The Influence Factors of Collective Intelligence Emergence in Knowledge Communities Based on Social Network Analysis

The advent of the age of Information shifts the environment we live in from off-line to on-line. The prospect of Collective Intelligence (CI) is promising. Based on this background, the aim of this paper is to discover the emergence mechanism and influence factors of CI in knowledge communities using the method of quantitative and qualitative analysis. On the basis of the previous research work, our model theorizes that the two dimensions of social network (i.e., interactive network structure and participant’s characteristics) affect two references of effectiveness (i.e. group knowledge production and participation of group decision). And this hypothetical model is validated with simulation data from “Zhihu” community. Our model has been useful since it offers some inspirations and directions to promote the level of CI in knowledge communities.

Preparation and Characterization of Sulfated Cellulose Nanocrystalline and its Composite Membrane for Removal of Tetracycline Hydrochloride in Water

The removal of antibiotic pollutants remaining in the environmental media has been a big challenge nowadays.Herein,we report a facile and green approach to fabricate an eco-friendly composite membrane without addition of any toxic polymers or chemical cross-linking agents to effectively remove the tetracycline hydrochloride in Water.Firstly,the sulfated cellulose nanocrystalline(CNC) was obtained via hydrolysis of sulfuric acid by using microcrystalline cellulose(MCC) as raw material under ultrasonic condition.The as-prepared CNC has a nanowhisker dimension with 200.2 ± 110.2 nm in length,15.7 ± 9.3 nm in width,and 7.2 ± 3.1 nm in height.The obtained CNC is cellulose type I as determined by X-ray diffraction(XRD),while its crystallinity index(Crl) can reach 82.3%.Then,the composite membrane derived from the obtained CNC and commercial mixed cellulose ester(MCE)membrane was facilely prepared through vacuum dewatering process,which is applied to remove tetracycline hydrochloride(Th) in solution.The results showed that the removal efficiency of Th through the neat MCE was only28 ± 4%,while it could be improved to 58 ± 5% and 89 11%,respectively,by filtering through composite membranes with different contents of CNC deposition.Such effect is derived from the combine factors based on both steric hindrance(sieving) and electrostatic interaction(Donnan) effect of the composite membranes.The development of related CNC materials and composite fabrication processes is in favor of cost-effective and "green"polymer composites for the remediation of increasing antibiotic pollution and the purification of contaminated water nowadays.

An AuNPs/Mesoporous NiO/Nickel Foam Nanocomposite as a Miniaturized Electrode for Heavy Metal Detection in Groundwater

Heavy metals,notably Pb2+and Cu^(2+),are some of the most persistent contaminants found in groundwater.Frequent monitoring of these metals,which relies on efficient,sensitive,cost-effective,and reliable methods,is a necessity.We present a nanocomposite-based miniaturized electrode for the concurrent measurement of Pb2+and Cu^(2+)by exploiting the electroanalytical technique of square wave voltammetry.We also propose a facile in situ hydrothermal calcination method to directly grow binder-free mesoporous Ni O on a three-dimensional nickel foam,which is then electrochemically seeded with gold nanoparticles(Au NPs).The meticulous design of a low-barrier Ohmic contact between mesoporous Ni O and Au NPs facilitates target-mediated nanochannel-confined electron transfer within mesoporous Ni O.As a result,the heavy metals Pb2+(0.020 mg.L^(-1)detection limit;2.0–16.0 mg.L^(-1)detection range)and Cu^(2+)(0.013 mg.L^(-1)detection limit;0.4–12.8 mg.L^(-1)detection range)can be detected simultaneously with high precision.Furthermore,other heavy metal ions and common interfering ions found in groundwater showed negligible impacts on the electrode’s performance,and the recovery rate of groundwater samples varied between 96.3%±2.1%and 109.4%±0.6%.The compactness,flexible shape,low power consumption,and ability to remotely operate our electrode pave the way for onsite detection of heavy metals in groundwater,thereby demonstrating the potential to revolutionize the field of environmental monitoring.

