Background：Asthma is a common chronic respiratory disease and is related to air pollution exposure.However,only a few studies have concentrated on the association between air pollution and adult asthma.Moreover,the r...Background：Asthma is a common chronic respiratory disease and is related to air pollution exposure.However,only a few studies have concentrated on the association between air pollution and adult asthma.Moreover,the results of these studies are controversial.Therefore,the present study aimed to analyze the influence of various pollutants on hospitalization due to asthma in adults.Methods：A total of 1019 unrelated hospitalized adult asthma patients from Northeast China were recruited from 2014 to 2016.Daily average concentrations of air pollutants （particulate matter ＜2.5 μm [PM2.5],particulate matter ＜ 10 μm [PM 10],sulfur dioxide [SO2],nitrogen dioxide [NO2],and carbon monoxide [CO]） were obtained from the China National Environmental Monitoring Centre website from 2014 to 2016.Cox logistic regression analysis was used to analyze the relationship between air pollutants and hospital admissions in adult asthma.Results：The maximum odds ratio （OR） value for most air pollutants occurred on lag day 1.Lag day 1 was chosen as the exposure period,and 8 days before onset was chosen as the control period.Three pollutants （PM2.5,CO,and SO2） were entered into the regression equation,and the corresponding OR （95％ confidence interval） was 0.995 （0.991-0.999）,3.107 （1.607-6.010）,and 0.979 （0.968-0.990）,respectively.Conclusions：A positive association between hospital admissions and the daily average concentration of CO was observed.CO is likely to be a risk factor for hospital admissions in adults with asthma.展开更多
Mucoepidermoid carcinomas （MECs） had always been recognized as salivary gland tumors mainly steming from parotid and submandibular salivary glands. Eater, studies showed that MECs can occur in bronchus, esophagus, l...Mucoepidermoid carcinomas （MECs） had always been recognized as salivary gland tumors mainly steming from parotid and submandibular salivary glands. Eater, studies showed that MECs can occur in bronchus, esophagus, lacrimal glands, pancreas, thymus, and thyroid gland. MECs in bronchus are usually centrally located and are proposed to originate from submucosal minor salivary-type glands in large airways.展开更多
Male germ cell tumors （GCTs） are predominantly derived from testis, while about 2-5% of which arise at extragonadal sites. Extragonadal GCTs （EGCTs） have similar histological components as gonadal GCTs and often o...Male germ cell tumors （GCTs） are predominantly derived from testis, while about 2-5% of which arise at extragonadal sites. Extragonadal GCTs （EGCTs） have similar histological components as gonadal GCTs and often occur in the midline of the body, making diagnosis difficult.展开更多
A 48-year-old woman had a symptom of chest pain a month ago, without obvious inducement, coughing, sputum, hemoptysis, or chest tightness. The pain in the chest was irregular. The patient was admitted to the First Hos...A 48-year-old woman had a symptom of chest pain a month ago, without obvious inducement, coughing, sputum, hemoptysis, or chest tightness. The pain in the chest was irregular. The patient was admitted to the First Hospital of lilin University for further treatment. The patient denied the history of hypertension, coronary heart disease, diabetes mellitus, and other diseases. She also denied family history of hereditary disease. However, she has had a smoking history for 20 years, about 10 cigarettes per day, no quit. Physical examination and blood tests did not show apparent abnormality. All tumor markers were negative. The computed tomography （CT） showed a high-density mass of right upper lobe of the lung, which was about 17 mm × 15 mm [Figure 1 a]. The boundary was smooth, and the density was uniform. The image of a narrow arc of fluid was seen in the right thoracic cavity and there was no significant lymph node （LN） metastasis in the mediastinum [Figure lb]. The patient underwent exploration under thoracoscope, and the intraoperative rapid pathology showed suspicious adenocarcinoma, the patient received the resection of the upper lobe of the right lung. However, the final pathology revealed the pulmonary sclerosing hemangioma （PSH）. Microscopic findings of the postoperative specimen showed a mixture of papillary and sclerotic patterns with two cell types as follows： cuboidal surface and stromal round cells. The cuboidal surface cells resembling pneumocytes and round stromal cells with well-defined borders were centrally located round to oval vesicular nuclei and rare nucleoli. The round stromal cells mostly had slightly eosinophilic cytoplasm with some showing a more vacuolated or foamy appearance. In other areas, there were large blood-filled spaces lined by flattened cells. Solid sheets of round cells with scattered cuboidal surface cells forming small tubules were also noted [Figure 1c].展开更多
