AIM To investigate the efficacy and safety of transcutaneouselectroacupuncture(TEA) to alleviate postoperative ileus(POI) after gastrectomy.METHODS From April 2014 to February 2017, 63 gastric cancer patients were rec...AIM To investigate the efficacy and safety of transcutaneouselectroacupuncture(TEA) to alleviate postoperative ileus(POI) after gastrectomy.METHODS From April 2014 to February 2017, 63 gastric cancer patients were recruited from the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China. After gastrectomy, the patients were randomly allocated to the TEA(n = 33) or control(n = 30) group. The patients in the TEA group received 1 h TEA on Neiguan(ST36) and Zusanli(PC6) twice daily in the morning and afternoon until they passed flatus. The main outcomes were hours to the first flatus or bowel movement, time to nasogastric tube removal, time to liquid and semi-liquid diet, and hospital stay. The secondary outcomes included postoperative symptom assessment and complications.RESULTS Time to first flatus in the TEA group was significantly shorter than in the control group(73.19 ± 15.61 vs 82.82 ± 20.25 h, P = 0.038), especially for open gastrectomy(76.53 ± 14.29 vs 87.23 ± 20.75 h, P = 0.048). Bowel sounds on day 2 in the TEA group were significantly greater than in the control group(2.30 ± 2.61/min vs 1.05 ± 1.26/min, P = 0.017). Time to nasogastric tube removal in the TEA group was earlier than in the control group(4.22 ± 1.01 vs 4.97 ± 1.67 d, P = 0.049), as well as the time to liquid diet(5.0 ± 1.34 vs 5.83 ± 2.10 d, P = 0.039). Hospital stay in the TEA group was significantly shorter than in the control group(8.06 ± 1.75 vs 9.40 ± 3.09 d, P = 0.041). No significant differences in postoperative symptom assessment and complications were found between the groups. There were no severe adverse events related to TEA.CONCLUSION TEA accelerated bowel movements and alleviated POI after open gastrectomy and shortened hospital stay.展开更多
A 35-year-old woman who had one delivery by cesarean section got pregnant again. Color Doppler flow imaging and Magnetic resonance imaging （MRI） showed a cesarean scar pregnancy （CSP）. Uterine arterial embolizati...A 35-year-old woman who had one delivery by cesarean section got pregnant again. Color Doppler flow imaging and Magnetic resonance imaging （MRI） showed a cesarean scar pregnancy （CSP）. Uterine arterial embolization （UAE） and curettage was performed successfully to terminate the pregnancy. Six months after the curettage, the patient＇s menstrual flow was reduced to one non-drenched sanitary pad per day for only 1-2 d, every 30 d. The patient underwent hysterosalpingography （HSG）, which suggested the presence of a filling-defect of the left uterine cavity, with obstructed bilateral Fallopian tubes. The patient subsequently underwent lysis of adhesions by hysteroscopy plus an exploratory laparoscopy, under general anesthesia. Her men- struation gradually increased to 5-7 d every 30 d. As the patient did not become pregnant during the first year after surgery, she underwent in vitro fertilization （IVF） treatment and a repeat ultrasound showed a somewhat thin endometrial line. At last, the patient got pregnant and gave birth to a live baby by IVF.展开更多
基金We thank Drs Chenbing Guan and Kui Cui （Institute of Neuroscience, Shanghai Institute for Biological Science, China） for technical support in setting up the single-cell migration assay, and Dr Qian Hu （Institute of Neuroscience, Shanghai Institute for Biological Science, China） for microscopic imaging. This study was supported by the National Key Basic Research Program （2006CB500702）, Ministry of Science and Technology of China （2007CB947100）, National Natural Science Foundation of China （30530240 and 30770657）, Program for Changdiang Scholars and Innovative Research Teams in Universities （IRT0528）, and Shanghai Metropolitan Fund for Research and Development （07DJ14005）.
基金Supported by Zhejiang Provincial Chinese Medicine Scientific Research Fund,No.2017ZA085
文摘AIM To investigate the efficacy and safety of transcutaneouselectroacupuncture(TEA) to alleviate postoperative ileus(POI) after gastrectomy.METHODS From April 2014 to February 2017, 63 gastric cancer patients were recruited from the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China. After gastrectomy, the patients were randomly allocated to the TEA(n = 33) or control(n = 30) group. The patients in the TEA group received 1 h TEA on Neiguan(ST36) and Zusanli(PC6) twice daily in the morning and afternoon until they passed flatus. The main outcomes were hours to the first flatus or bowel movement, time to nasogastric tube removal, time to liquid and semi-liquid diet, and hospital stay. The secondary outcomes included postoperative symptom assessment and complications.RESULTS Time to first flatus in the TEA group was significantly shorter than in the control group(73.19 ± 15.61 vs 82.82 ± 20.25 h, P = 0.038), especially for open gastrectomy(76.53 ± 14.29 vs 87.23 ± 20.75 h, P = 0.048). Bowel sounds on day 2 in the TEA group were significantly greater than in the control group(2.30 ± 2.61/min vs 1.05 ± 1.26/min, P = 0.017). Time to nasogastric tube removal in the TEA group was earlier than in the control group(4.22 ± 1.01 vs 4.97 ± 1.67 d, P = 0.049), as well as the time to liquid diet(5.0 ± 1.34 vs 5.83 ± 2.10 d, P = 0.039). Hospital stay in the TEA group was significantly shorter than in the control group(8.06 ± 1.75 vs 9.40 ± 3.09 d, P = 0.041). No significant differences in postoperative symptom assessment and complications were found between the groups. There were no severe adverse events related to TEA.CONCLUSION TEA accelerated bowel movements and alleviated POI after open gastrectomy and shortened hospital stay.
文摘A 35-year-old woman who had one delivery by cesarean section got pregnant again. Color Doppler flow imaging and Magnetic resonance imaging （MRI） showed a cesarean scar pregnancy （CSP）. Uterine arterial embolization （UAE） and curettage was performed successfully to terminate the pregnancy. Six months after the curettage, the patient＇s menstrual flow was reduced to one non-drenched sanitary pad per day for only 1-2 d, every 30 d. The patient underwent hysterosalpingography （HSG）, which suggested the presence of a filling-defect of the left uterine cavity, with obstructed bilateral Fallopian tubes. The patient subsequently underwent lysis of adhesions by hysteroscopy plus an exploratory laparoscopy, under general anesthesia. Her men- struation gradually increased to 5-7 d every 30 d. As the patient did not become pregnant during the first year after surgery, she underwent in vitro fertilization （IVF） treatment and a repeat ultrasound showed a somewhat thin endometrial line. At last, the patient got pregnant and gave birth to a live baby by IVF.
