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左旋多巴联合视觉刺激训练治疗青少年屈光不正性弱视 被引量:7
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作者 贺志华 李炎 张丽 《国际眼科杂志》 CAS 北大核心 2018年第6期1163-1165,共3页
目的:探讨应用左旋多巴和视觉刺激训练治疗青少年屈光不正性弱视的研究效果。方法:选取2013-05/2016-05在我院接受治疗的青少年屈光不正性弱视64例68眼进行本次研究,将其按数字表法随机分成观察组(32例33眼)与对照组(32例35眼)。对照组... 目的:探讨应用左旋多巴和视觉刺激训练治疗青少年屈光不正性弱视的研究效果。方法:选取2013-05/2016-05在我院接受治疗的青少年屈光不正性弱视64例68眼进行本次研究,将其按数字表法随机分成观察组(32例33眼)与对照组(32例35眼)。对照组采取视觉刺激训练疗法,观察组在对照组的基础上给予左旋多巴治疗。24wk后比较两组的临床效果以及治疗前后P-VEP、视觉敏感度的变化。结果:治疗24wk结束后,观察组的总有效率(91%)明显高于对照组(71%),差异有统计学意义(P<0.05);虽然对照组的P-VEP P100波幅升高,潜伏期缩短,但观察组的效果更显著,差异有统计学意义(P<0.05)。结论:左旋多巴和视觉刺激训练联合治疗青少年屈光不正性弱视的效果显著,能够较好地纠正其视觉敏感度,改善视神经传导功能。 展开更多
关键词 屈光不正性弱视 左旋多巴 视觉刺激训练 青少年
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Active feedback control of sound radiation in elastic wave metamaterials immersed in water with fluid-solid coupling 被引量:3
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作者 zhi-hua he Yi-Ze Wang Yue-Sheng Wang 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2021年第5期803-825,I0002,共24页
Due to their potential properties unlike traditional materials and structures,elastic wave metamaterials have received significant interests in recent years.With the coupling between the acoustic and vibration,their m... Due to their potential properties unlike traditional materials and structures,elastic wave metamaterials have received significant interests in recent years.With the coupling between the acoustic and vibration,their mechanical characteristics can be tuned by the active feedback control system at low frequency ranges in which the traditional passive control is limited.This work illustrates that the superior performances of the effective mass density and sound pressure level(SPL)of an elastic wave metamaterial can be significantly changed by the active control,in which the periodic array of local resonators and orthogonal stiffeners are included.Significantly,based on the locally resonant mechanism,the negative density occurs over a frequency range.Due to the effects of lattice constant,structural damping and other parameters,the SPL with the function of fluid-solid coupling are illustrated and discussed. 展开更多
关键词 Elastic wave metamaterial Local resonance Sound radiation Fluid-solid coupling Active feedback control
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Sound Transmission Comparisons of Active Elastic Wave Metamaterial Immersed in External Mean Flow 被引量:3
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作者 zhi-hua he Yi-Ze Wang Yue-Sheng Wang 《Acta Mechanica Solida Sinica》 SCIE EI CSCD 2021年第3期307-325,共19页
Using the active feedback control system on the elastic wave metamaterial,this research concentrates on the sound transmission with the dynamic effective model.The metamaterial is subjected to an incident pressure and... Using the active feedback control system on the elastic wave metamaterial,this research concentrates on the sound transmission with the dynamic effective model.The metamaterial is subjected to an incident pressure and immersed in the external mean flow.The elastic wave metamaterial consists of double plates and the upper and lower four-link mechanisms are attached inside.The vertical resonator is attached by the active feedback control system and connected with two four-link mechanisms.Based on the dynamic equivalent method,the metamaterial is equivalent as a single-layer plate by the dynamic effective parameter.With the coupling between the fluid and structure,the expression of the sound transmission loss(STL)is derived.This research shows the influence of effective mass density on sound transmission properties,and the STL in both modes can be tuned by the acceleration and displacement feedback constants.In addition,the dynamic response and the STL are also changed obviously by different values of structural damping,incident angle(i.e.,the elevation and azimuth angles)and Mach number of the external fluid with the mean flow property.The results for sound transmission by two methods are compared,i.e.,the virtual work principle for double plates and the dynamic equivalent method corresponding to a single one.This paper is expected to be helpful for understanding the sound transmission properties of both pure single-and double-plate models. 展开更多
关键词 Elastic wave metamaterials Active feedback control Dynamic equivalent method Sound transmission External mean flow
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Extraction and verification of miRNA from ginseng decoction 被引量:2
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作者 Ying-fang Wang Wen-juan Wang +5 位作者 Yan-lin Chen zhi-hua he Jing-jing Cao Ze-min Yang Meng-juan Gong Yong-qin Yin 《Chinese Herbal Medicines》 CAS 2018年第3期318-322,共5页
Objective: To verify the existence of microRNAs(miRNAs) extracted from fresh ginseng decoction.Methods: Fresh ginseng was prepared into decoction according to the conventional method. The miRNA were extracted from the... Objective: To verify the existence of microRNAs(miRNAs) extracted from fresh ginseng decoction.Methods: Fresh ginseng was prepared into decoction according to the conventional method. The miRNA were extracted from the condensed ginseng decoction by plant microRNA extraction kit. Then miRNA were treated by DNase I and subjected to agarose gel electrophoresis and Agilent 2100 bioanalysis. Mi R-159 and mi R-6135, which were highly expressed in ginseng, were selected and verified by real-time quantitative PCR to detect the expression in the decoction.Results: Ginseng miRNA were successfully extracted from fresh decoction. Mi R-159 and mi R-6135 were expressed in fresh decoction with lower levels than those of fresh ginseng.Conclusion: miRNAs stably existed after processing, and retained some stability after high-temperature treatment. The findings provide a valuables basis for the further studies on ginseng miRNAs. 展开更多
关键词 fresh ginseng MIRNA miR-159 miR-6135 real-time quantitative PCR water decoction
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