Lymphocyte dysregulation and coagulopathy are closely correlated with the severity and fatal risks of coronavirus disease 2019(COVID-19).Patients with lymphopenia showed a remarkably higher risk of progressive thrombo...Lymphocyte dysregulation and coagulopathy are closely correlated with the severity and fatal risks of coronavirus disease 2019(COVID-19).Patients with lymphopenia showed a remarkably higher risk of progressive thrombosis and abnormal coagulation[1].Up to 80%of severely ill and deceased COVID-19 patients have been found to have diffuse alveolar damage and fibrinous thrombi[2].Autopsy studies confirmed widespread pulmonary embolism and microthrombosis in multiple organs,including but not limited to the lung,kidney,liver,heart,and brain[3].展开更多
基金supported by the National Natural Science Foundation of China(82273576)。
文摘Lymphocyte dysregulation and coagulopathy are closely correlated with the severity and fatal risks of coronavirus disease 2019(COVID-19).Patients with lymphopenia showed a remarkably higher risk of progressive thrombosis and abnormal coagulation[1].Up to 80%of severely ill and deceased COVID-19 patients have been found to have diffuse alveolar damage and fibrinous thrombi[2].Autopsy studies confirmed widespread pulmonary embolism and microthrombosis in multiple organs,including but not limited to the lung,kidney,liver,heart,and brain[3].