Oral squamous cell carcinoma (OSCC) has a high incidence of cervical micrometastases and sometimes metastasizes contralaterally because of the rich lymphatic intercommunications relative to submucosal plexus of oral...Oral squamous cell carcinoma (OSCC) has a high incidence of cervical micrometastases and sometimes metastasizes contralaterally because of the rich lymphatic intercommunications relative to submucosal plexus of oral cavity that freely communicate across the midline, and it can facilitate the spread of neoplastic cells to any area of the neck consequently. Clinical and histopathologic factors continue to provide predictive information to contralateral neck metastases (CLNM) in OSCC, which determine prophylactic and adjuvant treatments for an individual patient. This review describes the predictive value of clinical-histopathologic factors, which relate to primary tumor and cervical lymph nodes, and surgical dissection and adjuvant treatments. In addition, the indications for elective contralateral neck dissection and adjuvant radiotherapy (aRT) and strategies for follow-up are offered, which is strongly focused by clinicians to prevent later CLNM and poor prognosis subsequently.展开更多
Currently, when magnesium alloy sheet is rolled, the method of controlling roll temperature is simple and inaccurate. Furthermore, roll temperature has a large influence on the quality of magnesium alloy sheet; theref...Currently, when magnesium alloy sheet is rolled, the method of controlling roll temperature is simple and inaccurate. Furthermore, roll temperature has a large influence on the quality of magnesium alloy sheet; therefore, a new model using circular fluid flow control roll temperature has been designed. A fluid heat transfer structure was designed, the heat transfer process model of the fluid heating roll was simplified, and the finite di erence method was used to cal?culate the heat transfer process. Fluent software was used to simulate the fluid?solid coupling heat transfer, and both the trend and regularity of the temperature field in the heat transfer process were identified. The results show that the heating e ciency was much higher than traditional heating methods(when the fluid heat of the roll and tempera?ture distribution of the roll surface was more uniform). Moreover, there was a bigger temperature di erence between the input and the output, and after using reverse flow the temperature di erence decreased. The axial and circum?ferential temperature distributions along the sheet were uniform. Both theoretical calculation results and numerical simulation results of the heat transfer between fluid and roll were compared. The error was 1.8%–12.3%, showing that the theoretical model can both forecast and regulate the temperature of the roll(for magnesium alloy sheets) in the rolling process.展开更多
The search for novel materials with new functionalities and applications potential is continuing to intensify.Quantum anomalous Hall(QAH)effect was recently realized in magnetic topological insulators(TIs)but only at ...The search for novel materials with new functionalities and applications potential is continuing to intensify.Quantum anomalous Hall(QAH)effect was recently realized in magnetic topological insulators(TIs)but only at extremely low temperatures.Here,based on our first-principles electronic structure calculations,we predict that chemically functionalized Ⅲ-Bi honeycombs can support large-gap QAH insulating phases.Specifically,we show that functionalized AlBi and TlBi films harbor QAH insulator phases.GaBi and InBi are identified as semimetals with non-zero Chern number.Remarkably,TlBi exhibits a robust QAH phase with a band gap as large as 466 meV in a buckled honeycomb structure functionalized on one side.Furthermore,the electronic spectrum of a functionalized TlBi nanoribbon with zigzag edge is shown to possess only one chiral edge band crossing the Fermi level within the band gap.Our results suggest that Ⅲ-Bi honeycombs would provide a new platform for developing potential spintronics applications based on the QAH effect.展开更多
基金supported by the National Key Research and Development Program of China(No.2018YFA0707300)the General Program of National Natural Science Foundation of China(No.51905372)+1 种基金the Key Project of Shanxi Province,China(No.20181101008)the Postdoctoral Science Foundation of China(No.2020T130463)。
基金Projects(51501122,51604181) supported by the National Natural Science Foundation of ChinaProject(20172009) supported by the Postdoctoral Sustentation Fund of Taiyuan University of Science and Technology,China+3 种基金Project(20132016) supported by the Research Fund for the Doctoral Program of Higher Education of ChinaProject(201501004-8) supported by the Jincheng Science and Technology Plan Project,ChinaProject(U1510131) supported by NSFC-Shanxi Coal-based Low-carbon United Fund and"Shanxi Young Scholars"Program,ChinaProject(201603D121010) supported by Key R&D Program of Shanxi Province,China
文摘Oral squamous cell carcinoma (OSCC) has a high incidence of cervical micrometastases and sometimes metastasizes contralaterally because of the rich lymphatic intercommunications relative to submucosal plexus of oral cavity that freely communicate across the midline, and it can facilitate the spread of neoplastic cells to any area of the neck consequently. Clinical and histopathologic factors continue to provide predictive information to contralateral neck metastases (CLNM) in OSCC, which determine prophylactic and adjuvant treatments for an individual patient. This review describes the predictive value of clinical-histopathologic factors, which relate to primary tumor and cervical lymph nodes, and surgical dissection and adjuvant treatments. In addition, the indications for elective contralateral neck dissection and adjuvant radiotherapy (aRT) and strategies for follow-up are offered, which is strongly focused by clinicians to prevent later CLNM and poor prognosis subsequently.
