-19 epidemic characteristics to estimate the importation and exportation risks.Results:Under the transmission scenario(R0=5.49),this study estimated the cumulative case incidence of Changchun City,Jilin Province as 3,233(95%confidence interval:1,480,4,986)before a lockdown on March 14,2022,which is close to the 3,168 cases reported in real life by March 16,2022.In a total of 367 prefectures(cities),127(35%)had high exportation risks according to the simulation and could transmit the disease to 50%of all other regions within a period from 17 to 94 days.The average time until a new infection arrives in a location in 1 of the 367 prefectures(cities)ranged from 26 to 101 days.Conclusions:Estimating COVID-19 importation and exportation risks is necessary for preparedness,prevention,and control measures of COVID-19—especially when new variants emerge.展开更多
Introduction:The ease of coronavirus disease 2019(COVID-19)non-pharmacological interventions and the increased susceptibility during the past COVID-19 pandemic could be a precursor for the resurgence of influenza,pote...Introduction:The ease of coronavirus disease 2019(COVID-19)non-pharmacological interventions and the increased susceptibility during the past COVID-19 pandemic could be a precursor for the resurgence of influenza,potentially leading to a severe outbreak in the winter of 2022 and future seasons.The recent increased availability of data on Electronic Health Records(EHR)in public health systems,offers new opportunities to monitor individuals to mitigate outbreaks.Methods:We introduced a new methodology to rank individuals for surveillance in temporal networks,which was more practical than the static networks.By targeting previously infected nodes,this method used readily available EHR data instead of the contactnetwork structure.Results:We validated this method qualitatively in a real-world cohort study and evaluated our approach quantitatively by comparing it to other surveillance methods on three temporal and empirical networks.We found that,despite not explicitly exploiting the contacts’network structure,it remained the best or close to the best strategy.We related the performance of the method to the public health goals,the reproduction number of the disease,and the underlying temporal-network structure(e.g.,burstiness).Discussion:The proposed strategy of using historical records for sentinel surveillance selection can be taken as a practical and robust alternative without the knowledge of individual contact behaviors for public health policymakers.展开更多
基金supported in part by the National Key Research and Development Program of China under Grant No.2018YFB1800303the Science and Technology Planning Project of Jilin Province under Grant No.20190302070GXthe Science and Technology Projects of Jilin Provincial Education Department(the 13th five year plan)under Grant Nos.JJKH20190593KJ,JJKH20190546KJ,and JJKH20200795KJ.
文摘CFSFDP(Clustering by fast search and find of density peak)is a simple and crisp density clustering algorithm.It does not only have the advantages of density clustering algorithm,but also can find the peak of cluster automatically.However,the lack of adaptability makes it difficult to apply in intrusion detection.The new input cannot be updated in time to the existing profiles,and rebuilding profiles would waste a lot of time and computation.Therefore,an adaptive anomaly detection algorithm based on CFSFDP is proposed in this paper.By analyzing the influence of new input on center,edge and discrete points,the adaptive problem mainly focuses on processing with the generation of new cluster by new input.The improved algorithm can integrate new input into the existing clustering without changing the original profiles.Meanwhile,the improved algorithm takes the advantage of multi-core parallel computing to deal with redundant computing.A large number of experiments on intrusion detection on Android platform and KDDCUP 1999 show that the improved algorithm can update the profiles adaptively without affecting the original detection performance.Compared with the other classical algorithms,the improved algorithm based on CFSFDP has the good basic performance and more room of improvement.
文摘Summary What is already known about this topic?People are likely to engage in collective behaviors online during extreme events,such as the coronavirus disease 2019(COVID-19)crisis,to express awareness,take action,and work through concerns.
基金Supported by the National Key R&D Program of China(No.2022YFE0112300)the Shenzhen-Hong Kong-Macao Science and Technology Project(Category C)(Project no:SGDX20230821091559022)+2 种基金the National Natural Science Foundation of China(grant no.72104208)the General Research Fund(grant no.17103122)from the Research Grants Council,and the Health and Medical Research Fund(grant no.21200632)along with the HMRF Research Fellowship Scheme(grant no.07210147)both financed by the Food and Health Bureau of the Government of Hong Kong S.A.R.,China.
文摘The rapid emergence and widespread transmission of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)have prompted governments worldwide to enact policies and measures to manage the virus’s spread.These interventions have substantially contributed to controlling disease transmission.However,they have also significantly disrupted daily life,leading to increased public fatigue and resistance to sustained control measures,a phenomenon known as pandemic fatigue.To develop a comprehensive understanding of pandemic fatigue,this review systematically explores the concept and identifies quantitative indicators for measuring it.We reviewed studies on pandemic fatigue across various countries,summarized the contributing factors,and analyzed its impact on personal protective behaviors.Our findings indicate that the enforcement of health measures significantly influences the onset of pandemic fatigue,while individual perceptions of risk can negatively affect personal protective behaviors,creating a feedback loop with increasing fatigue.These results underscore the importance of considering the current severity of the pandemic and individual decisionmaking processes in the implementation of interventions.Enhancing our understanding of pandemic fatigue is essential for developing effective policy responses in preparation for future potential epidemics.
基金This work was supported by the National Natural Science Foundation of China(Grant Nos.62173065,11875005,61976025,and 11975025)the University Synergy Innovation Program of Anhui Province(Grant No.GXXT-2021-032)+1 种基金the Natural Science Foundation of Liaoning Province(Grant No.2020-MZLH-22)Major Project of the National Social Science Fund of China(Grant No.19ZDA324).
