Primary mucinous carcinoma of the thyroid gland which is more difficult to diagnose than common thyroid cancer is an extremely rare disease.It is a malignant tumor that can secrete mucus.A 45-year-old Chinese man came...Primary mucinous carcinoma of the thyroid gland which is more difficult to diagnose than common thyroid cancer is an extremely rare disease.It is a malignant tumor that can secrete mucus.A 45-year-old Chinese man came to seek medical care because he found a lump in his right side.Tomography showed that there was a space-occupying lesion on the right thyroid gland which compressed the tracheal.After the operation of total thyroidectomy and lymph node dissection in the right central area,the pathological examination showed that tumor cells existed,showing a small nest-like and cribriform distribution characteristics.There were broad fibrous tissues,a large amount of mucus around the tumur cell that had no obvious amyloid deposition.The tumor cells were positive for thyroid transcription factor-1 and paired box gene-8,while they were focally positive for thyroglobulin.Considering the histological features and immunohistochemical profile and ruling out mucinous cancers originating from other organs.The patient was diagnosed with primary mucinous carcinoma of the thyroid gland.This patient is still alive at present.Prognosis of primary mucinous carcinoma of the thyroid gland is usually poor.The best way to improve the prognosis of these patients maybe to do surgery of complete tumor+lymph node resection as soon as possible.展开更多
文摘Primary mucinous carcinoma of the thyroid gland which is more difficult to diagnose than common thyroid cancer is an extremely rare disease.It is a malignant tumor that can secrete mucus.A 45-year-old Chinese man came to seek medical care because he found a lump in his right side.Tomography showed that there was a space-occupying lesion on the right thyroid gland which compressed the tracheal.After the operation of total thyroidectomy and lymph node dissection in the right central area,the pathological examination showed that tumor cells existed,showing a small nest-like and cribriform distribution characteristics.There were broad fibrous tissues,a large amount of mucus around the tumur cell that had no obvious amyloid deposition.The tumor cells were positive for thyroid transcription factor-1 and paired box gene-8,while they were focally positive for thyroglobulin.Considering the histological features and immunohistochemical profile and ruling out mucinous cancers originating from other organs.The patient was diagnosed with primary mucinous carcinoma of the thyroid gland.This patient is still alive at present.Prognosis of primary mucinous carcinoma of the thyroid gland is usually poor.The best way to improve the prognosis of these patients maybe to do surgery of complete tumor+lymph node resection as soon as possible.
