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Polyphosphorous acid catalyzed cyclization in the synthesis of cryptolepine derivatives 被引量:2
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作者 Sheng Biao Wan zhe lin liu +2 位作者 Di Chen Qing Ping Dou Tao Jiang 《Chinese Chemical Letters》 SCIE CAS CSCD 2007年第10期1179-1181,共3页
11-Oxo-10,11-dihydroxy-SH-indolo[3,2,b]quinoline7-carboxylic acid was obtained specifically by polyphosphorous acid catalyzed cyclization with optimal reaction conditions. Biological assays showed that it potentially ... 11-Oxo-10,11-dihydroxy-SH-indolo[3,2,b]quinoline7-carboxylic acid was obtained specifically by polyphosphorous acid catalyzed cyclization with optimal reaction conditions. Biological assays showed that it potentially inhibits the proteasomal chymotrypsin-like activity in vitro and suppresses breast cancer cell growth. 展开更多
关键词 CRYPTOLEPINE Trioligomer SYNTHESIS PROTEASOME
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