地铁车辆基地全框支剪力墙结构层间位移角限值讨论

车辆基地全框支剪力墙结构是新型的结构形式,在工程实践中有对底部框架侧向刚度控制得过于严格的现象,相关设计标准中要求底部框架层间位移角不宜大于1/2 000。讨论了控制上部剪力墙结构层间位移角的依据、目的和计算中存在的问题,比较了底盘平面大小对底部框架层间位移角的影响。建议车辆基地全框支剪力墙结构上部剪力墙的层间位移角限值按广东省标准《高层建筑混凝土结构技术规程》(DBJ/T 15-92—2021)取为多遇地震作用下1/450;在保证上部剪力墙先于底部框支框架屈服的前提下,大幅度放松底部框架层间位移角限值及非两区八类建筑全框支剪力墙减隔震结构层间位移角限值,也取为多遇地震作用下1/450。实现合理的屈服机制尤为重要。

The Role of Pharmacists in Perioperative Antibiotic Application in a Hospital of Traditional Chinese Medicine (TCM)

Objective: To determine adherence to Chinese guidelines for perioperative antibiotic use in our hospital of TCM and discuss the role of pharmacists on antibiotic management. Methods: 2844 operative cases between May 2011 and December 2011 in our hospital were investigated by pharmacists and relative data were collected, including demographic data, type of surgery, wound classification (clean and clean contaminated) and parameters of antibiotic application (antibiotic choice, route, dose, time of first dose, time of operative re-dosing and duration of prophylaxis). The rationality of antibiotic administration in these cases was respectively evaluated based on Chinese guidelines for perioperative antibiotic use. Results: After intervention of pharmacists, perioperative antibiotic application in our hospital was obviously improved from May to December of 2011: the rates of antibiotic application in operative cases and antibiotic prophylaxis in clean operation were both decreased. However, there was no significant improvement for the rate of rationality. In detail, TCM surgery was well compliant with the guidelines: the rate of antibiotic application was less than 30%, regimen of antibiotic prophylaxis and therapy was reasonable;in the breast ward, antibiotic application was improved after pharmacists’ intervention: the rate of antibiotic prophylaxis in clean operation significantly decreased from 100% to 30%;however, in the anorectal ward, some troubles were resolved while other new problems came out;in other ward such as general surgery and orthopedics, old problems still existed. Conclusions: Protocol violations were frequent to perioperative antibiotic application in our hospital due to considerable over prescription. Intervention was effective but not enough. Further educational strategies are essential for reducing costs and antibiotic resistance rates.

Investigation of La_(9.33)Si_6O_(26) Oxygen Ionic Conductor

La9.33Si6O26 氧离子导体被稳固的州的 reactionmethod.Its 综合结构被单个水晶的 X 光检查衍射分析在结果显示出的 roomtemperature.The 决定那 La9.33Si6O26 氧化物让磷灰石组织，空间 groupP6_3/m.AC 阻抗大小显示了在氮的氧化物 sintered 在空中比那些 sintered 有高得多的电导率。传导性上的谷物边界的效果被讨论。

A functionalized separator enables dendrite-free Zn anode via metal-polydopamine coordination chemistry

Designing a multifunctional separator with abundant ion migration paths is crucial for tuning the ion transport in rocking-chair-type batteries.Herein,a polydopamine-functionalized PVDF(PVDF@PDA)nanofibrous membrane is designed to serve as a separator for aqueous zinc-ion batteries(AZIBs).The functional groups(OH and NH)in PDA facilitate the formation of Zn O and Zn N coordination bonds with Zn ions,homogenizing the Zn-ion flux and thus enabling dendrite-free Zn deposition.Moreover,the PVDF@PDA separator effectively inhibits the shuttling of V-species through the formation of V-O coordination bonds.As a result,the Zn/NH_(4)V_(4)O_(10) battery with the PVDF@PDA separator exhibits enhanced cycling stability(92.3%after 1000 cycles at 5 A g^(-1))and rate capability compared to that using a glass fiber separator.This work provides a new avenue to design functionalized separators for high-performance AZIBs.

近代北京第一座无线广播电台

1923年,哈尔滨、上海开始出现无线广播电台,兴办无线广播电台的潮流很快扩展到天津、沈阳等地。1927年9月1日,北京无线广播电台[1]开始正式播音,这是近代北京第一座无线广播电台。无线广播电台的出现,象征着北京开始融入20世纪20年代兴起的世界无线广播潮流。

