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Rare primary colonic T cell lymphoma with curative resection by endoscopic submucosal dissection:A case report
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作者 Yu-Hui Sun Shuang-Shuang Lu +3 位作者 Ying Fang zhe xiong Qiu-Yue Sun Jin Huang 《World Journal of Clinical Cases》 SCIE 2024年第22期5229-5235,共7页
BACKGROUND The gastrointestinal tract is a well-known extranodal site of lymphoma.B-cell lymph-oma is the most common type,while T-cell lymphoma is uncommon.Primary gastrointestinal lymphoma mainly occurs in the stoma... BACKGROUND The gastrointestinal tract is a well-known extranodal site of lymphoma.B-cell lymph-oma is the most common type,while T-cell lymphoma is uncommon.Primary gastrointestinal lymphoma mainly occurs in the stomach and small intestine,and the colon is less frequently involved,especially in females.CASE SUMMARY A 45-year-old woman was admitted to our hospital for physical examination.Gastroenteroscopy revealed a visible pedunculated polyp in the transverse colon,for which endoscopic submucosal dissection(ESD)was performed.Pathology suggested highly active proliferation of T lymphocytes with atypical hyperplasia.CONCLUSION A middle-aged female patient was found to have colonic T-cell lymphoma by endoscopy.The lesion was successfully removed by ESD,and the surgical margin was negative.It is essential to raise awareness of colonic T-cell lymphoma and choose the appropriate treatment. 展开更多
关键词 Primary colorectal lymphoma T-cell lymphoma Endoscopic submucosal dissection Pedunculated polyp Case report
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坚果改善慢性应激致抑郁症大鼠行为学表现及其机制研究
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作者 熊哲 范蕾 +2 位作者 段佩 蔡文翔 叶顺杰 《华中师范大学学报(自然科学版)》 CAS CSCD 北大核心 2019年第6期956-961,967,共7页
为探讨坚果(核桃与甜杏仁)在抑郁症中的预防作用和机制.采用慢性温和不可预测应激(CMS)大鼠模型模拟抑郁症,对大鼠进行强迫游泳(FST)、糖水消耗的抑郁症行为学测试,并运用ELISA试剂盒测定大鼠血浆皮质酮(CORT)含量,Western blot法检测... 为探讨坚果(核桃与甜杏仁)在抑郁症中的预防作用和机制.采用慢性温和不可预测应激(CMS)大鼠模型模拟抑郁症,对大鼠进行强迫游泳(FST)、糖水消耗的抑郁症行为学测试,并运用ELISA试剂盒测定大鼠血浆皮质酮(CORT)含量,Western blot法检测大鼠海马部脑源性营养因子(BDNF)、蛋白激酶A(PKA)和蛋白激酶C(PKC)的蛋白表达.实验结果表明,模型组FST、糖水消耗的行为学成绩明显低于正常对照组(P<0.05),预先给予坚果各剂量(60 g·kg^-1、120 g·kg^-1、240 g·kg^-1),可改善抑郁症大鼠的行为学成绩,提示,食用坚果可延缓抑郁症症状.血浆CORT水平测定结果显示,模型组血浆CORT含量显著高于正常对照组(P<0.05),但坚果各剂量组对血浆CORT含量无影响(P>0.05),提示,坚果产生延缓抑郁发生的机制可能与作用CORT途径无关联.对大鼠海马部的BDNF、PKA和PKC蛋白表达测定显示,模型组BDNF、PKA和PKC的蛋白表达均低于正常对照组(P<0.05),而经预先给与坚果的各剂量坚果组,则拮抗了模型组BDNF、PKA和PKC蛋白表达水平的下降(P<0.05).提示,坚果在预防抑郁症作用机制可能与激活PKA、PKC激酶和增强BDNF蛋白水平的信号通路有关.因此,本实验结果初步明确,预先食用坚果可有助于延缓抑郁症的产生.这将为后续食用坚果类食物在预防抑郁症中的研究提供了一定的理论和实验依据. 展开更多
关键词 坚果 慢性应激 抑郁症 大鼠 行为学表现
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黑河流域降水统计——动力降尺度问题研究 被引量:1
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作者 苏海锋 戴新刚 +1 位作者 熊喆 延晓冬 《大气科学》 CSCD 北大核心 2023年第3期642-654,共13页
依据区域气候模式RIEMS2.0输出的3 km高分辨率数据和站点降水记录分析了中国西北黑河流域降水的动力降尺度和统计—动力降尺度问题,检验了多种因子组合下多元线性回归(MLR)和贝叶斯模式平均(BMA)降尺度模型,评估了降尺度降水的均方根误... 依据区域气候模式RIEMS2.0输出的3 km高分辨率数据和站点降水记录分析了中国西北黑河流域降水的动力降尺度和统计—动力降尺度问题,检验了多种因子组合下多元线性回归(MLR)和贝叶斯模式平均(BMA)降尺度模型,评估了降尺度降水的均方根误差、相关系数、方差百分率及“负降水”偏差率等方面的统计特征。结果表明,动力降尺度降水相关系数最高,误差也最大,降水方差达到观测值的1.5~2倍;除相关系数外,统计—动力降尺度模型的几个统计特征均最优,纯统计模型次之。检验表明,仅用700 hPa位势高度场、经向风和比湿等构建的统计降尺度模型估计的站点降水相关系数较低,均方根误差也较大。当在统计降尺度模型中引入模式降水因子后站点降水的估计得到明显改善,其中MLR类模型的降水相关系数和方差百分率均明显高于BMA类模型,均方根误差二者相当,但前者“负降水”出现频次明显大于后者,“负降水”偏差主要出现在降水稀少的冬半年及黑河中、下游干旱或极端干旱区,上游出现频率较低,其中MLR类模型“负降水”出现频次明显高于BMA类模型,后者仅出现在黑河中、下游地区。包含模式降水因子的统计—动力降尺度模型能减少“负降水”出现的频次。此外,降尺度模型估计降水的统计特征随季节变化,其中7种降尺度模型估计的站点降水误差与站点气候降水量成比例,但相对误差与之相反。这些评估结果表明,即使用高分辨率动力降尺度估计干旱区站点降水也存在明显偏差,需要结合统计降尺度模型进一步降低站点降水估计的不确定性。 展开更多
关键词 黑河流域 极端干旱区 站点降水估计 区域气候模式 统计—动力降尺度
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Roles of furfural during the thermal treatment of bio-oil at low temperatures 被引量:2
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作者 zhe xiong Yuanjing Chen +8 位作者 Muhammad Mufti Azis Xun Hu Wei Deng Hengda Han Long Jiang Sheng Su Song Hu Yi Wang Jun Xiang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2020年第11期85-95,共11页
