To the Editor:Rheumatoid arthritis(RA)is a chronic inflammatory disease characterized by an excess of cardiovascular disease(CVD)risk,estimated to be at least 50%greater than the general population.[1]CVD has been rec...To the Editor:Rheumatoid arthritis(RA)is a chronic inflammatory disease characterized by an excess of cardiovascular disease(CVD)risk,estimated to be at least 50%greater than the general population.[1]CVD has been recognized as the main cause of mortality in established RA patients,but recent data confirm this trend also in earlier stages of the disease.[2]Several factors have been evoked as determinants of this additional risk,but the most consolidated theory attributes this phenomenon to the interplay between chronic high-grade inflammation and elevated prevalence of“classical”cardiovascular risk factors,including diabetes.展开更多
基金Shanghai Health and Family Planning Program(No. 201604303)
文摘To the Editor:Rheumatoid arthritis(RA)is a chronic inflammatory disease characterized by an excess of cardiovascular disease(CVD)risk,estimated to be at least 50%greater than the general population.[1]CVD has been recognized as the main cause of mortality in established RA patients,but recent data confirm this trend also in earlier stages of the disease.[2]Several factors have been evoked as determinants of this additional risk,but the most consolidated theory attributes this phenomenon to the interplay between chronic high-grade inflammation and elevated prevalence of“classical”cardiovascular risk factors,including diabetes.
