Synthesis of a New Chiral Ligand Containing 1, 5-Diazacyclooctane and the Application in Diethyl Zinc Addition to Benzaldehyde

A new chiral tetradentate ligand (S, S)-1, 5-bis (4-benzyloxazolin-2-yl-methyl)-1, 5-diazacyclo-octane 1 has been synthesized and the application of 1 as catalyst in the enantioselective addition of diethyl zinc to benzaldehyde is also described.

Synthesis of (S,S)-1,5-bis(4-alkyl-5-hydroxy-2-oxo-3-azapentyl)-1,5-diazacyclooctane

Synthesis of a series of chiral aza crown ethers ((S,S)-1, 5-bis (4-alkyl-5-hydroxy- 2-oxo-3-azapentyl)-1, 5-diazacyclooctane) are described.