Inflammatory myofibroblastic tumor(IMT) is rare in clinical practice.As its treatment mainly involves surgery,radiotherapy alone is seldom reported in literature.Here we report a case of lowly malignant cranial IMT wi...Inflammatory myofibroblastic tumor(IMT) is rare in clinical practice.As its treatment mainly involves surgery,radiotherapy alone is seldom reported in literature.Here we report a case of lowly malignant cranial IMT with intracranial invasion in a female patient. As surgery was not suitable,intensity modulated radiation therapy(IMRT) was administered.After radiotherapy,the cranial lesions tended to show efficacy.展开更多
Background:Sand fly Phlebotomus chinensis is a principle vector for the visceral leishmaniasis(VL)in China with a wide geographic distribution.Jiuzhaigou,Sichuan is a mountain type endemic area of VL in China.Long ter...Background:Sand fly Phlebotomus chinensis is a principle vector for the visceral leishmaniasis(VL)in China with a wide geographic distribution.Jiuzhaigou,Sichuan is a mountain type endemic area of VL in China.Long term effective control efforts in the region have successfully reduced VL transmission.To assess the current status of the sand flies and their ecological aspects in the region,a survey was conducted in the summer of 2014 and 2015.Methods:Sand fly specimens were collected by light traps in a village and blood sources were identified by PCR and sequencing of the mitochondrial cytochrome b gene.Results:In a rock cave,65.2%–79.8%of collected sand flies were male.On a rabbit farm,92.9%–98.8%of specimens were female.In pig pens,61.1%of specimens were female.Some females had visible blood residues.The feeding rate was 49.4%from the pig pens,12.3%from the cave,and only 1.7%from the rabbit farm.Pig,rabbit,chicken,dog,and human blood were detected in the fed specimens.Swine blood,present in all tested samples,was a preferred blood source,while chicken and dog blood were present in a third of the samples.Conclusions:In Jiuzhaigou County,Sichuan Province of China,the considerable sandfly density and the peridomestic feeding behavior all increases the risk of VL transmission,and insecticide spraying in animal sheds could be exploited to reduce sand fly populations in human surroundings.展开更多
During the past years,the recovery of unconventional gas formation has attracted lots of attention and achieved huge success.To produce gas from the low-permeability unconventional formations,hydraulic fracturing tech...During the past years,the recovery of unconventional gas formation has attracted lots of attention and achieved huge success.To produce gas from the low-permeability unconventional formations,hydraulic fracturing technology is essential and critical.In this paper,we present the development of a three-dimensional thermalhydraulic-mechanical numerical simulator for the simulation of hydraulic fracturing operations in tight sandstone reservoirs.Our simulator is based on integrated finite difference(IFD)method.In this method,the simulation domain is subdivided into sub domains and the governing equations are integrated over a sub domain with flux terms expressed as an integral over the sub domain boundary using the divergence theorem.Our simulator conducts coupled thermal-hydraulic-mechanical simulation of the initiation and extension of hydraulic fractures.It also calculates the mass/heat transport of injected hydraulic fluids as well as proppants.Our simulator is able to handle anisotropic formations with multiple layers.Our simulator has been validated by comparing with an analytical solution as well as Ribeiro and Sharma model.Our model can simulate fracture spacing effect on fracture profile when combining IFD with Discontinuous Displacement Method(DDM).展开更多
文摘Inflammatory myofibroblastic tumor(IMT) is rare in clinical practice.As its treatment mainly involves surgery,radiotherapy alone is seldom reported in literature.Here we report a case of lowly malignant cranial IMT with intracranial invasion in a female patient. As surgery was not suitable,intensity modulated radiation therapy(IMRT) was administered.After radiotherapy,the cranial lesions tended to show efficacy.
基金supported by the YM’s grant 81371848 from the National Natural Sciences Foundation of ChinaJX’s grants SC1GM109367 from the National Institute Of Allergy And Infectious Diseases of the National Institutes of Health and the DMS-1222592 from National Science Foundation.
文摘Background:Sand fly Phlebotomus chinensis is a principle vector for the visceral leishmaniasis(VL)in China with a wide geographic distribution.Jiuzhaigou,Sichuan is a mountain type endemic area of VL in China.Long term effective control efforts in the region have successfully reduced VL transmission.To assess the current status of the sand flies and their ecological aspects in the region,a survey was conducted in the summer of 2014 and 2015.Methods:Sand fly specimens were collected by light traps in a village and blood sources were identified by PCR and sequencing of the mitochondrial cytochrome b gene.Results:In a rock cave,65.2%–79.8%of collected sand flies were male.On a rabbit farm,92.9%–98.8%of specimens were female.In pig pens,61.1%of specimens were female.Some females had visible blood residues.The feeding rate was 49.4%from the pig pens,12.3%from the cave,and only 1.7%from the rabbit farm.Pig,rabbit,chicken,dog,and human blood were detected in the fed specimens.Swine blood,present in all tested samples,was a preferred blood source,while chicken and dog blood were present in a third of the samples.Conclusions:In Jiuzhaigou County,Sichuan Province of China,the considerable sandfly density and the peridomestic feeding behavior all increases the risk of VL transmission,and insecticide spraying in animal sheds could be exploited to reduce sand fly populations in human surroundings.
文摘During the past years,the recovery of unconventional gas formation has attracted lots of attention and achieved huge success.To produce gas from the low-permeability unconventional formations,hydraulic fracturing technology is essential and critical.In this paper,we present the development of a three-dimensional thermalhydraulic-mechanical numerical simulator for the simulation of hydraulic fracturing operations in tight sandstone reservoirs.Our simulator is based on integrated finite difference(IFD)method.In this method,the simulation domain is subdivided into sub domains and the governing equations are integrated over a sub domain with flux terms expressed as an integral over the sub domain boundary using the divergence theorem.Our simulator conducts coupled thermal-hydraulic-mechanical simulation of the initiation and extension of hydraulic fractures.It also calculates the mass/heat transport of injected hydraulic fluids as well as proppants.Our simulator is able to handle anisotropic formations with multiple layers.Our simulator has been validated by comparing with an analytical solution as well as Ribeiro and Sharma model.Our model can simulate fracture spacing effect on fracture profile when combining IFD with Discontinuous Displacement Method(DDM).
