Vascular injuries can lead to severe consequences, and in particular, carotid artery injury caused by combat, traffic accidents or other external forces is extremely harmful. As the neck has a complex anatomical struc...Vascular injuries can lead to severe consequences, and in particular, carotid artery injury caused by combat, traffic accidents or other external forces is extremely harmful. As the neck has a complex anatomical structure and a relatively small local space, carotid artery injury is usually complicated by neural and spinal injuries.展开更多
Parkinson’s disease(PD)is characterized by pathological spontaneous beta oscillations(13 Hz-35 Hz)often observed in basal ganglia(BG)composed of subthalamic nucleus(STN)and globus pallidus(GPe)populations.From the vi...Parkinson’s disease(PD)is characterized by pathological spontaneous beta oscillations(13 Hz-35 Hz)often observed in basal ganglia(BG)composed of subthalamic nucleus(STN)and globus pallidus(GPe)populations.From the viewpoint of dynamics,the spontaneous oscillations are related to limit cycle oscillations in a nonlinear system;here we employ the bifurcation analysis method to elucidate the generating mechanism of the pathological spontaneous beta oscillations underlined by coupling strengths and intrinsic properties of the STN-GPe circuit model.The results reveal that the increase of inter-coupling strength between STN and GPe populations induces the beta oscillations to be generated spontaneously,and causes the oscillation frequency to decrease.However,the increase of intra-coupling(self-feedback)strength of GPe can prevent the model from generating the oscillations,and dramatically increase the oscillation frequency.We further provide a theoretical explanation for the role played by the inter-coupling strength of GPe population in the generation and regulation of the oscillations.Furthermore,our study reveals that the intra-coupling strength of the GPe population provides a switching mechanism on the generation of the abnormal beta oscillations:for small value of the intra-coupling strength,STN population plays a dominant role in inducing the beta oscillations;while for its large value,the GPe population mainly determines the generation of this oscillation.展开更多
ZnO bicrystalline nanosheets have been synthesized by using Ax=AU1-x alloy catalyst via the vapor transport and condensation method at 650 ℃. High resolution transmission electron microscopy characterization reveals ...ZnO bicrystalline nanosheets have been synthesized by using Ax=AU1-x alloy catalyst via the vapor transport and condensation method at 650 ℃. High resolution transmission electron microscopy characterization reveals a twin boundary with {01-13} plane existing in the bicrystalline. A series of control experiments show that both AgxAu1-x alloy catalyst and high supersaturation of Zn vapor are prerequisites for the formation of ZnO bicrystalline nanosheet. Moreover, it is found that the density of ZnO bicrytalline nanosheets can be tuned through varying the ratio of Ag to Au in the alloy catalyst. The result demonstrates that new complicated nanostructures can be produced controllably with appropriate alloy catalyst.展开更多
文摘Vascular injuries can lead to severe consequences, and in particular, carotid artery injury caused by combat, traffic accidents or other external forces is extremely harmful. As the neck has a complex anatomical structure and a relatively small local space, carotid artery injury is usually complicated by neural and spinal injuries.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61473208 and 61876132)the Tianjin Research Program of Application Foundation and Advanced Technology,China(Grant No.15JCYBJC47700).
文摘Parkinson’s disease(PD)is characterized by pathological spontaneous beta oscillations(13 Hz-35 Hz)often observed in basal ganglia(BG)composed of subthalamic nucleus(STN)and globus pallidus(GPe)populations.From the viewpoint of dynamics,the spontaneous oscillations are related to limit cycle oscillations in a nonlinear system;here we employ the bifurcation analysis method to elucidate the generating mechanism of the pathological spontaneous beta oscillations underlined by coupling strengths and intrinsic properties of the STN-GPe circuit model.The results reveal that the increase of inter-coupling strength between STN and GPe populations induces the beta oscillations to be generated spontaneously,and causes the oscillation frequency to decrease.However,the increase of intra-coupling(self-feedback)strength of GPe can prevent the model from generating the oscillations,and dramatically increase the oscillation frequency.We further provide a theoretical explanation for the role played by the inter-coupling strength of GPe population in the generation and regulation of the oscillations.Furthermore,our study reveals that the intra-coupling strength of the GPe population provides a switching mechanism on the generation of the abnormal beta oscillations:for small value of the intra-coupling strength,STN population plays a dominant role in inducing the beta oscillations;while for its large value,the GPe population mainly determines the generation of this oscillation.
基金ACKNOWLEDGMENTS This work was supported by the Ministry of Science and Technology of China of China (No.2011CB921403), the National Natural Science Foundation of China (No. 11374274 and No. 11074231), and Chinese Academy of Sciences (No.XDB01020000).
文摘ZnO bicrystalline nanosheets have been synthesized by using Ax=AU1-x alloy catalyst via the vapor transport and condensation method at 650 ℃. High resolution transmission electron microscopy characterization reveals a twin boundary with {01-13} plane existing in the bicrystalline. A series of control experiments show that both AgxAu1-x alloy catalyst and high supersaturation of Zn vapor are prerequisites for the formation of ZnO bicrystalline nanosheet. Moreover, it is found that the density of ZnO bicrytalline nanosheets can be tuned through varying the ratio of Ag to Au in the alloy catalyst. The result demonstrates that new complicated nanostructures can be produced controllably with appropriate alloy catalyst.