Prognostic and clinical value of circPRKCI expression in diverse human cancers

Background:Highly expressed in various human cancers,circular RNA Protein Kinase C Iota(circPRKCI)has been reported to play an important role in cancer development and progression.Herein,we sought to reveal the prognostic and clinical value of circPRKCI expression in diverse human cancers.Methods:We searched the Pubmed,Web of Science,and the Cochrane Library databases from inception until May 16,2021.The relationship between circPRKCI expression and cancer patients’survival,including overall survival(OS)and disease-free survival(DFS),was assessed by pooled hazard ratios(HR)with corresponding 95%confidence interval(CI).The correlation between circPRKCI expression and clinical outcomes was evaluated using odds ratios(OR)with corresponding 95%CI.The data were analyzed by STATA software(version 12.0)or Review Manager(RevMan 5.3).Results:A total of 15 studies with 1109 patients were incorporated into our meta-analysis.The results demonstrated that high circPRKCI expression was significantly related to poor OS(HR=1.96,95%CI:1.61,2.39,P<0.001)when compared with low circPRKCI expression in diverse human cancers.However,elevated circPRKCI expression was not associated with DFS(HR=1.34,95%CI:0.93,1.95,P=0.121).Furthermore,the patient with a higher circPRKCI expression was prone to have a larger tumor size,advanced clinical stage,and lymph node metastasis,but it was not significantly correlated with age,gender,and distant metastasis.Conclusion:Elevated circPRKCI expression was correlated with worse OS and unfavorable clinical features,suggesting a novel prognostic and predictive role of circPRKCI in diverse human cancers.

qRgls1.06, a major QTL conferring resistance to gray leaf spot disease in maize

Gray leaf spot(GLS)caused by Cercospora zeae-maydis and C.zeina is an extremely devastating leaf disease that limits maize production annually.The use of GLS-resistant maize hybrids is the most cost-effective approach for reducing losses.Resistance to GLS is quantitatively inherited in maize(Zea mays L.)and further sources of resistance remain to be analyzed.Here,we detected qRgls1.06,a major quantitative trait locus for GLS resistance in bin 1.06 that explained approximately 55%of the phenotype variance.Fine mapping over 2 consecutive years localized qRgls1.06 to a 2.38-Mb region.Homozygous qRgls1.06^(WGR/WGR) plants in DZ01 background displayed higher GLS resistance and 100-grain weight than DZ01 plants.The GLS responses of several susceptible elite inbred lines were improved by the introduction of qRgls1.06 by marker-assisted backcrossing.Our findings extend the understanding of the genetic basis of resistance to GLS and provide a set of resistant germplasm for genetic improvement of resistance to GLS in maize.

High‑Performance Flexible Microneedle Array as a Low‑Impedance Surface Biopotential Dry Electrode for Wearable Electrophysiological Recording and Polysomnography

Microneedle array(MNA)electrodes are an effective solution to achieve high-quality surface biopotential recording without the coordination of conductive gel and are thus very suitable for long-term wearable applications.Existing schemes are limited by flexibility,biosafety,and manufacturing costs,which create large barriers for wider applications.Here,we present a novel flexible MNA electrode that can simultaneously achieve flexibility of the substrate to fit a curved body surface,robustness of microneedles to penetrate the skin without fracture,and a simplified process to allow mass production.The compatibility with wearable wireless systems and the short preparation time of the electrodes significantly improves the comfort and convenience of electrophysiological recording.The normalized electrode–skin contact impedance reaches 0.98 kΩcm^(2)at 1 kHz and 1.50 kΩcm^(2)at 10 Hz,a record low value compared to previous reports and approximately 1/250 of the standard electrodes.The morphology,biosafety,and electrical/mechanical properties are fully characterized,and wearable recordings with a high signal-to-noise ratio and low motion artifacts are realized.The first reported clinical study of microneedle electrodes for surface electrophysiological monitoring was conducted in tens of healthy and sleep-disordered subjects with 44 nights of recording(over 8 h per night),providing substantial evidence that the electrodes can be leveraged to substitute for clinical standard electrodes.

