High Expression of the RECK Gene in Breast Cancer Cells is Related to Low Invasive Capacity

OBJECTIVE To investigate the expression of the RECK gene in human breast (cancer) cell lines, and to determine the relationship between RECK gene expression and the invasive capacity of the breast cancer cell lines. METHODS The invasive capacity of breast (cancer) cell lines including HBL-100, MCF-7 and MDA-MB-435S were determined by the Tran-swell method. The protein expression levels of RECK, MMP-2 and MMP-9 genes in these three cell lines were measured by immunocytochemical methods. The expressions of the RECK gene and protein level were measured by RT-PCR and Western blots in the cell lines respectively. RESULTS The order of the invasive capacity of the breast (cancer) cell lines was MDA-MB-435S, being the highest, and HBL-100, being the lowest. The invasive capacity difference between any two groups among the three groups was significant (P<0.01). The protein expression level of the RECK gene in the HBL-100 cell line was highest, and no expression was detected in MDA-MB-435S cells. Moreover, the expression of the RECK gene was negatively correlated with the expression of the MMP-2 and MMP-9 genes. The mRNA level of the RECK gene in HBL-100 cells was the highest, but no expression was found in the MDA-MB-435S cells (P<0.001). CONCLUSION There was a significant negative correlation between the expression level of the RECK gene and invasive capacity in vitro, and the RECK gene expression showed an inverse proportion to that of the MMP-2, MMP-9 genes.

基于光致变色荧光粉发光可逆调控和颜色对比的光存储和防伪应用

光致变色和光致发光是两种有趣的光学现象,它们在单一材料中的结合可以应用于多级防伪和光学记忆存储等器件.然而,在双光刺激下开发一种同时具有光致变色和光致发光的材料是一个挑战.本工作利用缺陷诱导色心的形成制备了光致变色SrWO_(4):Yb^(3+),Er^(3+),Bi^(3+)荧光粉,在254 nm紫外光和473 nm激光交替照射下,获得了从白色到暗黄色的可逆光致变色.SrWO_(4):Yb^(3+),Er^(3+),Bi^(3+)的光致变色效应引起了可逆光致发光调控.基于相应的颜色对比和发光强度变化,实现了SrWO_(4):Yb^(3+),Er^(3+),Bi^(3+)荧光粉的光存储和防伪应用.在实际应用中,柔性SrWO_(4):Yb^(3+),Er^(3+),Bi^(3+)薄膜作为一种很有前途的替代材料,既能满足多样化的要求又能提高安全性,有望促进光致变色发光调控的研究.

基于光致变色效应的BaMgSiO4:Bi3+陶瓷的发光性质调控及信息的可逆写入、擦除和读出研究（英文）

光存储技术与传统固态存储和磁存储相比有许多优点,如成本低、可重复性存储.因此,光存储的需求正在持续增长.本文研究了铋掺杂的硅酸镁钡陶瓷的光致变色及光致发光现象.在紫外线(254 nm)和532 nm激光交替辐照下,实现了陶瓷在灰色与粉红色之间的可逆转变.研究证实MgSiO4:Bi^3+陶瓷的可逆光致变色来源于基质中的氧空位陷阱对电子的俘获和释放.基于可逆光致变色效应在陶瓷表面制作不同颜色的图案,实现了光信号的双模式存储和擦除.同时,在光致变色过程中实现了光致发光的可逆调控;通过这种可逆的发光调控行为,实现存储信息的读出;此外,变色和漂白的程度与光照射时间有关,因此可实现多通路编码存储,有望提高光存储容量.

Reversible 3D optical data storage and information encryption in photo-modulated transparent glass medium

Transparent glass has been identified as a vital medium for three-dimensional(3D)optical information storage and multi-level encryption.However,it has remained a challenge for directly writing 3D patterning inside a transparent glass using semiconductor blue laser instead of high-cost femtosecond laser.Here,we demonstrate that rare earth ions doped transparent glass can be used as 3D optical information storage and data encryption medium based on their reversible transmittance and photoluminescence manipulation.The color of tungsten phosphate glass doped with rare earth ions change reversibly from light yellow to blue upon alternating 473 nm laser illumination and temperature stimulation,resulting in the reversible luminescence modulation.The information data could be repeatedly written and erased in arbitrary 3D space of transparent glass,not only showing the ability of the excellent reproducibility and storage capacity,but also opening opportunities in information security.The present work expands the application fields of luminescent glass,and it is conducive to develop a novel 3D data storage and information encryption media.