The reactive O-containing species in bio-oil could induce the polymerization of bio-oil during its thermal treatment, which affects the relevant utilization of bio-oil significantly. Furans, as the highly reactive Oco... The reactive O-containing species in bio-oil could induce the polymerization of bio-oil during its thermal treatment, which affects the relevant utilization of bio-oil significantly. Furans, as the highly reactive Ocontaining species in bio-oil, play important roles during the thermal treatment of bio-oil. In this study,furfural was chosen as the representative of the furans in bio-oil to investigate its roles during the thermal treatment of bio-oil. The raw bio-oil with and without the addition of extra furfural(10 wt% of bio-oil) and pure furfural were pyrolyzed in a fixed-bed reactor at 200–500 ℃. The results show that the interactions among furfural and bio-oil components can take place prior to the evaporation of furfural(<140 ℃) to form the intermediates, then these intermediates could be further polymerized to form large molecular compounds, and coke can be formed via the interactions at temperatures ≥ 300 ℃. At temperatures ≤ 300 ℃, furfural mainly interacts with anhydrosugars. As the temperature further increases, the aromatics are involved in the interactions to form coke. The increased percentage of the coke formed via the interactions is in a linear relation with the conversion of furfural during the pyrolysis at 300–500 ℃(no coke formed at 200 ℃). Meanwhile, more non-aromatic light components(≤ C6) and less aromatics in the tars could be formed due to the interactions. 展开更多
关键词 BIO-OIL FURFURAL AROMATIC COKE POLYMERIZATION Interaction
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Manipulating Zr/Ti ratio based on phase diagram for large electrocaloric effects with multiple target operation temperatures in PLZT ceramics
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作者 Junjie Li Ruowei Yin +5 位作者 zhe xiong Yizheng Bao Xing Zhang Wenjuan Wu Lezhong Li Yang Bai 《Journal of Advanced Ceramics》 SCIE EI CAS CSCD 2024年第9期1422-1431,共10页
Ferroelectric phase transition has been identified as a promising avenue for designing high-performanceelectrocaloric materials for zero-emission and solid-state refrigeration. However, extensive research has been lim... Ferroelectric phase transition has been identified as a promising avenue for designing high-performanceelectrocaloric materials for zero-emission and solid-state refrigeration. However, extensive research has been limited todeveloping ferroelectric materials with large electrocaloric effects near room temperature, preventing them from meetingdiverse refrigeration requirements. In this study, by leveraging the room-temperature phase diagram of the (PbLa)(ZrTi)O_(3)solution, we prepared a series of Pb_(0.775)La_(0.15)Zr_(x)Ti_(1−x)O_(3) bulk ceramics spanning the ferroelectric and relaxor ferroelectricphase regions. This enabled the attainment of various phase transition features and temperatures. Finally, largeelectrocaloric effects, coupled with adjustable operation temperatures ranging from 150 to −45℃, are successfullyachieved through manipulation of the Zr/Ti ratio. This comprehensive range of operation temperatures effectively addressesdiverse refrigeration application requirements, ranging from industrial equipment to freezer cabinets. This work not onlyunderscores the expansion of the electrocaloric refrigeration application domain but also proposes a material designstrategy tailored to meet these evolving demands. 展开更多
关键词 electrocaloric effect phase transition phase diagram ferroelectric ceramics
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The Aerosol Radiative Effect on a Severe Haze Episode in the Yangtze River Delta 被引量:4
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作者 Kai SUN Hongnian LIU +2 位作者 Xueyuan WANG zhen PENG zhe xiong 《Journal of Meteorological Research》 SCIE CSCD 2017年第5期865-873,共9页
