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羊膜移植联合冷冻术与板层角膜移植术治疗蚕食性角膜溃疡的近中期疗效比较 被引量:2
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作者 彭正武 周亮 +3 位作者 邝国平 周小平 李植源 陈书扬 《中国现代医学杂志》 CAS 北大核心 2021年第21期26-31,共6页
目的分析羊膜移植联合冷冻术与板层角膜移植术治疗蚕食性角膜溃疡的近中期效果。方法选取2017年12月—2019年12月郴州市第一人民医院收治的88例蚕食性角膜溃疡患者为研究对象,根据随机数字表法分为A组和B组,每组44例。A组采用羊膜移植... 目的分析羊膜移植联合冷冻术与板层角膜移植术治疗蚕食性角膜溃疡的近中期效果。方法选取2017年12月—2019年12月郴州市第一人民医院收治的88例蚕食性角膜溃疡患者为研究对象,根据随机数字表法分为A组和B组,每组44例。A组采用羊膜移植联合冷冻术,B组采用板层角膜移植术。比较两组患者的临床疗效、术后视力、术后恢复情况、疼痛感、并发症、近中期预后。结果两组治疗总有效率比较,差异有统计学意义(P<0.05),B组治疗总有效率比A组高。A组与B组术后1个月、术后6个月、术后12个月视力比较,采用重复测量设计的方差分析,结果:①不同时间点的视力有差异(P<0.05);②A组与B组视力有差异(P<0.05),A组与B组术后视力相比术前视力好,相对恢复效果好;③A组与B组视力变化趋势有差异(P<0.05)。A组角膜上皮愈合时间为(13.26±2.47)d,B组角膜上皮愈合时间为(10.05±1.45)d,B组角膜上皮愈合时间比A组短(P<0.05)。A组羊膜溶解脱落时间为(8.78±1.03)d。两组角膜/角膜植片透明度分级、溃疡愈合率比较,差异有统计学意义(P<0.05),B组角膜植片透明度分级轻于A组,溃疡愈合率高于A组。两组可见角膜新生血管率比较,差异无统计学意义(P>0.05)。A组与B组术后3 d、术后1个月、术后6个月VAS评分比较,采用重复测量设计的方差分析,结果:①不同时间点的VAS评分有差异(P<0.05);②A组与B组VAS评分有差异(P<0.05),A组与B组视力相比术前VAS评分比较低,缓解疼痛效果较好;③A组与B组视力变化趋势有差异(P<0.05)。两组治疗并发症发生率、术后1年及3年原病复发率比较,差异有统计学意义(P<0.05),B组并发症发生率比A组低,术后1年及3年原病复发率比A组高。结论板层角膜移植术治疗蚕食性角膜溃疡更利于提高疗效、促进术后溃疡愈合、提高视力、缓解患者疼痛、降低并发症发生率,但羊膜移植联合冷冻术近中期复发率更低。 展开更多
关键词 蚕食性角膜溃疡 羊膜移植联合冷冻术 板层角膜移植术 视力 复发率
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Effects of TMCP Schedule on Precipitation,Microstructure and Properties of Ti-microalloyed High Strength Steel 被引量:14
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作者 Xiang-dong HUO Lie-jun LI +1 位作者 zheng-wu peng Song-jun CHEN 《Journal of Iron and Steel Research International》 SCIE EI CAS CSCD 2016年第6期593-601,共9页
Using the similar compositions of the Ti-microalloyed high-strength steels produced by the thin-slab casting process of compact strip production(CSP),four thermo-mechanical control processes(TMCP)after the simulat... Using the similar compositions of the Ti-microalloyed high-strength steels produced by the thin-slab casting process of compact strip production(CSP),four thermo-mechanical control processes(TMCP)after the simulated thickslab casting,i.e.the two hot rolling routes and the two cooling processes,were designed,aiming at achieving the same mechanical properties as the thin strip products.The final microstructures after the four TMCP processes were examined by optical microscope(OM),scanning electron microscope(SEM)and transmission electron microscope(TEM).The tensile properties and Charpy impact energy were measured correspondingly.Strain-induced TiC precipitation was found in the two-stage rolling route with the finish rolling temperature at low levels,leading to grain refinement due to the pinning effect during austenite recrystallization.Precipitation hardening in ferrite was observed when a period of isothermal holding was applied after hot rolling.It could be concluded that both finish rolling temperature and the subsequent isothermal holding temperature were crucial for the achieved strength level due to the combined effect of grain refinement and precipitation hardening.At the same time,it was found that the isothermal holding led to poor impact toughness because of remarkable precipitation hardening.Therefore,it was suggested that the precipitation kinetics of titanium carbides in both austenite and ferrite should be investigated in future. 展开更多
关键词 TMCP refinement hardening holding rolling titanium isothermal Precipitation austenite ferrite
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