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T cell senescence may contribute to immunothrombosis via Th17 immune transition in COVID-19
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作者 Wenxing Li Rui Qian +22 位作者 zhaoming zhou Lei Wen Quan Yin Xiang zhou Xiaowei Li Jie Cheng Xinlu Zhang Xin Zeng Zhuoya Wang Yingying Huang Shengqiang Wang Yixing Liao Youjiang Li Shenbing Shan Meijuan zhou Wu Wei Amir Abdollahi Avery August Nicholas Magazine Gianluca Veggiani Weishan Huang Daogang Guan Cheng zhou 《Science Bulletin》 SCIE EI CAS 2024年第22期3501-3506,共6页
Lymphocyte dysregulation and coagulopathy are closely correlated with the severity and fatal risks of coronavirus disease 2019(COVID-19).Patients with lymphopenia showed a remarkably higher risk of progressive thrombo... Lymphocyte dysregulation and coagulopathy are closely correlated with the severity and fatal risks of coronavirus disease 2019(COVID-19).Patients with lymphopenia showed a remarkably higher risk of progressive thrombosis and abnormal coagulation[1].Up to 80%of severely ill and deceased COVID-19 patients have been found to have diffuse alveolar damage and fibrinous thrombi[2].Autopsy studies confirmed widespread pulmonary embolism and microthrombosis in multiple organs,including but not limited to the lung,kidney,liver,heart,and brain[3]. 展开更多
关键词 thrombosis Th17 organs
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