Diabetes is a chronic metabolic disease characterized by high glucose concentration in blood.Conventional management of diabetes requires skin pricking and subcutaneous injection,causing physical pain and physiologica...Diabetes is a chronic metabolic disease characterized by high glucose concentration in blood.Conventional management of diabetes requires skin pricking and subcutaneous injection,causing physical pain and physiological issues to diabetic individuals.Hydrogels possess unique advantages such as lightweight,stretchability,biocompatibility,and biodegradability,offering the opportunities to be integrated as flexible devices for diabetes management.This review highlights the development of hydrogels as flexible materials for diabetes applications in glucose monitoring,insulin delivery,wound care,and cell transplantation in recent years.Challenges and prospects in the development of hydrogel-based flexible devices for personalized management of diabetes are discussed as well.展开更多
基金supported by National Natural Science Foundation of China(52003224,52073230,and 61935017)Natural Science Basic Research Program of Shaanxi Province(2020GXLH-Z-013,2019JQ-157,and 2019KJXX-064)+3 种基金Projects of International Cooperation and Exchanges NSFC(51811530018)Ningbo Natural Science Foundation(202003N4051)Fundamental Research Funds for Central UniversitiesT.J.W.was supported by funding from Yulin Municipal Science and Technology Bureau and the open research fund of Key Laboratory for Organic Electronics and Information Displays.
文摘Diabetes is a chronic metabolic disease characterized by high glucose concentration in blood.Conventional management of diabetes requires skin pricking and subcutaneous injection,causing physical pain and physiological issues to diabetic individuals.Hydrogels possess unique advantages such as lightweight,stretchability,biocompatibility,and biodegradability,offering the opportunities to be integrated as flexible devices for diabetes management.This review highlights the development of hydrogels as flexible materials for diabetes applications in glucose monitoring,insulin delivery,wound care,and cell transplantation in recent years.Challenges and prospects in the development of hydrogel-based flexible devices for personalized management of diabetes are discussed as well.