Breaking Key Obstacles on Developing Circular Agriculture and Promoting Agricultural and Pasture Resources Benefit

The present situation,problems and constraints of the circular agriculture development in Hebei Province are systematically analyzed,the subject modes suitable for the development of circular agriculture and the value-added potential are described,and finally some proposals are put forward.

A DFT study on the interaction of Co with an anatase TiO_2 (001)-(1×4) surface

The substitution/adsorption structures of Co on an anatase TiO2 （001）-（1 × 4） surface are investigated using the DFT/local density approximation （LDA） method. Theoretical calculation shows that the Co ion prefers to be adsorbed on the surface of anatase TiO2. The density of states （DOS） analysis finds that the Co 3d is located mainly in the energy gap region. The Co 3d partial density of states （PDOS） indicates that there is a substantial degree of hybridization between O 2s and Co 3d in valence band （VB） regions in the substitution models. The conclusion is that the mode of substitution is more active when the catalyst is a higher-energy surface.

Research Progress of HPV L1 Capsid Protein in Prediction of Cervical Lesions

Cervical cancer is one of the most common malignant gynecological tumors and has the second highest incidence of all malignancies in females.Chronic and persistent infection with High Risk Human Papillomavirus(HR-HPV)is the main cause of cervical cancer.There is a distinct lack of methodology by which to determine whether cervical epithelial dysplasia is cancerous following HPV infection.HPV L1 capsid protein is a major structural protein of human papillomavirus(HPV),and it is the main target of the local cellular immune response aiming to combat human papillomavirus after HPV infection within cervical cells.Greater understanding of HPV L1 capsid protein and its association with cervical cytology,histopathology,patient age and human papillomavirus viral load has the potential to contribute toward improved the diagnosis and management of cervical cancer,providing useful information for gynecological clinicians in the hope of improving patient treatment and quality of life.This article reviews the predictive utility of HPV L1 capsid protein for cervical lesions.

Calibration and Experimental Research of a Multiple-wavelength Flame Temperature Instrumentation System

This paper presents a study on a novel instrumentation system for the measurement of temperature distribution of combustion flames. This system operates upon the three-color principle combining advanced optical sensing and digital image processing techniques. It comprises an endoscope, a light splitter assembly, a CCD camera, a frame-grabber and associated software. This system was calibrated using a blackbody furnace as standard temperature source. The relationship between flame temperatures and grey-level of the images was established through image processing and function correlation. Experimental results obtained on a gas-fired combustion rig provide flame images and temperature distributions on three different wavelengths. Based on the flame temperature distribution the combustion conditions can be analyzed. Experimental results also reveal that this system is capable of online measurement of temperature distribution in a combustion zone. This system can potentially be applied to many areas such as power generation, metallurgy, chemical engineering. It is also a powerful tool for improving the control of combustion process.

Three new lignan glucosides from the roots of Scutellaria baicalensis

Three new lignan glucosides, baicalensinosides A–C(1–3), were isolated from the roots of Scutellaria baicalensis. The structural elucidation was achieved by in-depth spectroscopic examinations and qualitative chemical test. Structurally, these compounds belong to the 3,4-dibenzyltetrahydrofurantype lignan glycoside with a mono-hydroxyl substitution at the 70-position of benzylidene group on the numbering system of lignans being one of their shared critical features. The anti-osteoporotic activity of the isolated compounds was assessed in an in vitro osteoprotegerin(OPG) transcriptional activity assay using dual luciferase reporter detection. At 10 μmol/L, compounds 1–3 increased the relative activating ratio of OPG transcription to 1.83, 0.84 and 0.98 times that of the control group, respectively.

