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Intestinal tryptophan metabolism in disease prevention and swine production
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作者 zhenguo hu Luya Feng +4 位作者 Qian Jiang Wenliang Wang Bi'e Tan Xiongzhuo Tang Yulong Yin 《Animal Nutrition》 SCIE CAS CSCD 2023年第4期364-374,共11页
Tryptophan(Trp)is an essential amino acid that cannot be synthesized by animals.It has been characterized into two different isomers,levorotation-Trp(L-Trp)and dextrorotation-Trp(D-Trp),based on their distinct molecul... Tryptophan(Trp)is an essential amino acid that cannot be synthesized by animals.It has been characterized into two different isomers,levorotation-Trp(L-Trp)and dextrorotation-Trp(D-Trp),based on their distinct molecule orientation.Intestinal epithelial cells and gut microbiota are involved in metabolizing L-Trp in the gut via the activation of the kynurenine,serotonin,and indole pathways.However,knowledge regarding D-Trp metabolism in the gut remains unclear.In this review,we briefly update the current understanding of intestinal L/D-Trp metabolism and the function of their metabolites in modulating the gut physiology and diseases.Finally,we summarize the effects of Trp nutrition on swine production at different stages,including growth performance in weaned piglets and growing pigs,as well as the reproduction performance in sows. 展开更多
关键词 Tryptophan metabolism Gut microbiota DISEASES Swine production
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