文摘Wearing masks is an easy way to operate and popular measure for preventing epidemics.Although masks can slow down the spread of viruses,their efficacy in gathering environments involving heterogeneous person-to-person contacts remains unknown.Therefore,we aim to investigate the epidemic prevention effect of masks in different real-life gathering environments.This study uses four real interpersonal contact datasets to construct four empirical networks to represent four gathering environments.The transmission of COVID-19 is simulated using the Monte Carlo simulation method.The heterogeneity of individuals can cause mask efficacy in a specific gathering environment to be different from the baseline efficacy in general society.Furthermore,the heterogeneity of gathering environments causes the epidemic prevention effect of masks to differ.Wearing masks can greatly reduce the probability of clustered epidemics and the infection scale in primary schools,high schools,and hospitals.However,the use of masks alone in primary schools and hospitals cannot control outbreaks.In high schools with social distancing between classes and in workplaces where the interpersonal contact is relatively sparse,masks can meet the need for prevention.Given the heterogeneity of individual behavior,if individuals who are more active in terms of interpersonal contact are prioritized for mask-wearing,the epidemic prevention effect of masks can be improved.Finally,asymptomatic infection has varying effects on the prevention effect of masks in different environments.The effect can be weakened or eliminated by increasing the usage rate of masks in high schools and workplaces.However,the effect on primary schools and hospitals cannot be weakened.This study contributes to the accurate evaluation of mask efficacy in various gathering environments to provide scientific guidance for epidemic prevention.
基金Supported by grants from the AIR@InnoHK Programme of the Innovation and Technology Commission of the Government of the Hong Kong Special Administrative Region and the Theme-based Research Scheme(T11-712/19-N)of the Research Grants Council of the Hong Kong SAR Government.
文摘Background:Seasonal influenza resurged in China in February 2023,causing a large number of hospitalizations.While influenza epidemics occurred across China during the coronavirus disease 2019(COVID-19)pandemic,the relaxation of COVID-19 containment measures in December 2022 may have contributed to the spread of acute respiratory infections in winter 2022/2023.Methods:Using a mathematical model incorporating influenza activity as measured by influenza-like illness(ILI)data for northern and southern regions of China,we reconstructed the seasonal influenza incidence from October 2015 to September 2019 before the COVID-19 pandemic.Using this trained model,we predicted influenza activities in northern and southern China from March to September 2023.Results:We estimated the effective reproduction number Re as 1.08[95%confidence interval(CI):0.51,1.65]in northern China and 1.10(95%CI:0.55,1.67)in southern China at the start of the 2022-2023 influenza season.We estimated the infection attack rate of this influenza wave as 18.51%(95%CI:0.00%,37.78%)in northern China and 28.30%(95%CI:14.77%,41.82%)in southern China.Conclusions:The 2023 spring wave of seasonal influenza in China spread until July 2023 and infected a substantial number of people.
基金Supported by AIR@InnoHK programme from The Innovation and Technology Commission of the Hong Kong Special Administrative Region,National Natural Science Foundation of China(72104208)JSPS KAKENHI(JP21H04595)National Nature Science Foundation of China(72025405,91846301,72088101,and 71790615).
文摘Introduction:Minimizing the importation and exportation risks of coronavirus disease 2019(COVID-19)is a primary concern for sustaining the“Dynamic COVID-zero”strategy in China.Risk estimation is essential for cities to conduct before relaxing border control measures.Methods:Informed by the daily number of passengers traveling between 367 prefectures(cities)in China,this study used a stochastic metapopulation model parameterized with COVID-19 epidemic characteristics to estimate the importation and exportation risks.Results:Under the transmission scenario(R0=5.49),this study estimated the cumulative case incidence of Changchun City,Jilin Province as 3,233(95%confidence interval:1,480,4,986)before a lockdown on March 14,2022,which is close to the 3,168 cases reported in real life by March 16,2022.In a total of 367 prefectures(cities),127(35%)had high exportation risks according to the simulation and could transmit the disease to 50%of all other regions within a period from 17 to 94 days.The average time until a new infection arrives in a location in 1 of the 367 prefectures(cities)ranged from 26 to 101 days.Conclusions:Estimating COVID-19 importation and exportation risks is necessary for preparedness,prevention,and control measures of COVID-19—especially when new variants emerge.
基金Supported by Key Projects of Intergovernmental International Scientific and Technological Innovation Cooperation of National Key R&D Programs(No.2022YFE0112300)AIR@InnoHK administered by Innovation and Technology Commission of the Research Grants Council of the Hong Kong SAR Government。
文摘Introduction:The ease of coronavirus disease 2019(COVID-19)non-pharmacological interventions and the increased susceptibility during the past COVID-19 pandemic could be a precursor for the resurgence of influenza,potentially leading to a severe outbreak in the winter of 2022 and future seasons.The recent increased availability of data on Electronic Health Records(EHR)in public health systems,offers new opportunities to monitor individuals to mitigate outbreaks.Methods:We introduced a new methodology to rank individuals for surveillance in temporal networks,which was more practical than the static networks.By targeting previously infected nodes,this method used readily available EHR data instead of the contactnetwork structure.Results:We validated this method qualitatively in a real-world cohort study and evaluated our approach quantitatively by comparing it to other surveillance methods on three temporal and empirical networks.We found that,despite not explicitly exploiting the contacts’network structure,it remained the best or close to the best strategy.We related the performance of the method to the public health goals,the reproduction number of the disease,and the underlying temporal-network structure(e.g.,burstiness).Discussion:The proposed strategy of using historical records for sentinel surveillance selection can be taken as a practical and robust alternative without the knowledge of individual contact behaviors for public health policymakers.