Pd-catalyzed oxidative homocoupling of 2-arylquinazolinones was successfully developed for the direct construction of biaryls via C—H bond activation.New well-defined structure that possessed two quinazolinone units ...Pd-catalyzed oxidative homocoupling of 2-arylquinazolinones was successfully developed for the direct construction of biaryls via C—H bond activation.New well-defined structure that possessed two quinazolinone units was obtained with high efficiency and atomic economy.The protocols offer an efficient approach to the synthetically useful and functionalized biaryls in good yields using quinazolinone as a directing group.展开更多
基金the National Natural Science Foundation of China(No.21572072)111 Project(No.BC2018061)and Y.Feng thanks the financial support of Scientific Research Foundation of Xiamen Huaxia University(No.HX201807)+1 种基金Outstanding Youth Scientific Research Cultivation Plan in Fujian Province University(No.201808)the Fujian Education and Scientific Research Project for Young and Middle-aged Teachers(No.JAT190990)。
文摘Pd-catalyzed oxidative homocoupling of 2-arylquinazolinones was successfully developed for the direct construction of biaryls via C—H bond activation.New well-defined structure that possessed two quinazolinone units was obtained with high efficiency and atomic economy.The protocols offer an efficient approach to the synthetically useful and functionalized biaryls in good yields using quinazolinone as a directing group.