[Objectives] To investigate the infrared identification of ZhuQin Formula and Atractylodes polysaccharides and its effect on immune function in immunocompromised mice. [Methods] In this experiment,the structure of pol...[Objectives] To investigate the infrared identification of ZhuQin Formula and Atractylodes polysaccharides and its effect on immune function in immunocompromised mice. [Methods] In this experiment,the structure of polysaccharides was analyzed by Fourier transform infrared spectroscopy. The experiment was divided into the polysaccharide groups of high,medium and low dose of ZhuQin,the extraction group of ZhuQin,the polysaccharide group of Atractylodes,the positive drug group,the blank group and the model group. The model of immunosuppressed mice was established by intraperitoneal injection of cyclophosphamide. The carbon clearance index,immune organ index,serum hemolysin,spleen T and B lymphocyte transformation rate were determined. [Results]The results show that the polysaccharides have obvious absorption peaks of polysaccharides; Formula extracts and polysaccharides can enhance the immune function of immunosuppressive mice at a certain dose level,and the effect of formula polysaccharide is better than that of extract and single traditional Chinese medicine polysaccharides. [Conclusions] The results suggest that the polysaccharides of ZhuQin Formula and Atractylodes may be acidic polysaccharides containing pyran ring and furan ring. ZhuQin Formula polysaccharide may play an immunomodulatory role mainly by improving the specific immunity of the organism.展开更多
Because of the global warming and the increasing human activity, the air temperature and the precipitation along the Qinghai-Tibet Railway increased gradually in recent years, which endanger the permafrost table, the ...Because of the global warming and the increasing human activity, the air temperature and the precipitation along the Qinghai-Tibet Railway increased gradually in recent years, which endanger the permafrost table, the embankment of the railway. The statistics of the air temperature, the precipitation and the geothermal temperature in recent 50 years in this dissertation come from the four weather station along the railway, that are Wudaoliang Station, Fenghuo Mountains Sta- tion, Tuotuo River Station and Ando Station. This dissertation analyzes the change of climate along the railway and then develops a research on the effect of the changing geothermal temperature on permafrost table and its countermeasures. The experiment result shows that the air temperature of the permafrost region rise steadily in about 50 years, especially in this century, the tendency of rising temperature is more obvious. The precipitation fluctuates but it is also rising rapidly, for the largest precipitation reached 492.6 mm. For 30 years now, the Qinghai-Tibet Plateau has been in the megathermal period, which also affects the permafrost region along the railway. The condition of permafrost is degrading greatly.展开更多
基金Supported by Public Welfare and Industry Special Fund Project of the Ministry of Agriculture(201303040-05)Natural Science Foundation Project of CQCSTC(2013FYF110600)
文摘[Objectives] To investigate the infrared identification of ZhuQin Formula and Atractylodes polysaccharides and its effect on immune function in immunocompromised mice. [Methods] In this experiment,the structure of polysaccharides was analyzed by Fourier transform infrared spectroscopy. The experiment was divided into the polysaccharide groups of high,medium and low dose of ZhuQin,the extraction group of ZhuQin,the polysaccharide group of Atractylodes,the positive drug group,the blank group and the model group. The model of immunosuppressed mice was established by intraperitoneal injection of cyclophosphamide. The carbon clearance index,immune organ index,serum hemolysin,spleen T and B lymphocyte transformation rate were determined. [Results]The results show that the polysaccharides have obvious absorption peaks of polysaccharides; Formula extracts and polysaccharides can enhance the immune function of immunosuppressive mice at a certain dose level,and the effect of formula polysaccharide is better than that of extract and single traditional Chinese medicine polysaccharides. [Conclusions] The results suggest that the polysaccharides of ZhuQin Formula and Atractylodes may be acidic polysaccharides containing pyran ring and furan ring. ZhuQin Formula polysaccharide may play an immunomodulatory role mainly by improving the specific immunity of the organism.
文摘Because of the global warming and the increasing human activity, the air temperature and the precipitation along the Qinghai-Tibet Railway increased gradually in recent years, which endanger the permafrost table, the embankment of the railway. The statistics of the air temperature, the precipitation and the geothermal temperature in recent 50 years in this dissertation come from the four weather station along the railway, that are Wudaoliang Station, Fenghuo Mountains Sta- tion, Tuotuo River Station and Ando Station. This dissertation analyzes the change of climate along the railway and then develops a research on the effect of the changing geothermal temperature on permafrost table and its countermeasures. The experiment result shows that the air temperature of the permafrost region rise steadily in about 50 years, especially in this century, the tendency of rising temperature is more obvious. The precipitation fluctuates but it is also rising rapidly, for the largest precipitation reached 492.6 mm. For 30 years now, the Qinghai-Tibet Plateau has been in the megathermal period, which also affects the permafrost region along the railway. The condition of permafrost is degrading greatly.