Fallopia multiflora(Thunb.)Harald,a vine belonging to the Polygonaceae family,is used in traditional medicine.The stilbenes contained in it have significant pharmacological activities in anti-oxidation and anti-aging....Fallopia multiflora(Thunb.)Harald,a vine belonging to the Polygonaceae family,is used in traditional medicine.The stilbenes contained in it have significant pharmacological activities in anti-oxidation and anti-aging.This study describes the assembly of the F.multiflora genome and presents its chromosome-level genome sequence containing 1.46 gigabases of data(with a contig N50 of 1.97 megabases),1.44 gigabases of which was assigned to 11 pseudochromosomes.Comparative genomics confirmed that F.multiflora shared a whole-genome duplication event with Tartary buckwheat and then underwent different transposon evolution after separation.Combining genomics,transcriptomics,and metabolomics data to map a network of associated genes and metabolites,we identified two FmRS genes responsible for the catalysis of one molecule of p-coumaroyl-CoA and three molecules of malonyl-CoA to resveratrol in F.multiflora.These findings not only serve as the basis for revealing the stilbene biosynthetic pathway but will also contribute to the development of tools for increasing the production of bioactive stilbenes through molecular breeding in plants or metabolic engineering in microbes.Moreover,the reference genome of F.multiflora is a useful addition to the genomes of the Polygonaceae family.展开更多
A Hamiltonian-based analytical method is used to study the mode Ⅲ interface cracks in magnetoelectroelastic bimaterials with an imperfect interface. By introducing an unknown vector, the governing equations are refor...A Hamiltonian-based analytical method is used to study the mode Ⅲ interface cracks in magnetoelectroelastic bimaterials with an imperfect interface. By introducing an unknown vector, the governing equations are reformulated in sets of first-order ordinary differential equations. Using separation of variables, eigensolutions in the symplectic space are obtained. An exact solution of the unknown vector is obtained and expressed in terms of symplectic eigensolutions. Singularities of mechanical, electric, and magnetic fields are evaluated with the generalized intensity factors. Comparisons are made to verify accuracy and stability of the proposed method. Numerical examples including mixed boundary conditions are given.展开更多
In this paper,a local surface nanocrystallization technology is used for thin-walled structures with square cross sections,and an energy absorption device of two-staged combined energy absorption structure is proposed...In this paper,a local surface nanocrystallization technology is used for thin-walled structures with square cross sections,and an energy absorption device of two-staged combined energy absorption structure is proposed.In virtue of the surface nanocrystallization that enables to change the material on local positions,the structural deformation is induced and controlled to maximize the energy absorption capacity.A numerical model of the two-staged combined energy absorption structure is established,and the local surface nanocrystallization layout is optimized.The results show that the specific energy absorption of two-staged combined structure with local surface nanocrystallization can be increased by 34.36%compared with the untreated counterpart of the same material and structural shape.The ratio between the first and second peak crushing forces and the energy absorption allocation ratio between the two stages can be adjusted in the ranges of 0.26–0.55 and 0.31–0.45,respectively,which can be controlled by the local surface nanocrystallization designs.The numerical simulation and experimental results are in good agreement,which shows that the design for energy absorption device with local surface nanocrystallization is feasible and effective.展开更多
基金This study was funded by the National Natural Science Foundation of China(No.81973432)the Major Increase and Reduction Project at the Central Level(No.2060302)+1 种基金Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-D-202005)CAMS Innovation Fund for Medical Sciences(2019-I2M-5-065).
文摘Fallopia multiflora(Thunb.)Harald,a vine belonging to the Polygonaceae family,is used in traditional medicine.The stilbenes contained in it have significant pharmacological activities in anti-oxidation and anti-aging.This study describes the assembly of the F.multiflora genome and presents its chromosome-level genome sequence containing 1.46 gigabases of data(with a contig N50 of 1.97 megabases),1.44 gigabases of which was assigned to 11 pseudochromosomes.Comparative genomics confirmed that F.multiflora shared a whole-genome duplication event with Tartary buckwheat and then underwent different transposon evolution after separation.Combining genomics,transcriptomics,and metabolomics data to map a network of associated genes and metabolites,we identified two FmRS genes responsible for the catalysis of one molecule of p-coumaroyl-CoA and three molecules of malonyl-CoA to resveratrol in F.multiflora.These findings not only serve as the basis for revealing the stilbene biosynthetic pathway but will also contribute to the development of tools for increasing the production of bioactive stilbenes through molecular breeding in plants or metabolic engineering in microbes.Moreover,the reference genome of F.multiflora is a useful addition to the genomes of the Polygonaceae family.
基金Project supported by the National Natural Science Foundation of China(Nos.11672054 and11372070)the National Basic Research Program of China(973 Program)(No.2014CB046803)
文摘A Hamiltonian-based analytical method is used to study the mode Ⅲ interface cracks in magnetoelectroelastic bimaterials with an imperfect interface. By introducing an unknown vector, the governing equations are reformulated in sets of first-order ordinary differential equations. Using separation of variables, eigensolutions in the symplectic space are obtained. An exact solution of the unknown vector is obtained and expressed in terms of symplectic eigensolutions. Singularities of mechanical, electric, and magnetic fields are evaluated with the generalized intensity factors. Comparisons are made to verify accuracy and stability of the proposed method. Numerical examples including mixed boundary conditions are given.
基金In this research work,the Aeronautical Science Foundation of China(2018ZC63003)State Key Laboratory of Structural Analysis for Industrial Equipment(G19109,S18313)are gratefully acknowledged.
文摘In this paper,a local surface nanocrystallization technology is used for thin-walled structures with square cross sections,and an energy absorption device of two-staged combined energy absorption structure is proposed.In virtue of the surface nanocrystallization that enables to change the material on local positions,the structural deformation is induced and controlled to maximize the energy absorption capacity.A numerical model of the two-staged combined energy absorption structure is established,and the local surface nanocrystallization layout is optimized.The results show that the specific energy absorption of two-staged combined structure with local surface nanocrystallization can be increased by 34.36%compared with the untreated counterpart of the same material and structural shape.The ratio between the first and second peak crushing forces and the energy absorption allocation ratio between the two stages can be adjusted in the ranges of 0.26–0.55 and 0.31–0.45,respectively,which can be controlled by the local surface nanocrystallization designs.The numerical simulation and experimental results are in good agreement,which shows that the design for energy absorption device with local surface nanocrystallization is feasible and effective.