文摘Background：Asthma is a common chronic respiratory disease and is related to air pollution exposure.However,only a few studies have concentrated on the association between air pollution and adult asthma.Moreover,the results of these studies are controversial.Therefore,the present study aimed to analyze the influence of various pollutants on hospitalization due to asthma in adults.Methods：A total of 1019 unrelated hospitalized adult asthma patients from Northeast China were recruited from 2014 to 2016.Daily average concentrations of air pollutants （particulate matter ＜2.5 μm [PM2.5],particulate matter ＜ 10 μm [PM 10],sulfur dioxide [SO2],nitrogen dioxide [NO2],and carbon monoxide [CO]） were obtained from the China National Environmental Monitoring Centre website from 2014 to 2016.Cox logistic regression analysis was used to analyze the relationship between air pollutants and hospital admissions in adult asthma.Results：The maximum odds ratio （OR） value for most air pollutants occurred on lag day 1.Lag day 1 was chosen as the exposure period,and 8 days before onset was chosen as the control period.Three pollutants （PM2.5,CO,and SO2） were entered into the regression equation,and the corresponding OR （95％ confidence interval） was 0.995 （0.991-0.999）,3.107 （1.607-6.010）,and 0.979 （0.968-0.990）,respectively.Conclusions：A positive association between hospital admissions and the daily average concentration of CO was observed.CO is likely to be a risk factor for hospital admissions in adults with asthma.
文摘Mucoepidermoid carcinomas （MECs） had always been recognized as salivary gland tumors mainly steming from parotid and submandibular salivary glands. Eater, studies showed that MECs can occur in bronchus, esophagus, lacrimal glands, pancreas, thymus, and thyroid gland. MECs in bronchus are usually centrally located and are proposed to originate from submucosal minor salivary-type glands in large airways.
文摘Male germ cell tumors （GCTs） are predominantly derived from testis, while about 2-5% of which arise at extragonadal sites. Extragonadal GCTs （EGCTs） have similar histological components as gonadal GCTs and often occur in the midline of the body, making diagnosis difficult.
基金This study was supported by a grant from the Natural Science Foundation of Jilin Province （No. 20180101099JC）.
文摘A 48-year-old woman had a symptom of chest pain a month ago, without obvious inducement, coughing, sputum, hemoptysis, or chest tightness. The pain in the chest was irregular. The patient was admitted to the First Hospital of lilin University for further treatment. The patient denied the history of hypertension, coronary heart disease, diabetes mellitus, and other diseases. She also denied family history of hereditary disease. However, she has had a smoking history for 20 years, about 10 cigarettes per day, no quit. Physical examination and blood tests did not show apparent abnormality. All tumor markers were negative. The computed tomography （CT） showed a high-density mass of right upper lobe of the lung, which was about 17 mm × 15 mm [Figure 1 a]. The boundary was smooth, and the density was uniform. The image of a narrow arc of fluid was seen in the right thoracic cavity and there was no significant lymph node （LN） metastasis in the mediastinum [Figure lb]. The patient underwent exploration under thoracoscope, and the intraoperative rapid pathology showed suspicious adenocarcinoma, the patient received the resection of the upper lobe of the right lung. However, the final pathology revealed the pulmonary sclerosing hemangioma （PSH）. Microscopic findings of the postoperative specimen showed a mixture of papillary and sclerotic patterns with two cell types as follows： cuboidal surface and stromal round cells. The cuboidal surface cells resembling pneumocytes and round stromal cells with well-defined borders were centrally located round to oval vesicular nuclei and rare nucleoli. The round stromal cells mostly had slightly eosinophilic cytoplasm with some showing a more vacuolated or foamy appearance. In other areas, there were large blood-filled spaces lined by flattened cells. Solid sheets of round cells with scattered cuboidal surface cells forming small tubules were also noted [Figure 1c].
