Effect of orthodontic force on inflammatory periodontal tissue remodeling and expression of IL-6 and IL-8 in rats

Objective:To investigate effect of orthodontic force on inflammatory periodontal tissue remodeling and expression of IL-6 and IL-8 in rats.Methods:Eighty SD rats were randomly divided into 4 groups,blank control group(group A)with 5 rats,treatment normal group(group B)with 25 rats,inflammation control group(group(group C)with 25 rats,inflammation treatment group(group D)with 25 rats.Immunohistochemistry and histomorphometric analysis was performed to measure the expression of IL-6,IL-8 and the firet molar to the recent movement in the distance.Results:The expression of IL-8 reached a maximum on day 5 and declined thereafter in group B;the expression of IL-6 reached a maximum on day 5 in group B.The expression of IL-6 and IL-8 was gradually weakened with time in group C.The expression of IL-6 and IL-8 were high,and reached a maximum on day 5 and declined thereafter in group D.AD of positive cells in group D were higher than group B at each time point(P<0.05).The time which 0.49 N orthodontic force was loaded was longer,orthodontic tooth movement distance was greater.Movement distance in group D were longer than group B(P<0.05).Conclusions:Orthodontic force as well as inflammatory stimulus can evoke the expression of IL-6 and IL-8.Under the combined effects of inflammation and orthodontic force,the expression of IL-6,IL-8will increase.

荧光胆道显影在腹腔镜复杂胆囊切除术中的应用

目的探讨荧光胆道显影技术在腹腔镜复杂胆囊切除术中的应用。方法选取2018年9月—2019年8月于徐州市中心医院收治的复杂胆囊切除患者100例,按照不同手术方法分为试验组和对照组,每组50例。对照组使用常规腹腔镜胆囊切除术;试验组在荧光胆道显影下行腹腔镜胆囊切除术。观察两组患者术中相关情况,术后恢复情况及手术并发症。结果试验组手术时间短于对照组,术中出血量少于对照组(P<0.05)。试验组肛门排气时间、术后住院时间较对照组短(P<0.05)。试验组并发症总发生率较对照组低(P<0.05)。结论荧光胆道显影能够改善复杂腹腔镜复杂胆囊切除术中情况,降低手术相关并发症,有效促进患者术后康复。