目的:探讨丹红注射液联合依达拉奉注射液治疗进展性缺血性脑卒中的疗效。方法:采用回顾性分析的方式,将2015年7月至2016年8月十堰市太和医院收治的63例进展性缺血性脑卒中患者设为对照组,将2016年9月至2017年9月收治的64例进展性缺血性...目的:探讨丹红注射液联合依达拉奉注射液治疗进展性缺血性脑卒中的疗效。方法:采用回顾性分析的方式,将2015年7月至2016年8月十堰市太和医院收治的63例进展性缺血性脑卒中患者设为对照组,将2016年9月至2017年9月收治的64例进展性缺血性脑卒中患者设为观察组。两组患者均接受脑卒中单元个体化治疗2周,观察组患者在对照组的基础上加用丹红注射液+依达拉奉注射液静脉滴注。监测两组患者局部脑血流(RCBF),比较两组患者血液流变学指标、血脂代谢指标、血清可溶性细胞间黏附分子-1(sICAM-1)和血管细胞黏附分子-1(VCAM-1)水平的差异,观察两组患者日常生活能力(activity of daily living,ADL)评分、美国国立卫生院卒中神经功能缺损评分量表(national institutes of health stroke scale,NIHSS)评分及临床疗效。结果:治疗1、2周,观察组患者的RCBF明显高于对照组,差异均有统计学意义(P<0.05);治疗后,观察组患者的纤维蛋白原、血小板聚集率、全血高切黏度、全血低切黏度和红细胞比容明显低于对照组,差异均有统计学意义(P<0.05);治疗后,观察组患者的三酰甘油、总胆固醇及低密度脂蛋白胆固醇水平明显低于对照组,而高密度脂蛋白胆固醇水平明显高于对照组,差异均有统计学意义(P<0.05);治疗后,观察组患者sICAM-1和VCAM-1水平明显低于对照组,差异均有统计学意义(P<0.05);治疗2周和随访3个月时,观察组患者ADL评分明显高于对照组,NIHSS评分明显低于对照组,差异均有统计学意义(P<0.05);观察组患者的总有效率为75.00%(48/64),明显高于对照组的65.08%(41/63),差异有统计学意义(P<0.05)。结论:丹红注射液联合依达拉奉注射液治疗进展性缺血性脑卒中的疗效显著,有利于降低患者血液黏性和血脂水平,增加RCBF,改善微循环,并促进神经功能恢复。展开更多
The one-step hydrotreatment of rubber seed oil to produce hydrocarbon fuels has been carried out via supported Pd-catalyst,and analyzed emphatically some elements affected catalytic cracking process,for example,temper...The one-step hydrotreatment of rubber seed oil to produce hydrocarbon fuels has been carried out via supported Pd-catalyst,and analyzed emphatically some elements affected catalytic cracking process,for example,temperature,hydrogen partial pressure and dosage of catalyst,etc.Through experimental research,the author found out the appropriate catalytic cracking conditions as follows:310℃ of reaction temperature,2 MPa of hydrogen partial pressure,15 of the ratio of oil to catalyst(m(oil)/m(catalyst)),100 r/min of stirring speed.Under these conditions,effective component of hydrocarbon fuels in the converted oil accounts for 99.49%,and the proportion of C_(8)-C_(16) can reach as high as 79.61%.The converted oil was similar to petroleum-based oil in chemical composition,and can be used for future the aviation biofuels development as the source of raw material because it contains a large amount of hydrocarbon in the range of C_(8)-C_(16).展开更多
文摘目的:探讨丹红注射液联合依达拉奉注射液治疗进展性缺血性脑卒中的疗效。方法:采用回顾性分析的方式,将2015年7月至2016年8月十堰市太和医院收治的63例进展性缺血性脑卒中患者设为对照组,将2016年9月至2017年9月收治的64例进展性缺血性脑卒中患者设为观察组。两组患者均接受脑卒中单元个体化治疗2周,观察组患者在对照组的基础上加用丹红注射液+依达拉奉注射液静脉滴注。监测两组患者局部脑血流(RCBF),比较两组患者血液流变学指标、血脂代谢指标、血清可溶性细胞间黏附分子-1(sICAM-1)和血管细胞黏附分子-1(VCAM-1)水平的差异,观察两组患者日常生活能力(activity of daily living,ADL)评分、美国国立卫生院卒中神经功能缺损评分量表(national institutes of health stroke scale,NIHSS)评分及临床疗效。结果:治疗1、2周,观察组患者的RCBF明显高于对照组,差异均有统计学意义(P<0.05);治疗后,观察组患者的纤维蛋白原、血小板聚集率、全血高切黏度、全血低切黏度和红细胞比容明显低于对照组,差异均有统计学意义(P<0.05);治疗后,观察组患者的三酰甘油、总胆固醇及低密度脂蛋白胆固醇水平明显低于对照组,而高密度脂蛋白胆固醇水平明显高于对照组,差异均有统计学意义(P<0.05);治疗后,观察组患者sICAM-1和VCAM-1水平明显低于对照组,差异均有统计学意义(P<0.05);治疗2周和随访3个月时,观察组患者ADL评分明显高于对照组,NIHSS评分明显低于对照组,差异均有统计学意义(P<0.05);观察组患者的总有效率为75.00%(48/64),明显高于对照组的65.08%(41/63),差异有统计学意义(P<0.05)。结论:丹红注射液联合依达拉奉注射液治疗进展性缺血性脑卒中的疗效显著,有利于降低患者血液黏性和血脂水平,增加RCBF,改善微循环,并促进神经功能恢复。
基金This work was supported by the National Natural Science Foundation of China(No.21266032)International S&T Cooperation Program of China(No.2015DFA60120).
文摘The one-step hydrotreatment of rubber seed oil to produce hydrocarbon fuels has been carried out via supported Pd-catalyst,and analyzed emphatically some elements affected catalytic cracking process,for example,temperature,hydrogen partial pressure and dosage of catalyst,etc.Through experimental research,the author found out the appropriate catalytic cracking conditions as follows:310℃ of reaction temperature,2 MPa of hydrogen partial pressure,15 of the ratio of oil to catalyst(m(oil)/m(catalyst)),100 r/min of stirring speed.Under these conditions,effective component of hydrocarbon fuels in the converted oil accounts for 99.49%,and the proportion of C_(8)-C_(16) can reach as high as 79.61%.The converted oil was similar to petroleum-based oil in chemical composition,and can be used for future the aviation biofuels development as the source of raw material because it contains a large amount of hydrocarbon in the range of C_(8)-C_(16).
