The fusion of digital technology and education has ushered in an era of intelligent educational environment.The course of Political Economy in colleges and universities not only imparts economic knowledge and cultivat...The fusion of digital technology and education has ushered in an era of intelligent educational environment.The course of Political Economy in colleges and universities not only imparts economic knowledge and cultivates financial quotient,but also bears the important task of improving students ideological and moral character.It is worth exploring how to effectively use digital technology to integrate ideological and political education into political economy more accurately.On the basis of building the ideological and political education system of political economy course,this paper explores the practical path of ideological and political education in the era of digital intelligence from three aspects:"before class","during class"and"after class".展开更多
Purpose:To explore the safety and clinical efficacy of transcatheter arterial chemoembolization(TACE)combined with simultaneous cone beam computed tomography(CBCT)-guided multipolar microwave ablation(MWA)in the treat...Purpose:To explore the safety and clinical efficacy of transcatheter arterial chemoembolization(TACE)combined with simultaneous cone beam computed tomography(CBCT)-guided multipolar microwave ablation(MWA)in the treatment of massive hepatocellular carcinoma(HCC).Materials and methods:Records of nine patients who underwent TACE combined with simultaneous CBCT-guided multipolar MWA for massive HCC,between January and June 2015,were retrospectively reviewed.Technical success rate,blood levels of liver function indicators,complications,and tumor response one month after treatmentwere investigated.Results:The technical success rate of TACE combined with simultaneous MWA was 100%.The mean procedure time was 195.0 min(range,125-350 min),the mean hospital stay after the treatment was 4.0±1.0 days(range,3-7 days),and no serious complications occurred.Minor complications were experienced by some patients but were relieved after conservative treatment.One month after treatment,enhanced CT revealed a complete response rate of 66.7%(6/9),a partial response rate of 22.2%(2/9),and a stable disease rate of 11.1%(1/9).Mild and reversible injury of liver function occurred in these patients.Conclusion:TACE combined with simultaneous CBCT-guided MWA for massive HCC was feasible and safe,and yielded a high response rate.展开更多
Objective:To assess the clinical efficacy and safety of transarterial embolization(TAE)in simultaneous combination with computed tomography(CT)-guided radiofrequency ablation(RFA)for recurrent or residual hepatocellul...Objective:To assess the clinical efficacy and safety of transarterial embolization(TAE)in simultaneous combination with computed tomography(CT)-guided radiofrequency ablation(RFA)for recurrent or residual hepatocellular carcinoma(HCC),and to determine the risk factors influencing local tumor progression following this procedure.Methods:One hundred eighteen patients with recurrent or residual HCC(tumor size,10–30 mm)underwent RFA.During the 19-month follow-up,59 patients received RFA only(RFA group),and the remaining 59 received RFA immediately after TAE(TAE+RFA group).All patients were followed up to observe the short-term therapeutic effects and complications.The cumulative local tumor progression rates in both groups were calculated using unpaired Student’s t tests and the Kaplan-Meier method.Results:The rate of major complications was 5.08%in the TAE+RFA group and 3.39%in the RFA group.The overall response rate was 96.61%in the TAE+RFA group and 79.66%in the RFA group(P=0.008).The disease control rate was significantly higher in the TAE+RFA group than in the RFA group(94.92%vs.79.66%,P=0.024).The median time to local tumor progression was 4.8 months in the RFA group and 9.6 months in the TAE+RFA group.The cumulative local tumor progression rate at 1 year was 10.60%in the RFA group and 23.60%in the TAE+RFA group(P=0.016).Conclusion:TAE in simultaneous combination with CT-guided RFA was effective and safe against recurrent or residual HCC.Local tumor progression can be minimized by the complete ablation of targeted iodized oil deposits after simultaneous TAE.展开更多
Electrolytes are widely considered as a key component in Li–O;batteries (LOBs) because they greatly affect the discharge-charge reaction kinetics and reversibility.Herein,we report that 1,3-dimethyl-2-imidazolidinone...Electrolytes are widely considered as a key component in Li–O;batteries (LOBs) because they greatly affect the discharge-charge reaction kinetics and reversibility.Herein,we report that 1,3-dimethyl-2-imidazolidinone (DMI) is an excellent electrolyte solvent for LOBs.Comparing with conventional ether and sulfone based electrolytes,it has higher Li_(2)O_(2)and Li_(2)CO_(3)solubility,which on the one hand depresses cathode passivation during discharge,and on the other hand promotes the liquid-phase redox shuttling during charge,and consequently lowers the overpotential and improves the cyclability of the battery.However,despite the many advantages at the cathode side,DMI is not stable with bare Li anode.Thus,we have developed a pretreatment method to grow a protective artificial solid-state electrolyte interface(SEI) to prevent the unfavorable side-reactions on Li.The SEI film was formed via the reaction between fluorine-rich organic reagents and Li metal.It is composed of highly Li^(+)-conducting Li_(x)BO_(y),LiF,Li_(x)NO_(y),Li_(3)N particles and some organic compounds,in which Li_(x)BO_(y)serves as a binder to enhance its mechanical strength.With the protective SEI,the coulombic efficiency of Li plating/stripping in DMI electrolyte increased from 20%to 98.5%and the fixed capacity cycle life of the assembled LOB was elongated to205 rounds,which was almost fivefold of the cycle life in dimethyl sulfoxide (DMSO) or tetraglyme(TEGDME) based electrolytes.Our work demonstrates that molecular polarity and ionic solvation structure are the primary issues to be considered when designing high performance Li–O;battery electrolytes,and cross-linked artificial SEI is effective in improving the anodic stability.展开更多
基金Quality Engineering and Teaching Reform Project of Zhaoqing University in 2022(zlgc202209)Education Research Project of Zhaoqing Education Development Research Institute in 2023(ZQJYY2023025).