Due to increased aerosol emissions and unfavorable weather conditions, severe haze events have occurred fre- quently in China in the last 10 years. In addition, the interaction between the boundary layer and the aeros... Due to increased aerosol emissions and unfavorable weather conditions, severe haze events have occurred fre- quently in China in the last 10 years. In addition, the interaction between the boundary layer and the aerosol radiative effect may be another important factor in haze formation. To better understand the effect of this interaction, the aero- sol radiative effect on a severe haze episode that took place in December 2013 was investigated by using two WRF- Chem model simulations with different aerosol configurations. The results showed that the maximal reduction of re- gional average surface shortwave radiation, latent heat, and sensible heat during this event were 88, 12, and 37 W m2, respectively. The planetary boundary layer height, daytime temperature, and wind speed dropped by 276 m, I^C, and 0.33 m s-l, respectively. The ventilation coefficient dropped by 8%-24% for in the central and northwestern Yangtze River Delta (YRD). The upper level of the atmosphere was warmed and the lower level was cooled, which stabilized the stratification. In a word, the dispersion ability of the atmosphere was weakened due to the aerosol radi- ative feedback. Additional results showed that the PM2.5 concentration in the central and northwestern YRD in- creased by 6-18 p.g m3, which is less than 15% of the average PM2.5 concentration during the severely polluted peri- od in this area. The vertical profile showed that the PM2.5 and PM10 concentrations increased below 950 hPa, with a maximum increase of 7 and 8 gg m-3, respectively. Concentrations reduced between 950 and 800 hPa, however, with a maximum reduction of 3.5 and 4.5 p.g rn-3, respectively. Generally, the aerosol radiative effect aggravated the level of pollution, but the effect was limited, and this haze event was mainly caused by the stagnant meteorological condi- tions. The interaction between the boundary layer and the aerosol radiative effect may have been less important than the large-scale static weather conditions for the formation of this haze episode. 展开更多
关键词 HAZE aerosol radiative effect Yangtze River Delta ventilation coefficient PM2.5 WRF-Chem
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Shape optimization of aluminium alloy spherical reticulated shells considering nonlinearities 被引量:1
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作者 Wei LIU Lishu XU +3 位作者 Shaojun ZHU Lijuan LI Feng LIU zhe xiong 《Frontiers of Structural and Civil Engineering》 SCIE EI CSCD 2022年第12期1565-1580,共16页
This study proposes a shape optimization method for K6 aluminum alloy spherical reticulated shells with gusset joints,considering geometric,material,and joint stiffness nonlinearities.The optimization procedure adopts... This study proposes a shape optimization method for K6 aluminum alloy spherical reticulated shells with gusset joints,considering geometric,material,and joint stiffness nonlinearities.The optimization procedure adopts a genetic algorithm in which the elastoplastic non-linear buckling load is selected as the objective function to be maximized.By confinement of the adjustment range of the controlling points,optimization results have enabled a path toward achieving a larger elastoplastic non-linear buckling load without changing the macroscopic shape of the structure.A numerical example is provided to demonstrate the effectiveness of the proposed method.In addition,the variation in structural performance during optimization is illustrated.Through parametric analysis,practical design tables containing the parameters of the optimized shape are obtained for aluminum alloy spherical shells with common geometric parameters.To explore the effect of material nonlinearity,the optimal shapes obtained based on considering and not considering material non-linear objective functions,the elastoplastic and elastic non-linear buckling loads,are compared. 展开更多
关键词 shape optimization aluminum alloy spherical reticulated shell non-linear buckling material nonlinearity genetic algorithm
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