The Pharmacodynamic Study of Qin Bing Eye Drop on Photokeratoconjunctivitis

Background: Qin Bing eye drop is prepared with cortex fraxini and borneol. It has been commonly used to relieve the symptoms of photokeratoconjunctivitis (PKC), chronic conjunctivitis and keratitis for more than forty years. However, the origins of cortex fraxini are various, which may result in the unstable quality. Methods: The animal model of PKC was established using rabbit’s eyes exposure to Ultraviolet (UV);levofloxaxin drop, normal saline, Qin Bing eye drops made of herbs from Hebei province and Shanxi province were respectively instilled to both eyes of rabbits;the symptoms of rabbits’ eyes were observed at different time points and scores based on weights were recorded;the recovery rates of different groups were evaluated. Results: The scores of both eyes for all rabbits were above 9 points, indicating animal models for PKC were successful;the average recovery rates of therapeutic groups, including Qin Bing eye drop groups, were higher than untreated group at different time points;the slopes of recovery rate in Qin Bing eye drop (Hebei) were above Shanxi. Conclusion: PKD animal model can be established successfully;Qin Bing eye drop groups promoted the symptoms of PKD recovering quicker than untreated group. Furthermore, Qin Bing eye drop made of herbs from province Hebei had better effects than Shanxi, which was consistent with chemical results. This indicated that chemical constituents of herbs were able to reflect the effects to a certain extent.

Single-cell RNA-seq Revealed that Altered Tumor Infiltrating Lymphocytes in Cirrhotic Liver Indicate Development of Hepatocellular Carcinoma

Background and Aims:Cirrhosis is the precursor lesion for most hepatocellular carcinoma(HCC)cases.However,no biomarker effectively predicted HCC initiation before diagnosis by imaging.We aimed to investigate the hallmarks of immune microenvironments in healthy,cirrhotic livers and HCC tumor tissues and to identify immune biomarkers of cirrhosis-HCC transition.Methods:Expression matrices of singlecell RNA sequencing studies were downloaded and integrated with Seurat package vignettes.Clustering was performed to analyze the immune cell compositions of different sample types.Results:The cirrhotic liver and HCC tumors had distinct immune microenvironments,but the immune landscape of cirrhotic livers was not markedly modified compared with healthy livers.Two subsets of B cells and three subsets of T cells were identified in the samples.Among the T cells,naïve T cells were more prominent in the cirrhotic and healthy liver samples than in the HCC samples.In contrast,the neutrophil count was lower in cirrhotic livers.Two macrophage clusters were identified,one that actively interacted with T cells and B cells and was enriched in cirrhotic blood compared with HCC blood samples.Conclusions:Decreased naïve T cell infiltration and increased neutrophil infiltration in the liver may indicate the development of HCC in cirrhotic patients.Alterations in blood-resident immune cells may also be a sign of HCC development in cirrhotic patients.The dynamics of the immune cell subsets may serve as novel biomarkers to predict the transition from cirrhosis to HCC.

Promoting the application of pediatric radiomics via an integrated medical engineering approach

Radiomics is widely used in adult tumors but has been rarely applied to the field of pediatrics.Promoting the application of radiomics in pediatric diseases,especially in the early diagnosis and stratified treatment of tumors,is of great value to the realization of the WHO 2030“Global Initiative for Childhood Cancer.”This paper discusses the general characteristics of radiomics,the particularity of its application to pediatric diseases,and the current status and prospects of pediatric radiomics.Radiomics is a data-driven science,and the combination of medicine and engineering plays a decisive role in improving data quality,data diversity,and sample size.Compared with adult radiomics,pediatric radiomics is significantly different in data type,disease spectrum,disease staging,and progression.Some progress has been made in the identification,classification,stratifica-tion,survival prediction,and prognosis of tumor diseases.In the future,big data applications from multiple centers and cross-talent training should be strengthened to improve the benefits for clinical workers and children.

面向超可靠低时延通信的有限块长MIMO传输理论与技术

超可靠低时延通信是5G及未来6G无线通信系统的重要组成部分.针对该类通信场景,如何从MIMO传输的角度实现时延和可靠性的最佳折中,是近年来备受关注的一项研究课题.由于现有基于长包假设的经典MIMO传输体系难以满足系统对于时延和可靠性的严苛要求,亟需研究更具挑战性的有限块长MIMO传输理论和技术.本文围绕有限块长MIMO信息论、发射机以及接收机设计的已有研究工作进行全面总结,并重点介绍二维空时信道编码以及MIMO一体化接收机等新型技术,为显著提升超可靠低时延通信的性能提供指导.另外,本文简要介绍了作者所在课题组搭建的MIMO超可靠低时延试验验证平台,为后续相关理论与算法的验证奠定试验基础.