文摘The fusion of digital technology and education has ushered in an era of intelligent educational environment.The course of Political Economy in colleges and universities not only imparts economic knowledge and cultivates financial quotient,but also bears the important task of improving students ideological and moral character.It is worth exploring how to effectively use digital technology to integrate ideological and political education into political economy more accurately.On the basis of building the ideological and political education system of political economy course,this paper explores the practical path of ideological and political education in the era of digital intelligence from three aspects:"before class","during class"and"after class".
基金supported by the National Natural Science Foundation of China(No.81771955)Guangzhou Science and Technology Program,key projects of collaborative innovation of health medicine(No201704020228)+1 种基金Guangzhou Science and Technology Program,key projects of collaborative innovation of production,learning and research(No.201704020134)Sun Yat-sen University Clinical Trial 5010Project(No.2016002).
文摘Purpose:To explore the safety and clinical efficacy of transcatheter arterial chemoembolization(TACE)combined with simultaneous cone beam computed tomography(CBCT)-guided multipolar microwave ablation(MWA)in the treatment of massive hepatocellular carcinoma(HCC).Materials and methods:Records of nine patients who underwent TACE combined with simultaneous CBCT-guided multipolar MWA for massive HCC,between January and June 2015,were retrospectively reviewed.Technical success rate,blood levels of liver function indicators,complications,and tumor response one month after treatmentwere investigated.Results:The technical success rate of TACE combined with simultaneous MWA was 100%.The mean procedure time was 195.0 min(range,125-350 min),the mean hospital stay after the treatment was 4.0±1.0 days(range,3-7 days),and no serious complications occurred.Minor complications were experienced by some patients but were relieved after conservative treatment.One month after treatment,enhanced CT revealed a complete response rate of 66.7%(6/9),a partial response rate of 22.2%(2/9),and a stable disease rate of 11.1%(1/9).Mild and reversible injury of liver function occurred in these patients.Conclusion:TACE combined with simultaneous CBCT-guided MWA for massive HCC was feasible and safe,and yielded a high response rate.
基金supported by the National Natural Science Foundation of China(No.81771955)Sun Yat-sen University Clinical Trial 5010Project(No.2016002)Guangzhou Science and Technology Program of China(No.201704020134)
文摘Objective:To assess the clinical efficacy and safety of transarterial embolization(TAE)in simultaneous combination with computed tomography(CT)-guided radiofrequency ablation(RFA)for recurrent or residual hepatocellular carcinoma(HCC),and to determine the risk factors influencing local tumor progression following this procedure.Methods:One hundred eighteen patients with recurrent or residual HCC(tumor size,10–30 mm)underwent RFA.During the 19-month follow-up,59 patients received RFA only(RFA group),and the remaining 59 received RFA immediately after TAE(TAE+RFA group).All patients were followed up to observe the short-term therapeutic effects and complications.The cumulative local tumor progression rates in both groups were calculated using unpaired Student’s t tests and the Kaplan-Meier method.Results:The rate of major complications was 5.08%in the TAE+RFA group and 3.39%in the RFA group.The overall response rate was 96.61%in the TAE+RFA group and 79.66%in the RFA group(P=0.008).The disease control rate was significantly higher in the TAE+RFA group than in the RFA group(94.92%vs.79.66%,P=0.024).The median time to local tumor progression was 4.8 months in the RFA group and 9.6 months in the TAE+RFA group.The cumulative local tumor progression rate at 1 year was 10.60%in the RFA group and 23.60%in the TAE+RFA group(P=0.016).Conclusion:TAE in simultaneous combination with CT-guided RFA was effective and safe against recurrent or residual HCC.Local tumor progression can be minimized by the complete ablation of targeted iodized oil deposits after simultaneous TAE.
文摘Electrolytes are widely considered as a key component in Li–O;batteries (LOBs) because they greatly affect the discharge-charge reaction kinetics and reversibility.Herein,we report that 1,3-dimethyl-2-imidazolidinone (DMI) is an excellent electrolyte solvent for LOBs.Comparing with conventional ether and sulfone based electrolytes,it has higher Li_(2)O_(2)and Li_(2)CO_(3)solubility,which on the one hand depresses cathode passivation during discharge,and on the other hand promotes the liquid-phase redox shuttling during charge,and consequently lowers the overpotential and improves the cyclability of the battery.However,despite the many advantages at the cathode side,DMI is not stable with bare Li anode.Thus,we have developed a pretreatment method to grow a protective artificial solid-state electrolyte interface(SEI) to prevent the unfavorable side-reactions on Li.The SEI film was formed via the reaction between fluorine-rich organic reagents and Li metal.It is composed of highly Li^(+)-conducting Li_(x)BO_(y),LiF,Li_(x)NO_(y),Li_(3)N particles and some organic compounds,in which Li_(x)BO_(y)serves as a binder to enhance its mechanical strength.With the protective SEI,the coulombic efficiency of Li plating/stripping in DMI electrolyte increased from 20%to 98.5%and the fixed capacity cycle life of the assembled LOB was elongated to205 rounds,which was almost fivefold of the cycle life in dimethyl sulfoxide (DMSO) or tetraglyme(TEGDME) based electrolytes.Our work demonstrates that molecular polarity and ionic solvation structure are the primary issues to be considered when designing high performance Li–O;battery electrolytes,and cross-linked artificial SEI is effective in improving the anodic stability.