CB1R-stabilized NLRP3 inflammasome drives antipsychotics cardiotoxicity

Long-term use of antipsychotics is a common cause of myocardial injury and even sudden cardiac deaths that often lead to drug withdrawn or discontinuation.Mechanisms underlying antipsychotics cardiotoxicity remain largely unknown.Herein we performed RNA sequencing and found that NLRP3 inflammasome-mediated pyroptosis contributed predominantly to multiple antipsychotics cardiotoxicity.Pyroptosis-based small-molecule compound screen identified cannabinoid receptor 1(CB1R)as an upstream regulator of the NLRP3 inflammasome.Mechanistically,antipsychotics competitively bond to the CB1R and led to CB1R translocation to the cytoplasm,where CB1R directly interacted with NLRP3 inflammasome via amino acid residues 177–209,rendering stabilization of the inflammasome.Knockout of Cb1r significantly alleviated antipsychotic-induced cardiomyocyte pyroptosis and cardiotoxicity.Multi-organ-based investigation revealed no additional toxicity of newer CB1R antagonists.In authentic human cases,the expression of CB1R and NLRP3 inflammasome positively correlated with antipsychotics-induced cardiotoxicity.These results suggest that CB1R is a potent regulator of the NLRP3 inflammsome-mediated pyroptosis and smallmolecule inhibitors targeting the CB1R/NLRP3 signaling represent attractive approaches to rescue cardiac side effects of antipsychotics.

Empirical formula for β^--decay half-lives of r-process nuclei

Experimental data ofβ--decay half-lives of nuclei with atomic number between 20 and 190 are investigated.A systematic formula has been proposed to calculateβ^--decay half-lives of neutron-rich nuclei,with a particular consideration on shell and pair effects,the decay energy Q as well as the nucleon numbers(Z,N).Although the formula has relatively few parameters,it reproduces the experimentalβ^--decay half-lives of neutron-rich nuclei very well.The predicted half-lives for the r-process relevant nuclei obtained with the current formula serve as reliable input in the r-process model calculations.

Tunable seesaw-like 3D capacitive sensor for force and acceleration sensing

To address the resource-competing issue between high sensitivity and wide working range for a stand-alone sensor,development of capacitive sensors with an adjustable gap between two electrodes has been of growing interest.While several approaches have been developed to fabricate tunable capacitive sensors,it remains challenging to achieve,simultaneously,a broad range of tunable sensitivity and working range in a single device.In this work,a 3D capacitive sensor with a seesaw-like shape is designed and fabricated by the controlled compressive buckling assembly,which leverages the mechanically tunable configuration to achieve high-precision force sensing(resolution~5.22 nN)and unprecedented adjustment range(by~33 times)of sensitivity.The mechanical tests under different loading conditions demonstrate the stability and reliability of capacitive sensors.Incorporation of an asymmetric seesaw-like structure design in the capacitive sensor allows the acceleration measurement with a tunable sensitivity.These results suggest simple and low-cost routes to high-performance,tunable 3D capacitive sensors,with diverse potential applications in wearable electronics and biomedical devices.

认知神经美学视域下的“审美表象”——康德《判断力批判》导论·七细读

康德“第三批判”的关键词是主观的“埃斯特惕卡判断”,实即“内隐感性判断”或内隐认知;与埃斯特惕卡判断结成合目的性关系的是客观对象的埃斯特惕卡表象。这一表象不是实有的、结构性的、可凭感官加以直观的,而是假设的、虚拟的,仅相对于埃斯特惕卡判断力才存在。二者之能结成合目的性关系,要凭借埃斯特惕卡判断力所具有的特殊认识能力,即“想象力与知性的一致”。这种认识能力实即知性概念框架下具有想象力功能的内在直观力,亦即内隐认知力。当埃斯特惕卡判断凭借这种认识能力与埃斯特惕卡表象结成合目的性关系时,愉快情感(美感)就形成了。这时,具有埃斯特惕卡表象并引发愉快的对象事物就被称为“美的”(不是“美”)。

First record of Liposcelis entomophila(Enderlein)(Psocodea: Liposcelididae) from Sri Lanka based on morphological and molecular data

The booklice genus,Liposcelis(Psocodea:Liposcelididae),owns some stored product pests and have economic importance.In this study,6 booklice specimens from Sri Lanka were collected and identified based on morphological and molecular data.According to the morphological and phylogenetic analyses,the samples were identified as Liposcelis entomophila.The mitochondrial gene cytochrome c oxidase I(COI)and second internal transcribed spacer(ITS2)were sequenced for phylogenetic work.The phylogenetic trees show that the samples assemble with L.entomophila together and could be distinguished with other Liposcelis spp.apparently.The genus Liposcelis and the species L.entomophila are firstly reported in Sri Lanka.