Electrochemical performances of NiO/Ni2N nanocomposite thin film as anode material for lithium ion batteries

Despite the high specific capacities,the practical application of transition metal oxides as the lithium ion battery(LIB)anode is hindered by their low cycling stability,severe polarization,low initial coulombic efficiency,etc.Here,we report the synthesis of the NiO/Ni2N nanocomposite thin film by reactive magnetron sputtering with a Ni metal target in an atmosphere of 1 vol.% O2 and 99 vol.%N2.The existence of homogeneously dispersed nano Ni2N phase not only improves charge transfer kinetics,but also contributes to the one-off formation of a stable solid electrolyte interphase(SEI).In comparison with the NiO electrode,the NiO/Ni2N electrode exhibits significantly enhanced cycling stability with retention rate of 98.8%(85.6%for the NiO electrode)after 50 cycles,initial coulombic efficiency of 76.6%(65.0%for the NiO electrode)and rate capability with 515.3 mA·h·g^−1(340.1 mA·h·g^−1 for the NiO electrode)at 1.6 A·g^−1.

High lithium storage performance of Ni_(0.5)Fe_(0.5)O_(1-x)Nx thin film with Nio-type crystal structure

The large voltage hysteresis of the NiO anode,which owes much to the intermediate product Li_(2)NiO_(2),is one of the main obstacles to its practical application in lithium-ion batteries.In this work,we show that the incorporation of Fe-and N-ions in the Nio lattice can suppress the formation of intermediate product Li_(2)NiO_(2)and thus greatly reduces the voltage hysteresis of the Nioanode from~1.2 to~0.9 V.In comparison with the pure Nio electrode,the Nio.5Feo.5O1-xNx anode exhibits significantly enhanced reversible specific capacity(959 mAh·g^(-1)at 0.3 A·g^(-1)),cycling stability(capacity retention of 96.1%at 100th cycle relative to the second cycle)and rate capability(442 at 10 A·g^(-1)).These results provide a practical method to enhance the lithium storage performance of the Nio anode and more importantly a new solution to the large voltage hysteresis of conversion-type anodes.

Li-ion storage performance and electrochemically induced phase evolution of layer-structured Li[Li0.2Mn0.54Ni0.13Co0.13]02 cathode material

Li-rich Li[Li0.2Mn0.54Ni0.13Co0.13]02（LMNC） powders were synthesized by a gel-combustion method. The related microstructure, electrochemical performance and electrochemically induced phase evolution were characterized. The 900℃ calcined powders have a hexagonal layered structure with high ordered degree and low cationic mixing level. The calcined materials as cathode electrode for Li-ion battery deliver the high electrochemical properties with an initial discharge capacity of 243.5 mA. h. g-1 at 25 mA.g-1 and 249.2 mA-h.g-1 even after 50 cycles. The electrochemically induced phase evolution investigated by a transmission electron microscopy indicates that Li＋ ions deintercalated first from the LiMO2 （M = Mn, Co, Ni） component and then from Li2MnO3 component in the LMNC during the charge process, while Li＋ ions intercalated into Li1-xMO2 component followed by into MnO2 component during the discharge process.

Synthesis and characterization of Zr_(0.85)Y_(0.15)O_(1.925)-La_(9.33)Si_(6)O_(26) composite electrolyte for application in SOFCs

Composite oxide ionic conductors consisting of Zr_(0.85)Y_(0.15)O_(1.925)(YSZ)and La_(9.33)Si_(6)O_(26)(LSO)have been synthesized by a modified coprecipitation method.X-ray diffraction,electron microscope,and complex impedance were adopted to investigate the phase component,microstructures,and conductivities,respectively.The results show that the average grain sizes of the composite powders and as-sintered pellets are less than 20 nm and 200 nm,respectively.The conductivity of the composite materials composed of 94 wt%YSZ and 6 wt%LSO is 0.215 S/cm at 700℃.The conductivity of the composite is three times higher than that of the polycrystalline YSZ and has two orders in magnitude higher than that of the polycrystalline LSO at 700℃.By analyzing the impedance spectra and modulus spectra,the grain-boundary effect on the conductivity improvement is investigated and the conductive mechanisms of the composite materials are discussed.

Electrical properties and thermal sensitivity of Ti/Y modified CuO-based ceramic thermistors

The Ti/Y modified CuO-based negative temperature coefficient （NTC） thermistors, Cu0.988-2yY0.008TiyO （TYCO; y-- 0.01, 0.015, 0.03, 0.05 and 0.07）, were synthesized through a wet-chemical method followed by a traditional ceramic sintering technology. The related phase component and electrical properties were investigated. XRD results show that the TYCO ceramics have a monoclinic structure as that of CuO crystal. The TYCO ceramics can be obtained at the sintering temperature 970℃-990℃, and display the typical NTC characteristic. The NTC thermal-sensitive constants of TYCO thermistors can be adjusted from 1112 to 3700 K by changing the amount of Ti in the TYCO ceramics. The analysis of complex impedance spectra revealed that both the bulk effect and grain boundary effect contribute to the electrical behavior and the NTC effect. Both the band conduction and electron-hopping models are proposed for the conduction mechanisms in the TYCO thermistors.