To further improve the ability of pre-hospital and in-hospital collaborative treatment, strengthen emergency multidisciplinary cooperation and construct a scientific, rational and efficient emergency system, under the...To further improve the ability of pre-hospital and in-hospital collaborative treatment, strengthen emergency multidisciplinary cooperation and construct a scientific, rational and efficient emergency system, under the support of former chairman Yu Xue-zhong, Dr. Li Chun-sheng and numerous colleagues in the industry, the Emergency Medicine Society of the Chinese Medical Association appeal to us to draft Construction of Emergency and Pre-hospital Platform. Based on this background, the platform of emergency and pre-hospital first aid helps to build a 'one horizontal and one Longitudinal' treatment model, using the horizontal and longitudinal patterns to integrate emergency medical resources to satisfy the automatic information integration and intelligent analysis sharing, realizing the emergency management visualization and medical information digitization, simplifying the medical process and establishing a perfect standard for the emergent diseases, thereby ultimately achieving efficient diagnosis and scientific treatment.展开更多
Sepsis is a syndrome characterized by systemic inflammatory response caused by infection or toxin, with high morbidity and mortality. Different infection microflora and environment have great influence on the occurren...Sepsis is a syndrome characterized by systemic inflammatory response caused by infection or toxin, with high morbidity and mortality. Different infection microflora and environment have great influence on the occurrence, development and prognosis of sepsis, but individual genetic factors also play an extremely important role. It was reported that the polymorphisms of mannose-binding lectin 2 gene were closely relevant to the occurrence and development of sepsis, but the conclusions in different studies were inconsistent. Therefore, we performed this reviews on the relevance of mannose-binding lectin 2 gene polymorphisms and sepsis.展开更多
The epidemic caused by the new coronavirus infection is a global public health emergency. The new coronavirus pneumonia (COVID-19) has caused more deaths in China than the SARS-CoV outbreak in 2003. Since the virus ha...The epidemic caused by the new coronavirus infection is a global public health emergency. The new coronavirus pneumonia (COVID-19) has caused more deaths in China than the SARS-CoV outbreak in 2003. Since the virus has a high homology with SARS-CoV, it is speculates that it may infect cells through the S protein-ACE2 pathway then cause tracheal epithelial cell damage and alveolar damage, further induce inflammatory factor storm and trigger apoptosis cascade reaction and other mechanisms leading to acute lung injury. At early stage, the new coronavirus pneumonia mainly presents with non-specific manifestations of fatigue, fever, cough, etc., Then the respiratory tract will be involved, and evolved into the new type of infectious disease with lung lesions. Under radiology images, ground glass-like changes can be observed in the lungs. With its aggravation, progressive hypoxemia, acute respiratory distress syndrome, and even death occurs. At present, the correlation between the new coronavirus pneumonia and acute lung injury is not yet clear. This article reviews the characteristics of the new coronavirus, the possible mechanism of acute lung injury in new coronavirus pneumonia, post-infection diagnosis and current treatment options in order to provide evidence for its treatment.展开更多
1.Introduction Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac causes.It is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symp...1.Introduction Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac causes.It is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].展开更多
文摘To further improve the ability of pre-hospital and in-hospital collaborative treatment, strengthen emergency multidisciplinary cooperation and construct a scientific, rational and efficient emergency system, under the support of former chairman Yu Xue-zhong, Dr. Li Chun-sheng and numerous colleagues in the industry, the Emergency Medicine Society of the Chinese Medical Association appeal to us to draft Construction of Emergency and Pre-hospital Platform. Based on this background, the platform of emergency and pre-hospital first aid helps to build a 'one horizontal and one Longitudinal' treatment model, using the horizontal and longitudinal patterns to integrate emergency medical resources to satisfy the automatic information integration and intelligent analysis sharing, realizing the emergency management visualization and medical information digitization, simplifying the medical process and establishing a perfect standard for the emergent diseases, thereby ultimately achieving efficient diagnosis and scientific treatment.
基金National Natural Science Foundation of China(81860347)Hainan Provincial Natural Science Foundation of China(818MS140)+2 种基金Young Talents'Science and Technology Innovation Project of Hainan Association for Science and Technology(QCXM201816)Hainan Provincial Health and Family Planning Commission Project(18A200178)Undergraduate Innovative Experiment Project of Hainan Medical University(HYCX2018122).
文摘Sepsis is a syndrome characterized by systemic inflammatory response caused by infection or toxin, with high morbidity and mortality. Different infection microflora and environment have great influence on the occurrence, development and prognosis of sepsis, but individual genetic factors also play an extremely important role. It was reported that the polymorphisms of mannose-binding lectin 2 gene were closely relevant to the occurrence and development of sepsis, but the conclusions in different studies were inconsistent. Therefore, we performed this reviews on the relevance of mannose-binding lectin 2 gene polymorphisms and sepsis.
基金AHQDS study on the treatment of paraquat poisoning(ZDYF2019125)Midkine on the proliferation of airway smooth muscle cels in SD rat COPD model and its molecular mechanism(81660011)CAMS Innovation Fund for Medical Sciences(2019-I2M-5-023)
文摘The epidemic caused by the new coronavirus infection is a global public health emergency. The new coronavirus pneumonia (COVID-19) has caused more deaths in China than the SARS-CoV outbreak in 2003. Since the virus has a high homology with SARS-CoV, it is speculates that it may infect cells through the S protein-ACE2 pathway then cause tracheal epithelial cell damage and alveolar damage, further induce inflammatory factor storm and trigger apoptosis cascade reaction and other mechanisms leading to acute lung injury. At early stage, the new coronavirus pneumonia mainly presents with non-specific manifestations of fatigue, fever, cough, etc., Then the respiratory tract will be involved, and evolved into the new type of infectious disease with lung lesions. Under radiology images, ground glass-like changes can be observed in the lungs. With its aggravation, progressive hypoxemia, acute respiratory distress syndrome, and even death occurs. At present, the correlation between the new coronavirus pneumonia and acute lung injury is not yet clear. This article reviews the characteristics of the new coronavirus, the possible mechanism of acute lung injury in new coronavirus pneumonia, post-infection diagnosis and current treatment options in order to provide evidence for its treatment.
基金Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(No.2019-I2M-5-023)Hainan Provincial Science and Technology Major Project(No.ZDKJ201804)+2 种基金National Natural Science Foundation of China(No.81871611)National Natural Science Foundation of China(No.81760352)Project of Hainan Provincial Department of Education(No.Hnjg2019ZD-16)
文摘1.Introduction Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac causes.It is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].