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Lipase-catalyzed Regioselective Synthesis of Vinyl Ester Derivatives of Thiamphenicol: Novel Thiamphenicol Monomers for Preparation of Macromolecular Antibiotic
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作者 YuZhenSHI zhichunchen +2 位作者 NaWANG QiWU XianFuLIN 《Chinese Chemical Letters》 SCIE CAS CSCD 2005年第1期45-48,共4页
Three polymerizable vinyl thiamphenicol esters with different acyl donor carbon chain length (C4, C6, C10) were regioselectivly synthesized by Lipozyme? (immobilized from mucor miehei) in acetone at 50 oC for 12 h t... Three polymerizable vinyl thiamphenicol esters with different acyl donor carbon chain length (C4, C6, C10) were regioselectivly synthesized by Lipozyme? (immobilized from mucor miehei) in acetone at 50 oC for 12 h to give 73%, 81%, 63% yield, respectively. The products were valuable monomers for preparation of macromolecular antibiotic. 展开更多
关键词 THIAMPHENICOL vinyl ester TRANSESTERIFICATION regioselectivity monomer.
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