Myeloid sarcoma with maxillary gingival swell

BACKGROUND Myeloid sarcoma(MS),also referred to as granulocytic sarcoma or chloroma,is a rare type of extramedullary malignant tumor.MS comprises primitive granulocytic precursor cells that play a key role in the early stages of white blood cell development.Notably,the occurrence of this tumor in the gingiva is rare.CASE SUMMARY The present study reported the case of MS with gingival swelling in the maxillary region,with aleukemic presentation in a 32-year-old male patient.Following two courses of chemotherapy,computed tomography of the region demonstrated complete clearance of the tumor.At the 12-month follow-up appointment,the patient was in a stable condition with the absence of progression.The etiology,clinical features,diagnosis,and relevant treatment of MS are discussed in the present study.CONCLUSION Diagnosis of MS may be confirmed following histological and immunohistochemical examinations.

Clinical Characteristics and Treatment of Spontaneous Osteonecrosis of Medial Tibial Plateau： A Retrospective Case Study

Background： In a small proportion of cases, spontaneous osteonecrosis of the knee （SONK） involves the medial tibial plateau （MT）. Here, we introduced the clinical characteristics of spontaneous osteonecrosis of the MT and unicompartmental knee arthroplasty （UKA） as the favorable treatment for this situation based on a retrospective case study. Methods： Patients with spontaneous osteonecrosis of the MT, confirmed by magnetic resonance imaging （MRI） at Guangdong Provincial Hospital of Chinese Medicine （China） from March 2015 to June 2016, were included as a case serial and analyzed retrospectively. All patients underwent Oxford Medial UKA. The characteristics of their lesions, corresponding treatment, and results of follow-up were presented. The lesion scores and grade were determined according to the criteria of Ficat and Arlet. Results： In total, 22 patients （5 men, 17 women： mean age, 64.1 years） with spontaneous osteonecrosis of the MT were analyzed. The lesion stages assessment showed that 3 （14%） were Stage 11, 10 （45%） were Stage Ⅲ, 7 （32%） were Stage IV, and 2 （9%） were Stage V. In the sagittal plane, 7 （32%） were in the anterior region （MTa） and 15 （68%） were central （MTc）. The lesion volume averaged 2.24 ± 0.79 cm3 （range： 1.57-3.08 cm3）. Seventeen patients （77%） had Level Ⅲ posterior medial meniscus root tears （MM RTs）. All the patients underwent UKA. Average follow-up was 30.0 ± 6.4 months with a range of 23.0-38.0 months. The visual analog scale score was 7.78 ± 0.67 belbre surgery while decreased to 2.22 ± 1.09 at the final follow-up （P 〈 0.001 ）. The Hospital for Special Surgery scores of pre-/post-surgery were 65.67 ± 5.45 and 84.10 ± 4.20, respectively （P 〈 0.001 ）. Conclusions： SONK often occurs in the anterior and central tibial plateau due to abnormal stresses. Most of the patients had Level Ⅲ posterior medial meniscus root tears. MRI is recommended for suspected cases to identity SONK at an early stage. The use of the Oxford Medial UKA for SONK of the MT is reliable both immediately and at follow-up.