Given the importance of alkenylsilanes in organosilicon chemistry and material science, direct transition-metal-catalyzed selective hydrosilylation of alkynes with hydrosilanes has emerged as apowerful platform for ac...Given the importance of alkenylsilanes in organosilicon chemistry and material science, direct transition-metal-catalyzed selective hydrosilylation of alkynes with hydrosilanes has emerged as apowerful platform for accessing such building blocks in a straightforwardand atom-economical fashion [1,2]. Among them,regio- and stereoselective hydrosilylations of terminal alkynesand symmetrical internal alkynes have been thoroughly studied,and a range of 3d transition-metal catalysts exhibited excellentb-(E), b-(Z), and a-selectivity in these transformations [3–9].Despite these major advances, crucial drawbacks exist in thecatalytic hydrosilylation between hydrosilanes and unsymmetricalinternal alkynes, particularly when done in a regiodivergent andstereocontrolled fashion. The representative examples are largelyrestricted to the use of electronically [10] or sterically [11] biasedalkynes (Fig. 1a).展开更多
基金supported by the National Natural Science Foundation of China(22322108)Natural Science Foundation of Jiangsu Province(BK20231521 and BK20221355)Jiangsu Specially Appointed Professors Plan(SR10900122),and start-up funds from Soochow University.
文摘Given the importance of alkenylsilanes in organosilicon chemistry and material science, direct transition-metal-catalyzed selective hydrosilylation of alkynes with hydrosilanes has emerged as apowerful platform for accessing such building blocks in a straightforwardand atom-economical fashion [1,2]. Among them,regio- and stereoselective hydrosilylations of terminal alkynesand symmetrical internal alkynes have been thoroughly studied,and a range of 3d transition-metal catalysts exhibited excellentb-(E), b-(Z), and a-selectivity in these transformations [3–9].Despite these major advances, crucial drawbacks exist in thecatalytic hydrosilylation between hydrosilanes and unsymmetricalinternal alkynes, particularly when done in a regiodivergent andstereocontrolled fashion. The representative examples are largelyrestricted to the use of electronically [10] or sterically [11] biasedalkynes (Fig. 1a).
