The nitrile functionality is a key building block in synthetic chemistry, and has wide applications in pharmaceuticals. However, traditional methodologies for the synthesis of nitriles are limited to harsh reaction co...The nitrile functionality is a key building block in synthetic chemistry, and has wide applications in pharmaceuticals. However, traditional methodologies for the synthesis of nitriles are limited to harsh reaction conditions. Herein, we report a new and efficient access to aryl nitriles by an electrochemical synthesis. Compared with the conventional synthetic methods, this electrochemical synthesis is more environmentally friendly and easier to handle.展开更多
A highly efficient conformation from facile benzoylhydrazines was developed under electrochemical condition. A variety of oxadiazoles were obtained with good yields by virtue of this new method.
基金financially supported by the National Natural Science Foundation of China (Nos. 2127222, 91213303, 21172205, J1030412)
文摘The nitrile functionality is a key building block in synthetic chemistry, and has wide applications in pharmaceuticals. However, traditional methodologies for the synthesis of nitriles are limited to harsh reaction conditions. Herein, we report a new and efficient access to aryl nitriles by an electrochemical synthesis. Compared with the conventional synthetic methods, this electrochemical synthesis is more environmentally friendly and easier to handle.
基金the National Natural Science Foundation of China(Nos.91213303,21272222,20932002,21172205)for the financial support
文摘A highly efficient conformation from facile benzoylhydrazines was developed under electrochemical condition. A variety of oxadiazoles were obtained with good yields by virtue of this new method.
