Type 1 diabetes mellitus(T1DM),an autoimmune disorder,is marked by T cell-mediated destruction of theβcells of the pancreas,which leads to an almost complete loss of the ability to synthesize insulin.[1]This insulin ...Type 1 diabetes mellitus(T1DM),an autoimmune disorder,is marked by T cell-mediated destruction of theβcells of the pancreas,which leads to an almost complete loss of the ability to synthesize insulin.[1]This insulin deficiency results in loss of the ability to regulate blood sugar,therefore,exogenous insulin administration is necessary for patients to control blood sugar and to reduce the incidence of related chronic diabetic complications.[2]In addition,a positive correlation between diabetes mellitus and hypertension has been detected.[3]展开更多
基金supported by grants from the National Natural Science Foundation of China(No.81803418)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(No.18KJD350001)Project for Youth Scholar of Jiangsu Collaborative Innovation Center of Regional Modern Agriculture&Environmental Projection(No.HSXT2-314)。
文摘Type 1 diabetes mellitus(T1DM),an autoimmune disorder,is marked by T cell-mediated destruction of theβcells of the pancreas,which leads to an almost complete loss of the ability to synthesize insulin.[1]This insulin deficiency results in loss of the ability to regulate blood sugar,therefore,exogenous insulin administration is necessary for patients to control blood sugar and to reduce the incidence of related chronic diabetic complications.[2]In addition,a positive correlation between diabetes mellitus and hypertension has been detected.[3]