Intense single-band red upconversion emission in BiOCl:Er3+ layered semiconductor via co-doping Ho3+

Exploring a new tuning way to facilely realize single-band red emission in trivalent rare-earth ions(RE3+) doped upconversion(UC) materials is still desirable.In this work,the intense single-band red emission is achieved by co-doping only Ho3+in the BiOCl:Er3+ under 1550 nm excitation.In the BiOCl layered host,co-doping Ho3+can further enhance the red emission and simultaneously suppress the green emission of Er3+,and thus obviously improve the red-to-green(R/G) ratio.It is found that Ho3+does not se rve as ene rgy trapping through the 5 I6 state as in traditional UC materials but acts as ET bridge(4 S3/2,2 H11/2(Er3+)→5 F4,5 S2(Ho3+)→4 F9/2(Er3+)).The tuning mechanism of Ho3+is discussed in detail and further confirms through a comparative experiment.Our research gives an unusual perspective to tune the UC behavior of Er3+through co-doping Ho3+,which might be inspiring for achievement of single-band red UC emission.

Fast cooperative trajectory optimization and test verification for close-range satellite formation using Finite Fourier Series method

The process of formation reconfiguration for close-range satellite formation should take into account the risk of collisions between satellites.To this end,this paper presents a method to rapidly generate low-thrust collision-avoidance trajectories in the formation reconfiguration using Finite Fourier Series(FFS).The FFS method can rapidly generate the collision-avoidance threedimensional trajectory.The results obtained by the FFS method are used as an initial guess in the Gauss Pseudospectral Method(GPM)solver to verify the applicability of the results.Compared with the GPM method,the FFS method needs very little computing time to obtain the results with very little difference in performance index.To verify the effectiveness,the proposed method is tested and validated by a formation control testbed.Three satellite simulators in the testbed are used to simulate two-dimensional satellite formation reconfiguration.The simulation and experimental results show that the FFS method can rapidly generate trajectories and effectively reduce the risk of collision between satellites.This fast trajectory generation method has great significance for on-line,constantly satellite formation reconfiguration.

飞秒激光辐照诱导光致变色玻璃中的上转换发光可逆调控和3D光学信息存储

快速响应、高发光对比度、三维存储和信息无损读取是光致变色材料光存储应用的几个关键因素.具有多光子非线性吸收的飞秒激光直写技术以其加工速度快、加工精度高等独特优势,正成为玻璃三维空间微加工功能单元的有效工具.本工作研究了800 nm飞秒激光照射下稀土离子掺杂透明玻璃的光致变色性质,结果证实在800 nm飞秒激光辐照下玻璃展现了快速光致变色响应.在光致变色玻璃中实现了92%的上转换发光调控.光致变色玻璃可通过热刺激漂白回原色,在800 nm飞秒激光辐照和热处理交替刺激下,光致变色玻璃的透射率和上转换调控表现出良好的重现性.通过800 nm飞秒激光照射,可将数据信息写入透明玻璃内部,实现三维信息存储.结果表明,800 nm飞秒激光辐照诱导的光致变色玻璃是理想的光学数据存储介质.

Enhancement of solar-driven photocatalytic activity of oxygen vacancy-rich Bi/BiOBr/Sr_(2)LaF_(7)∶Yb^(3+),Er^(3+)composites through synergetic strategy of upconversion function and plasmonic effect

