BACKGROUND Eosinophilic granulomatosis with polyangiitis(EGPA),formerly known as Churg-Strauss syndrome,is a rare form of anti-neutrophil cytoplasmic antibodyassociated vasculitis characterized by asthma,vasculitis,an...BACKGROUND Eosinophilic granulomatosis with polyangiitis(EGPA),formerly known as Churg-Strauss syndrome,is a rare form of anti-neutrophil cytoplasmic antibodyassociated vasculitis characterized by asthma,vasculitis,and eosinophilia.CASE SUMMARY We report an atypical case of EGPA in a 20-year-old female patient.Unlike previously reported cases of EGPA,this patient’s initial symptom was asthma associated with a respiratory infection.This was followed by Loeffler endocarditis and cardiac insufficiency.She received treatment with methylprednisolone sodium succinate,low molecular weight heparin,recombinant human brain natriuretic peptide,furosemide,cefoperazone sodium/sulbactam sodium,and acyclovir.Despite prophylactic anticoagulation,she developed a large right ventricular thrombus.EGPA diagnosis was confirmed based on ancillary test results and specialty consultations.Subsequent treatment included mycophenolate mofetil.Her overall condition improved significantly after treatment,as evidenced by decreased peripheral blood eosinophils and cardiac markers.She was discharged after 17 d.Her most recent follow-up showed normal peripheral blood eosinophil levels,restored cardiac function,and a reduced cardiac mural thrombus size.CONCLUSION This case illustrates the swift progression of EGPA and underscores the significance of early detection and immediate intervention to ensure a favorable prognosis.展开更多
An environment-friendly cerium-based sealing treatment was developed to improve the surface integrity and corrosion resistance of Mg–Al hydrotalcite film on AZ91D magnesium alloy. The cerium dioxide was generated thr...An environment-friendly cerium-based sealing treatment was developed to improve the surface integrity and corrosion resistance of Mg–Al hydrotalcite film on AZ91D magnesium alloy. The cerium dioxide was generated through three stages namely nucleation, growth and dissolution, modifying the surface of AZ91D Mg alloy, and the hydrotalcite film became integral after being treated for 30 min. The results of polarization curves showed that the anti-corrosive performance of the hydrotalcite film was enhanced by the sealing treatment. Moreover, the immersion tests and electrochemical impedance spectrum measurements also demonstrated that the sealed hydrotalcite film provided a longer-term protection of magnesium alloy from corrosion as compared to the unsealed one.展开更多
The biaxial tensile tests were carried out to investigate the deformation behavior and yield loci of dual-phase （DP） steel sheets under biaxial tensile conditions. The true stress-true strain curves of DP steel shee...The biaxial tensile tests were carried out to investigate the deformation behavior and yield loci of dual-phase （DP） steel sheets under biaxial tensile conditions. The true stress-true strain curves of DP steel sheets for different loading ratios were obtained, and the experimental yield loci were determined based on the equivalent plastic work principle. The experimental yield loci were compared to the theoretical yield loci based on Hi1148, Hi1190, Hi1193, Hosford, Barlat89, Yld2000-2d and Gotoh yield criteria. It is found that Yld2000-2d yield criterion can describe the general trends of experimental yield loci of DP steel sheets with comparably higher accuracy. Hosford criterion has the maximum error for DP590, whereas Hi1148 and Barlat89 have the maximum errors for DP780 and DP980.展开更多
基金Supported by the 2020 National Natural Science Foundation Cultivation Project of Guizhou Medical University Affiliated Hospital,No.gyfynsfc[2020]-14.
文摘BACKGROUND Eosinophilic granulomatosis with polyangiitis(EGPA),formerly known as Churg-Strauss syndrome,is a rare form of anti-neutrophil cytoplasmic antibodyassociated vasculitis characterized by asthma,vasculitis,and eosinophilia.CASE SUMMARY We report an atypical case of EGPA in a 20-year-old female patient.Unlike previously reported cases of EGPA,this patient’s initial symptom was asthma associated with a respiratory infection.This was followed by Loeffler endocarditis and cardiac insufficiency.She received treatment with methylprednisolone sodium succinate,low molecular weight heparin,recombinant human brain natriuretic peptide,furosemide,cefoperazone sodium/sulbactam sodium,and acyclovir.Despite prophylactic anticoagulation,she developed a large right ventricular thrombus.EGPA diagnosis was confirmed based on ancillary test results and specialty consultations.Subsequent treatment included mycophenolate mofetil.Her overall condition improved significantly after treatment,as evidenced by decreased peripheral blood eosinophils and cardiac markers.She was discharged after 17 d.Her most recent follow-up showed normal peripheral blood eosinophil levels,restored cardiac function,and a reduced cardiac mural thrombus size.CONCLUSION This case illustrates the swift progression of EGPA and underscores the significance of early detection and immediate intervention to ensure a favorable prognosis.
基金supported by the Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology (No. ASMA201407)the Innovative Foundation Project for Students of Jiangsu Province (No. 201511276012Z)the Innovative Foundation Project for Students of Nanjing Institute of Technology (No. TB201617004)
文摘An environment-friendly cerium-based sealing treatment was developed to improve the surface integrity and corrosion resistance of Mg–Al hydrotalcite film on AZ91D magnesium alloy. The cerium dioxide was generated through three stages namely nucleation, growth and dissolution, modifying the surface of AZ91D Mg alloy, and the hydrotalcite film became integral after being treated for 30 min. The results of polarization curves showed that the anti-corrosive performance of the hydrotalcite film was enhanced by the sealing treatment. Moreover, the immersion tests and electrochemical impedance spectrum measurements also demonstrated that the sealed hydrotalcite film provided a longer-term protection of magnesium alloy from corrosion as compared to the unsealed one.
基金This research was funded by National Natural Science Foundation of China （51275026） and State Key Laboratory of Development and Application Technology of Automotive Steels （Bao Steel Y 12ECEQ07Y）.
文摘The biaxial tensile tests were carried out to investigate the deformation behavior and yield loci of dual-phase （DP） steel sheets under biaxial tensile conditions. The true stress-true strain curves of DP steel sheets for different loading ratios were obtained, and the experimental yield loci were determined based on the equivalent plastic work principle. The experimental yield loci were compared to the theoretical yield loci based on Hi1148, Hi1190, Hi1193, Hosford, Barlat89, Yld2000-2d and Gotoh yield criteria. It is found that Yld2000-2d yield criterion can describe the general trends of experimental yield loci of DP steel sheets with comparably higher accuracy. Hosford criterion has the maximum error for DP590, whereas Hi1148 and Barlat89 have the maximum errors for DP780 and DP980.
