Objective:To observe the effect of tetradecylene naphthalene soft capsule combined with Yishen Gubenyutong Decoction on bone metabolism and bone turnover in patients with osteoporosis and its clinical efficacy.Methods...Objective:To observe the effect of tetradecylene naphthalene soft capsule combined with Yishen Gubenyutong Decoction on bone metabolism and bone turnover in patients with osteoporosis and its clinical efficacy.Methods:A total of 100 patients with primary osteoporosis(all were treated by our hospital from February 2017 to June 2018)were divided into two groups.The control group(50 cases)was given to menatetrenone capsules.Treatment,observation group(50 cases)combined with Yishen Gubenqiaotongtong on the basis of the treatment of the control group,6 months for a course of treatment.The bone metabolic markers,bone mineral density changes and clinical efficacy were measured before and after treatment.Results:The total effective rate of the observation group was higher than that of the control group.After treatment,the observation group showed serum calcium(Ca),serum alkaline phosphatase(ALP)and typeⅠcollagen.The level of cross-linked C-terminal peptide(CTX-1)was lower than that of the control group.After treatment,the osteocalcin(OC)in the observation group was higher than that in the control group,and the bone mineral density(BMD)of lumbar vertebrae L2-4,femoral neck and femur trochanter in the observation group were higher than those in the control group.Conclusion:Menatetrenone soft capsule combined with Yishen Gubenyutong Decoction has good clinical effect on osteoporosis patients and it is worth further promotion in clinic.展开更多
Oilseed rape （Brassica napus L.） is one of the most important oil crops worldwide and provides about 50 percent of the vegetable oil supply in China （Yin et al., 2009）. The development of rapeseed varieties with h...Oilseed rape （Brassica napus L.） is one of the most important oil crops worldwide and provides about 50 percent of the vegetable oil supply in China （Yin et al., 2009）. The development of rapeseed varieties with higher yield is an effective measure to optimize balance between the supply and demand of edible vegetable oil. In oilseed rape, the number of silique per plant （SP） contributes most to the yield performance （Diepenbrock, 2000）. However, compared with the other two yield-component traits, seeds per silique （SS） and seed weight （SW）, SP is more sensitive to environmental changes （Li et al., 2007; Shi et al., 2009）. Therefore, it is difficult to perform the genetic improvement on SP trait directly in oilseed rape.展开更多
基金Scientific Research Project of Guangdong Traditional Chinese Medicine Bureau(20191292).
文摘Objective:To observe the effect of tetradecylene naphthalene soft capsule combined with Yishen Gubenyutong Decoction on bone metabolism and bone turnover in patients with osteoporosis and its clinical efficacy.Methods:A total of 100 patients with primary osteoporosis(all were treated by our hospital from February 2017 to June 2018)were divided into two groups.The control group(50 cases)was given to menatetrenone capsules.Treatment,observation group(50 cases)combined with Yishen Gubenqiaotongtong on the basis of the treatment of the control group,6 months for a course of treatment.The bone metabolic markers,bone mineral density changes and clinical efficacy were measured before and after treatment.Results:The total effective rate of the observation group was higher than that of the control group.After treatment,the observation group showed serum calcium(Ca),serum alkaline phosphatase(ALP)and typeⅠcollagen.The level of cross-linked C-terminal peptide(CTX-1)was lower than that of the control group.After treatment,the osteocalcin(OC)in the observation group was higher than that in the control group,and the bone mineral density(BMD)of lumbar vertebrae L2-4,femoral neck and femur trochanter in the observation group were higher than those in the control group.Conclusion:Menatetrenone soft capsule combined with Yishen Gubenyutong Decoction has good clinical effect on osteoporosis patients and it is worth further promotion in clinic.
基金supported by the Hi-Tech Research and Development program of China (Grant No. 2011AA10A104)the National Natural Science Foundation of China (Grant Nos. 31171589 and 31201244)+1 种基金the National Basic Research Program (Grant No. 2011CB109302)the Special Fund for Agroscientific Research in the Public Interest (Grant No. 2101203032)
文摘Oilseed rape （Brassica napus L.） is one of the most important oil crops worldwide and provides about 50 percent of the vegetable oil supply in China （Yin et al., 2009）. The development of rapeseed varieties with higher yield is an effective measure to optimize balance between the supply and demand of edible vegetable oil. In oilseed rape, the number of silique per plant （SP） contributes most to the yield performance （Diepenbrock, 2000）. However, compared with the other two yield-component traits, seeds per silique （SS） and seed weight （SW）, SP is more sensitive to environmental changes （Li et al., 2007; Shi et al., 2009）. Therefore, it is difficult to perform the genetic improvement on SP trait directly in oilseed rape.
