Pituitary adenylate cyclase-activating polypeptide (PACAP) has been shown to posses mitogenic activity in some carcinomatic cells and normal cells. The present study was designed to investigate the growth modulation o...Pituitary adenylate cyclase-activating polypeptide (PACAP) has been shown to posses mitogenic activity in some carcinomatic cells and normal cells. The present study was designed to investigate the growth modulation of PACAP on three kinds of human pancreas carcinoma cell strains (JF305, HS766T and ASPC-l) and its pathways of postreceptor signal transduction, role of sphingomyelin as a second messenger.展开更多
文摘Pituitary adenylate cyclase-activating polypeptide (PACAP) has been shown to posses mitogenic activity in some carcinomatic cells and normal cells. The present study was designed to investigate the growth modulation of PACAP on three kinds of human pancreas carcinoma cell strains (JF305, HS766T and ASPC-l) and its pathways of postreceptor signal transduction, role of sphingomyelin as a second messenger.