基金National Natural Science Foundation of China(Grant No.U1510131)Key Research and Development Projects of Shanxi Province of China(Grant Nos.201603D121010,201603D111004)+3 种基金Science and Technology Project of Jin Cheng City of China(Grant No.20155010)Youth Program of National Natural Science Fund of China(Grant No.51604181)Project of Young Scholar of Shanxi ProvinceLeading Talent Project of Innovative Entrepreneurial Team of Jiangsu Province(Grant No.51501122)
文摘Currently, when magnesium alloy sheet is rolled, the method of controlling roll temperature is simple and inaccurate. Furthermore, roll temperature has a large influence on the quality of magnesium alloy sheet; therefore, a new model using circular fluid flow control roll temperature has been designed. A fluid heat transfer structure was designed, the heat transfer process model of the fluid heating roll was simplified, and the finite di erence method was used to cal?culate the heat transfer process. Fluent software was used to simulate the fluid?solid coupling heat transfer, and both the trend and regularity of the temperature field in the heat transfer process were identified. The results show that the heating e ciency was much higher than traditional heating methods(when the fluid heat of the roll and tempera?ture distribution of the roll surface was more uniform). Moreover, there was a bigger temperature di erence between the input and the output, and after using reverse flow the temperature di erence decreased. The axial and circum?ferential temperature distributions along the sheet were uniform. Both theoretical calculation results and numerical simulation results of the heat transfer between fluid and roll were compared. The error was 1.8%–12.3%, showing that the theoretical model can both forecast and regulate the temperature of the roll(for magnesium alloy sheets) in the rolling process.
基金support from the National Center for Theoretical Sciences and the Ministry of Science and Technology of Taiwan under Grants Nos.MOST-104-2112-M-110-002-MY3 and MOST-103-2112-M-110-008-MY3the support under NSYSU-NKMU JOINT RESEARCH PROJECT#105-P005 and#106-P005+3 种基金supported by the US Department of Energy(DOE),Office of Science,Basic Energy Sciences grant number DE-FG02-07ER46352(core research)benefited from Northeastern University’s Advanced Scientific Computation Center(ASCC),the NERSC supercomputing center through DOE grant number DE-AC02-05CH11231support(applications to layered materials)from the DOE EFRC:Center for the Computational Design of Functional Layered Materials(CCDM)under DE-SC0012575the Singapore National Research Foundation for support under NRF Award No.NRFNRFF2013-03.
文摘The search for novel materials with new functionalities and applications potential is continuing to intensify.Quantum anomalous Hall(QAH)effect was recently realized in magnetic topological insulators(TIs)but only at extremely low temperatures.Here,based on our first-principles electronic structure calculations,we predict that chemically functionalized Ⅲ-Bi honeycombs can support large-gap QAH insulating phases.Specifically,we show that functionalized AlBi and TlBi films harbor QAH insulator phases.GaBi and InBi are identified as semimetals with non-zero Chern number.Remarkably,TlBi exhibits a robust QAH phase with a band gap as large as 466 meV in a buckled honeycomb structure functionalized on one side.Furthermore,the electronic spectrum of a functionalized TlBi nanoribbon with zigzag edge is shown to possess only one chiral edge band crossing the Fermi level within the band gap.Our results suggest that Ⅲ-Bi honeycombs would provide a new platform for developing potential spintronics applications based on the QAH effect.