For better use of solar energy,the development of efficient broadband photocatalyst has attracted extraordinary attention.In this study,a ternary composite consisting of Sr_(2)LaF_(7)∶Yb^(3+),Er^(3+)upconversion(UC)nanocrystals and Bi nanoparticles loaded BiOBr nanosheets with oxygen vacancies(OVs,SLFBB)was designed and synthesized by multi-step solvent-thermal method.Mechanisms of in-situ formation of Bi nanoparticles and OVs in BiOBr/Sr_(2)LaF_(7)∶Yb^(3+),Er^(3+)composites(SFLB)are clarified.The Bi metal and OVs enhanced the light-harvesting capacity in the region of visible-near-infrared(Vis-NIR),and promoted the separation of electron-hole(e-/h+)pairs.Furthermore,the surface plasmon resonance(SPR)effect of Bi metal can improve the energy transfer from Sr_(2)LaF_(7)∶Yb^(3+),Er^(3+)to BiOBr via nonradiative energy transfer process,resulting in enhancing the light utilization from up-converting NIR into Vis light.Due to the synergistic effects of UC function,SPR and OVs,the SFLBB exhibited obviously enhanced photocatalytic ability for the degradation of BPA with a rate of 8.9×10^(-3) min^(-1),which is about 2.78 times higher than 3.2×10^(-3) min^(-1) of BiOBr(BOB)under UV-Vis-NIR light irradiation.This work provides a novel strategy for the project of high-efficiency Bismuth-based broadband photocatalysts,which is helpful to fur-ther understand the mechanism of enhanced photocatalysis by UC function and plasmonic effect.

Reply to Comment on"Reversible 3D optical data storage and information encryption in photomodulated transparent glass medium

Dear Editor,Tungsten-based photochromic materials are well known,suchastungsten-phosphateglasses,tungsten-telluriteglasses,andtungsten-borateglasses'.Photoluminescence glasses exhibit a wide range of application in the fields of display,lighting,laser and optical thermometry,et al.Combination of photochromic and luminescence can extend the application of luminescence materials2-7.Our focus is not on the development of new photochromic materials,but on the control of luminescence through photochromic reaction,especially achieved the real complex threedimensional patterns using laser directly writing technology in photo-modulated transparent glass.In our work2,the three-dimensional optical data storage and information encryption application of photochromic glass with luminescence was obtained.

Preparation and upconversion luminescence modification of YbPO4:Er3+inverse opal heterostructure

Photonic crystal heterostructures composed of YbPO4：Er^（3＋） inverse opal and polystyrene opal were prepared via a template-assisted process, which exhibited two photonic band gaps. The microstructure,phase and optical properties of photonic crystal heterostructures were investigated by x-ray diffraction,scanning electron microscopy, fluorescence spectroscopy, absorption spectroscopy, fluorescence lifetime,etc. The upconversion emission suppression caused by single photonic band gap from the following YbPO4：Er^（3＋） inverse opal or the upper opal was observed. The upconversion luminescence was strongly suppressed due to the two photonic band gap overlapping effect caused by the following YbPO4：Er^（3＋） inverse opal or the upper opal. The modified mechanisms of upconversion luminescence were discussed by the upconversion luminescence lifetime of YbPO4：Er^（3＋） photonic crystal heterostructures. The results demonstrated the modified upconversion luminescence is attributed to the photon trapping caused by Bragg reflection of photonic crystal heterostructures.

Color tunable and white light emitting via energy transfer in single-phase BiOCl:Er^(3+),Sm^(3+) phosphors for WLEDs

BiOCl crystal shows potential as efficient optical host due to its special layered structure. Here,the luminescence properties of the Er^3＋/Sm^3＋ co-doped BiOCl phosphors as single-phase phosphors were reported. Upon near ultraviolet excitation（NUV, 380 nm corresponding the ^4 I15/2→ ^4 G11/2 transition of Er^3＋ ions）, the phosphors exhibit the efficient characteristic emissions of Er^3＋ and Sm^3＋ ions simultaneously. The energy transfer（ET） from Er^3＋ to Sm^3＋ ions in the layered crystals has been validated by the variation of emission intensities and decay lifetimes respectively, which is ascribed to be a dipoledipole interaction. By virtue of the ET behavior and increasing Sm^3＋ ion concentration, the enhancing emission intensity of Sm^3＋ and the tunability of emission color from yellowish-green（0.318, 0.420） to white（0.343, 0.347） are realized. The results of our work indicate that the Er^3＋/Sm^3＋ co-doped BiOCI phosphor has a promising application serving as single component white emitting phosphors for NUV excited WLEDs.