To discuss the current and future financial development and risk prevention,population as a long-term,systematic, and irreversible factor, should be taken into careful consideration.As for China,we should pay particul...To discuss the current and future financial development and risk prevention,population as a long-term,systematic, and irreversible factor, should be taken into careful consideration.As for China,we should pay particular attention to the situation of rapid ageing and urbanization in the next 20 years,which would result in profound influence on this issue.To achieve coordinated development of population,resources and the environment,to prioritize investment in human development,and to set up a whole system and mechanism for addressing population issue,should be our policy choices now and in the future.展开更多
Using cDNA microarray hybridization from a human testicular cDNA library, one gene exhibiting ten-fold difference at expression level between adult and embryo human testes was cloned and named NYD-SP9, which was belie...Using cDNA microarray hybridization from a human testicular cDNA library, one gene exhibiting ten-fold difference at expression level between adult and embryo human testes was cloned and named NYD-SP9, which was believed to be involved in spermatogenesis. Southern blot hybridization results showed that NYD-SP9 expressed highly in testis but low in ovary. Protein motif analysis of this cDNA sequence revealed a cluster of phosphorylation sites, indicating its potential involvement in signal pathways during spermatogenesis. Furthermore, one transmembrane helix was predicted in N-terminal region, indicating that putative NYD-SP6 may be served as a transmembrane protein. The proximity of these potential phosphorylation sites to each other indicates that there may be interaction among these sites to regulate spermatogenesis. These findings suggested that protein kinase NYD-SP9 might play a role in male germ cell differentiation.展开更多
文摘To discuss the current and future financial development and risk prevention,population as a long-term,systematic, and irreversible factor, should be taken into careful consideration.As for China,we should pay particular attention to the situation of rapid ageing and urbanization in the next 20 years,which would result in profound influence on this issue.To achieve coordinated development of population,resources and the environment,to prioritize investment in human development,and to set up a whole system and mechanism for addressing population issue,should be our policy choices now and in the future.
基金This work was supported by the State "973" Fund (Grant No. G1999055901).
文摘Using cDNA microarray hybridization from a human testicular cDNA library, one gene exhibiting ten-fold difference at expression level between adult and embryo human testes was cloned and named NYD-SP9, which was believed to be involved in spermatogenesis. Southern blot hybridization results showed that NYD-SP9 expressed highly in testis but low in ovary. Protein motif analysis of this cDNA sequence revealed a cluster of phosphorylation sites, indicating its potential involvement in signal pathways during spermatogenesis. Furthermore, one transmembrane helix was predicted in N-terminal region, indicating that putative NYD-SP6 may be served as a transmembrane protein. The proximity of these potential phosphorylation sites to each other indicates that there may be interaction among these sites to regulate spermatogenesis. These findings suggested that protein kinase NYD-SP9 might play a role in male germ cell differentiation.
