To the Editor:Colorectal cancer(CRC)is a major cause of cancer-related death worldwide,and several pathogens with carcinogenic potential,such as Schistosoma,have been associated with an increased risk of CRC.As a freq...To the Editor:Colorectal cancer(CRC)is a major cause of cancer-related death worldwide,and several pathogens with carcinogenic potential,such as Schistosoma,have been associated with an increased risk of CRC.As a frequently mutated gene in CRC patients,kirsten rat sarcoma viral oncogene homolog(KRAS)helps to determine the selection of CRC therapies.Therefore,we aimed to elucidate the association among Schistosoma infection,KRAS mutation status,and the prognosis of CRC in this study.展开更多
基金supported by grants from the National Key Research and Development Program of China(Nos.2022YFF1203300 and 2018YFC1313300)the National Natural Science Foundation of China(Nos.81702392 and 81472707)+1 种基金the Chinese South Western Oncology Group(No.CSWOG-CCET005)the Beijing Bethune Public Welfare Foundation(No.BJ-GYQZHX2021006)
文摘To the Editor:Colorectal cancer(CRC)is a major cause of cancer-related death worldwide,and several pathogens with carcinogenic potential,such as Schistosoma,have been associated with an increased risk of CRC.As a frequently mutated gene in CRC patients,kirsten rat sarcoma viral oncogene homolog(KRAS)helps to determine the selection of CRC therapies.Therefore,we aimed to elucidate the association among Schistosoma infection,KRAS mutation status,and the prognosis of CRC in this study.