A simple vacuum sample chamber for small-angle X-ray scattering at Beijing synchrotron radiation facility

Objective A vacuum sample chamber for SAXS measurement of solutions was developed to improve the signal-to-noise ratio of the instrument at Beijing Synchrotron Radiation Facility(BSRF).Methods We developed a vacuum sample chamber which could be connected to the upstream and the downstream vacuum tubes by bellows.Horizontal and vertical linear slides were mounted in the vacuum chamber to adjust the sample position by 35 mm in the horizontal and vertical directions to align the sample in the light path.The liquid sample holder of the chamber was sealed with polyimide film by squeezing instead of gluing to avoid the potential influence of sealant on the solution.Results The chamber had been used for SAXS measurements of water and bovine serum albumin solution at BSRF.The results showed that the background scattering intensity in air was much higher than that in vacuum,especially in the smallangle area near the beamstop.When the q value is 0.142 nm−1,1.01 nm−1 and 1.25 nm−1,the background scattering intensity in air is 45,6.8 and 4.6 times of that in vacuum,respectively.And the background-subtracted scattering curves of bovine serum albumin solution(10 mg/ml)in air and vacuum differ in intensity by a factor of about 2.When the q value is 2 nm−1,the signal-to-noise ratios of scattering intensity of BSA in air and vacuum are 0.79 and 8.51,respectively.Conclusion We designed a simple vacuum sample chamber to be used on the SAXS instrument at 1W2A station of BSRF.The scattering of the background and protein solution in air and vacuum was tested and compared,and the signal-to-noise ratio was clearly improved.

锦屏深地核天体物理实验(JUNA)的首个结果:^(25)Mg(p,γ)^(26)Al反应92 keV共振的精确测量

银河系星际介质中的^(26)Al衰变发射的1.809 MeVγ射线是γ天文学的主要观测对象之一,是银河系中正在进行核合成的关键证据,也为核合成理论与天文观测进行比较提供一个重要基准.在大质量恒星氢燃烧中,^(26)Al主要通过^(25)Mg(p,γ)^(26)Al反应产生,因此该反应在1.809 MeVγ射线研究中起着重要的作用.在天体环境温度为0.1 GK左右时,^(25)Mg(p,γ)^(26)Al天体物理反应率主要由92 keV共振俘获过程决定.作为在中国锦屏地下实验室(CJPL)中锦屏核天体物理实验(JUNA)装置上进行的首个实验,本工作对^(25)Mg(p,γ)^(26)Al反应的92 keV共振进行了精确的实验测量,得到了该共振的共振强度为ωγ=(3.80.3)10^(-10) eV,基态分支比为f0=0.660.04.与之前的工作相比,本工作大大提高了92 keV共振数据的精度.基于测量的92 keV共振参数和以前的间接测量结果,得到了精度最高的^(25)Mg(p,γ)^(26)Al天体物理反应率.结果表明,在0.1 GK左右时,新的反应率比REACLIB数据库中采用的反应率大2.4倍,这将导致^(26)Al和宇宙1.809 MeVγ射线的产额提高.同时,新反应率也将对理解太阳系的形成、球状星团的元素丰度反相关等问题提供重要的数据支撑.

^(22)Ne(α,n)^(25)Mg反应:大质量恒星中的关键中子源

宇宙从铁到铀的超铁元素起源是核天体物理领域一个重要的前沿方向,被认为是21世纪“物理学的11个未解之谜”之一,有望孕育出重大科学发现中子俘获反应可以克服库仑势垒,是生成宇宙中超铁元素的关键途径.自由中子的平均寿命只有约15min,因此,中子的来源对理解超铁元素起源是一个热点课题.本文评述了超铁元素起源、大质量恒星中的关键中子源^(22)Ne(α,n)^(25)Mg反应的研究意义、中子源最新研究进展和未来研究计划,特别是深地直接测量实验计划.